Relaxed constraint and thermal desensitization of the cold-sensing ion channel TRPM8 in mammoths
Sravanthi Chigurapati, Mike Sulak, Webb Miller, Vincent J. Lynch
Abstract Unlike the living elephants, which live in warm tropical and subtropical habitats, mammoths lived in extreme cold environments where average winter temperatures ranged from −30° to −50°C. Like other cold adapted and artic species, mammoths evolved of suite of morphological and …
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4 citations
bioRxiv (Cold Spring Harbor Laboratory)