Wendy Espinoza Camejo

Abstract Tu0014: Single cell RNA sequencing reveals adaptive and maladaptive transcriptional signature across aortic cell types in a mouse model of Autosomal Recessive Cutis Laxa type 1B

Wendy Espinoza Camejo, Emily E. Bramel, Leda Restrepo, Elena Gallo MacFarlane

Thoracic aorta aneurysms (TTA) are localized dilations that predispose the aorta to dissection or rupture. Autosomal Recessive Cutis Laxa type 1B (ARCL1B) is a connective tissue disorder caused by homozygous loss of function mutations in the EFEMP2/FBLN4 gene. This disorder is associated …

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Abstract Tu0014: Single cell RNA sequencing reveals adaptive and maladaptive transcriptional signature across aortic cell types in a mouse model of Autosomal Recessive Cutis Laxa type 1B

Wendy Espinoza Camejo, Emily E. Bramel, Leda Restrepo, Elena Gallo MacFarlane

Thoracic aorta aneurysms (TTA) are localized dilations that predispose the aorta to dissection or rupture. Autosomal Recessive Cutis Laxa type 1B (ARCL1B) is a connective tissue disorder caused by homozygous loss of function mutations in the EFEMP2/FBLN4 gene. This disorder is associated …

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Intrinsic Gata4 expression sensitizes the aortic root to dilation in a Loeys-Dietz syndrome mouse model

Emily E. Bramel, Wendy Espinoza Camejo, Tyler J. Creamer, Leda Restrepo et autres

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