Darin Poei

Validation of prognostic scores in Hispanic patients with advanced solid tumors enrolled in a single-center phase I clinical trial program.

Darin Poei, Zehui He, Ming Li, Hadi Erfani et autres

1541 Background: Prognostic scores are commonly used to guide enrollment in early-phase oncology trials. Despite their widespread use, these models have not been specifically evaluated in Hispanic patients, to the best of our knowledge — a population historically underrepresented in clinical trials. …

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ABCL-1228: CNS Prophylaxis in DLBCL and HGBCL: Comparing Intrathecal, High-Dose Methotrexate, and Combination Strategies

Graham C. Parker, Lawrence D. Kaplan, Julian Hardy McLain, Han W. Tun et autres

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POSTER: ABCL-1228 CNS Prophylaxis in DLBCL and HGBCL: Comparing Intrathecal, High-Dose Methotrexate, and Combination Strategies

Graham C. Parker, L Kaplan, Julian Hardy McLain, Han W. Tun et autres

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696 | OUTCOME DISPARITIES IN PRIMARY CNS LYMPHOMA: A RETROSPECTIVE ANALYSIS AT AN ACADEMIC CENTER WITH A PREDOMINANTLY HISPANIC PATIENT POPULATION

Yeshanew Teklie, Han Tun, Darin Poei, Gordon Parker et autres

mutation testing was performed in 8 pts, and revealed 7 cases of MCD type and 1 case of A53 type (LymphGen algorithm).Among those subtypes, the ORR and CRR of 7 pts with MCD type were both 85.7%.The high-frequency mutated genes in these …

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Impact of Modern Systemic Therapies on Survival in Patients with Anaplastic Thyroid Cancer: A Single-Center Retrospective Cohort Review

Austin Luong, Darin Poei, Lydia D. Chow, Ming Li et autres

BACKGROUND: Anaplastic thyroid carcinoma (ATC) is a highly aggressive cancer historically associated with a median survival of about 5 months. Recent advances in tumor genomic testing have identified targetable BRAF mutations in about 35-40% of ATC cases and have shown high levels …

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Advances in adoptive cell therapies in small cell lung cancer

Eljie Isaak Bragasin, Justin Cheng, Lauren Ford, Darin Poei et autres

Small cell lung cancer (SCLC) is an aggressive tumor characterized by early metastasis and resistance to treatment, making it a prime target for therapeutic investigation. The current standard of care for frontline treatment involves a combination of chemotherapeutic agents and immune checkpoint …

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Table 5 from Real-World Incidence of Anaplastic Lymphoma Kinase Alterations in Hispanics with Non–Small Cell Lung Cancer at a Large Academic Institution in Los Angeles

Darin Poei, Sana Ali, Jacob Thomas, Jorgé Nieva et autres

Logistic regression for ALK alterations evaluating Hispanic ethnicity and controlling for site of treatment, age at initial diagnosis, gender, and smoking

Table 2 from Real-World Incidence of Anaplastic Lymphoma Kinase Alterations in Hispanics with Non–Small Cell Lung Cancer at a Large Academic Institution in Los Angeles

Darin Poei, Sana Ali, Jacob Thomas, Jorgé Nieva et autres

Prevalence of adenocarcinoma histology, stage at diagnosis, and metastasis to brain by race/ethnicity

Table 4 from Real-World Incidence of Anaplastic Lymphoma Kinase Alterations in Hispanics with Non–Small Cell Lung Cancer at a Large Academic Institution in Los Angeles

Darin Poei, Sana Ali, Jacob Thomas, Jorgé Nieva et autres

Initial ALK alteration identification by molecular testing

Table 6 from Real-World Incidence of Anaplastic Lymphoma Kinase Alterations in Hispanics with Non–Small Cell Lung Cancer at a Large Academic Institution in Los Angeles

Darin Poei, Sana Ali, Jacob Thomas, Jorgé Nieva et autres

Reported ALK prevalence across the Hispanic populations in Latin America and Florida/Puerto Rico from literature search

Table 3 from Real-World Incidence of Anaplastic Lymphoma Kinase Alterations in Hispanics with Non–Small Cell Lung Cancer at a Large Academic Institution in Los Angeles

Darin Poei, Sana Ali, Jacob Thomas, Jorgé Nieva et autres

Prevalence of ALK alterations, median age at diagnosis, prevalence of males and females, never smokers, stage IV at diagnosis, and brain metastasis in the ALK population by race/ethnicity

Table 1 from Real-World Incidence of Anaplastic Lymphoma Kinase Alterations in Hispanics with Non–Small Cell Lung Cancer at a Large Academic Institution in Los Angeles

Darin Poei, Sana Ali, Jacob Thomas, Jorgé Nieva et autres

Summary of demographic features of patients with NSCLC treated at the LAG and Norris