Accès ouvert
2026
supplementary-materials
OpenAlex
figshare admin karger, Keisuke Kanetaka, Kei Koyama, Tomonori Tsuruhashi et autres
Introduction: Mature and immature teratomas contain diverse histological components; however, their tissue-level spatial organization remains poorly understood. This proof-of-concept study aimed to develop a reproducible digital pathology workflow for quantifying the spatial distances among histological components of ovarian teratomas.Methods: Four representative mature …
ch
(code pays fourni par la source)
Accès ouvert
2026
supplementary-materials
OpenAlex
figshare admin karger, Keisuke Kanetaka, Kei Koyama, Tomonori Tsuruhashi et autres
Introduction: Mature and immature teratomas contain diverse histological components; however, their tissue-level spatial organization remains poorly understood. This proof-of-concept study aimed to develop a reproducible digital pathology workflow for quantifying the spatial distances among histological components of ovarian teratomas.Methods: Four representative mature …
ch
(code pays fourni par la source)
2026
article
OpenAlex
Keisuke Kanetaka, Kei Koyama, Tomonori Tsuruhashi, Hikaru Tsukita et autres
INTRODUCTION: Mature (MT) and immature teratomas (ITs) contain diverse histological components; however, their tissue-level spatial organization remains poorly understood. This proof-of-concept study aimed to develop a reproducible digital pathology workflow for quantifying the spatial distances among histological components of ovarian teratomas. METHODS: …
jp
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Kei Koyama, Hikaru Tsukita, Takahiro Ishinari, Ayana Takahashi et autres
Clusters of epithelial cells of the fallopian tube exhibiting aberrant p53 expression, termed "p53 signatures," are detected at a relatively high frequency and have been regarded as putative precursors of high-grade serous carcinoma (HGSC). In contrast, the recently proposed "β-catenin signature" represents …
jp
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Ken Miyabe, Michinobu Umakoshi, Yukitsugu Kudo‐Asabe, Kei Koyama et autres
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are clinically heterogeneous, making prediction of metastatic behavior challenging. This study examined Cell Adhesion Molecule 1 (CADM1) and the differentially expressed in adenocarcinoma of the lung-1 expression in 75 resected GEP-NETs and evaluated their associations with clinicopathological features, …
jp
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Ken Miyabe, Hikaru Tsukita, Makoto Yoshida, Yukitsugu Kudo-Asabe et autres
Background: The involvement of human papillomavirus（HPV）in bladder cancer remains unclear. This study aimed to investigate the relationship between HPV infection and the expression of p16, a surrogate marker of HPV infection, in bladder cancer tissues. Methods: We retrospectively analyzed 132 surgically treated …
jp
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Hikaru Tsukita, Kei Koyama, Takahiro Ishinari, Ayana Takahashi et autres
BACKGROUND: PEComa is a mesenchymal tumor that can occur in various organs including the uterus and soft tissues. PEComas are composed of perivascular epithelioid cells, and angiomyolipoma (AML), clear cell sugar tumor (CCST), and lymphangiomyomatosis (LAM) are considered lesions of the same …
jp
(code pays fourni par la source)