Accès ouvert
2026
article
OpenAlex
Farhad Dehkhoda, Jingjing Xing, Desye Misganaw, Keith Mutunduwe et autres
G protein-coupled receptors (GPCRs) classically signal through cognate heterotrimeric G proteins to regulate second messengers such as cyclic adenosine monophosphate (cAMP) and intracellular Ca 2+ . Yet when two GPCRs are co-expressed, their combined activation can generate emergent outputs, including atypical Ca …
au
(code pays fourni par la source)
2025
article
OpenAlex
Farhad Dehkhoda, Mitchell Ringuet, Emily A. Whitfield, Keith Mutunduwe et autres
au
(code pays fourni par la source)
Accès ouvert
2025
dataset
OpenAlex
Luke Sorensen, Ayame Saito, Sabrina Poon, Myat Noe Han et autres
This upload is associated with the software, Gut Analysis Toolbox (GAT). If you use it please cite: Sorensen et al. Gut Analysis Toolbox: Automating quantitative analysis of enteric neurons. J Cell Sci 2024; jcs.261950. doi: https://doi.org/10.1242/jcs.261950 The upload contains StarDist models for …
au, pt, es, de
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Luke Sorensen, Adam Humenick, Sabrina Poon, Myat Noe Han et autres
The enteric nervous system (ENS) consists of an extensive network of neurons and glial cells embedded within the wall of the gastrointestinal (GI) tract. Alterations in neuronal distribution and function are strongly associated with GI dysfunction. Current methods for assessing neuronal distribution …
us, au, pt, de, es
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Luke Sorensen, Adam Humenick, Sabrina Poon, Myat Noe Han et autres
Abstract The enteric nervous system (ENS) plays an important role in coordinating gut function. The ENS consists of an extensive network of neurons and glial cells within the wall of the gastrointestinal tract. Alterations in neuronal distribution, function, and type are strongly …
au, us, pt, de, es
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Farhad Dehkhoda, Mitchell Ringuet, Emily A. Whitfield, Keith Mutunduwe et autres
au, de, us
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Farhad Dehkhoda, Mitchell Ringuet, Emily A. Whitfield, Keith Mutunduwe et autres
Summary All cells face the challenge of integrating multiple extracellular signals to produce relevant physiological responses. Different combinations of G protein-coupled receptors, when co-expressed, can lead to distinct cellular outputs, yet the molecular basis for this co-operativity is controversial. One such interaction …
au
(code pays fourni par la source)
2023
conference-abstract
OpenAlex
Pradeep Rajasekhar, Luke Sorensen, Keith Mutunduwe, Yinghan She et autres
Accès ouvert
2022
dataset
OpenAlex
Luke Sorensen, Ayame Saito, Sabrina Poon, Myat Noe Han et autres
This upload is associated with the software, Gut Analysis Toolbox (GAT). If you use it please cite: Sorensen et al. Gut Analysis Toolbox: Automating quantitative analysis of enteric neurons. J Cell Sci 2024; jcs.261950. doi: https://doi.org/10.1242/jcs.261950 The upload contains StarDist models for …
au, pt, es, de
(code pays fourni par la source)
Accès ouvert
2022
dataset
OpenAlex
Luke Sorensen, Ayame Saito, Sabrina Poon, Myat Noe Han et autres
This upload is associated with the software, Gut Analysis Toolbox (GAT). It contains StarDist models for segmenting enteric neurons in 2D, enteric neuronal subtypes in 2D and UNet model for enteric ganglia in 2D in gut wholemount tissue. GAT is implemented in …
au, pt, es, de
(code pays fourni par la source)