2026
conference-paper
OpenAlex
Aidan Crozier, Celia Gagnon, Elizabeth M. Malick, Alexis Schulz et autres
We report on an exploratory assessment of cerebral hemodynamics and autoregulatory impairment using non-invasive diffuse optical monitoring during extracorporeal membrane oxygenation and transition to the Berlin Heart EXCOR ventricular assist device in 3 pediatric patients.
us
(code pays fourni par la source)
2026
conference-paper
OpenAlex
Nicolina R. Ranieri, Rodrigo Forti, Tiffany S. Ko, Alyssa Seeney et autres
Diffuse correlation spectroscopy can quantify cerebral blood flow and assess autoregulation during neonatal cardiac surgery. After cardiopulmonary bypass, impaired autoregulation was more likely among neonates who underwent deep hypothermic circulatory arrest instead of selective cerebral perfusion.
us
(code pays fourni par la source)
2025
conference-abstract
OpenAlex
Darci E. Anderson, Jeremy L. Herrmann, Kumaran Senthil, Aidan Crozier et autres
Introduction: Hemodynamic-directed cardiopulmonary resuscitation (HD-CPR) targets blood pressure (BP) goals during resuscitation and has shown improved outcomes compared to conventional algorithmic CPR. However, the relationship between specific BP targets and cerebral health remains poorly understood. Objective: Evaluate the association of intra- and …
us
(code pays fourni par la source)
2025
conference-abstract
OpenAlex
Darci E. Anderson, Jeremy L. Herrmann, Kumaran Senthil, Aidan Crozier et autres
Introduction: Hemodynamic-directed cardiopulmonary resuscitation (HD-CPR) targets blood pressure (BP) goals during resuscitation and has shown improved outcomes compared to conventional algorithmic CPR. However, the relationship between specific BP targets and cerebral health remains poorly understood. Objective: Evaluate the association of intra- and …
us
(code pays fourni par la source)
2025
conference-abstract
OpenAlex
Tiffany S. Ko, Darci E. Anderson, Kumaran Senthil, Jeremy L. Herrmann et autres
Introduction: We have developed non-invasive optical devices for concurrent monitoring of cerebral and somatic hemodynamics using frequency-domain diffuse optical spectroscopy (FD-DOS) and diffuse correlation spectroscopy (DCS). Objectives: In a pediatric swine model of asphyxia-associated cardiac arrest, compare cerebral and somatic hemodynamics during …
us
(code pays fourni par la source)
2025
conference-abstract
OpenAlex
Elizabeth M. Malick, Aidan Crozier, Alyssa Seeney, Darci E. Anderson et autres
Background: Children requiring ECMO support after Fontan completion represent a high-risk population with previous ELSO data (1987-2009) demonstrating low survival rates of 35%. Methods and Objectives: Retrospective analysis of children undergoing their first ECMO run after Fontan completion between 2010 and 2023. …
us
(code pays fourni par la source)
2025
conference-abstract
OpenAlex
Aidan Crozier, Elizabeth M. Malick, Alyssa Seeney, Darci E. Anderson et autres
Background: In 2010, a system to rapidly deploy the (Extracorporeal Membrane Oxygenation) ECMO team was implemented utilizing an in-house emergency response platform (VECOM). In 2020, our institution launched a quality improvement (QI) initiative to standardize nomenclature and refine workflows resulting in enhanced …
us
(code pays fourni par la source)
2025
conference-paper
OpenAlex
Darci E. Anderson, Aidan Crozier, Kumaran Senthil, Jeremy L. Herrmann et autres
We utilize non-invasive diffuse optical neuromonitoring to quantify cerebral hemodynamics during hemodynamic-directed cardiopulmonary resuscitation (HD-CPR) strategies that maintained either higher or lower arterial blood pressure targets in a pediatric swine model of asphyxia-associated cardiac arrest.
us
(code pays fourni par la source)
2024
conference-abstract
OpenAlex
April M. Hurlock, Alyssa Seeney, Nicolina R. Ranieri, Ryan Burnett et autres
Introduction: Cerebral autoregulation (CAR) mechanisms, which maintain cerebral blood flow (CBF) over a range of mean arterial pressures (MAP), are impaired after cardiac arrest. Metrics of CAR impairment can be calculated from MAP and a CBF surrogate. Brain tissue oxygenation (StO 2 …
us
(code pays fourni par la source)
2024
conference-abstract
OpenAlex
Tiffany S. Ko, Katsunari Terakawa, Benjamin F. Smood, Julia Slovis et autres
Introduction: We present a novel demonstration of brain-directed management of venoarterial extracorporeal membrane oxygenation (ECMO) using real-time feedback from non-invasive neurometabolic optical monitoring (NOM) of the cerebral oxygen extraction fraction (OEF) in pediatric swine. In our prior work, OEF>0.82 was associated with …
us
(code pays fourni par la source)
2024
conference-paper
OpenAlex
Nicolina R. Ranieri, Rodrigo M. Menezes Forti, Tiffany S. Ko, Alyssa Seeney et autres
We demonstrate the feasibility of novel diffuse optical neuromonitoring to continuously quantify cerebral blood flow and oxygenation during antegrade cerebral perfusion in neonates with hypoplastic left heart syndrome during the Norwood procedure.
us
(code pays fourni par la source)