Shruthi Vasanthaiah

Nanopore sequencing panel for saliva-based host pharmacogenomic screening in anti-tubercular therapy

Priyanka Yadav, Swarup A.V. Shah, Aishwarya S. Babu, Minal Paradkar et autres

Abstract Rationale Host genotypes can predict subtherapeutic anti-tubercular drug exposures and treatment-associated toxicities. Screening for these variants could enable personalized dosing, but scalable assays for second-line drugs are lacking. Objectives We developed a nanopore sequencing panel to detect host variants affecting anti-tuberculosis …

in, Afrique du Sud, us (code pays fourni par la source)

Genomic perspectives on NDM Salmonella Typhi, and a case report from India

Shruthi Vasanthaiah, Pritibala Takey, Prasanna Kumar Selvam, Supraja Mohan et autres

in (code pays fourni par la source)

Breast cancer genomic analyses reveal genes, mutations, and signaling networks

Gowrang Kasaba Manjunath, Srihari Sharma, Disha Nashier, Shruthi Vasanthaiah et autres

in (code pays fourni par la source)

Culture-Free Whole Genome Sequencing of Mycobacterium tuberculosis Using Ligand-Mediated Bead Enrichment Method

Shruthi Vasanthaiah, Renu Verma, Ajay Kumar, Aravind K. Bandari et autres

Abstract Background Direct whole genome sequencing (WGS) of Mycobacterium tuberculosis (Mtb) can be used as a tool to study drug resistance, mixed infections, and within-host diversity. However, WGS is challenging to obtain from clinical samples due to low number of bacilli against …

in, us (code pays fourni par la source)

Culture-free whole genome sequencing of Mycobacterium tuberculosis using ligand-mediated bead enrichment method

Shruthi Vasanthaiah, Renu Verma, Ajay Kumar, Aravind K. Bandari et autres

ABSTRACT Background Direct whole genome sequencing (WGS) of Mycobacterium tuberculosis ( Mtb ) can be used as a tool to study drug resistance, mixed infections, and within host diversity. However, WGS is challenging from clinical samples due to low number of bacilli …

in, us (code pays fourni par la source)

The trends of isolation and antimicrobial susceptibility of group B Streptococcus in urine culture: a 7-years cross sectional study

Rachana Kannambath, Shruthi Vasanthaiah, Imola Jamir, Haritha Sagili et autres

Background: Group B Streptococcus (GBS)/Streptococcus agalactiae (S. agalactiae) is a common rectovaginal colonizer, thereby a potential agent of neonatal and maternal infection. This study estimates the trends of isolation of GBS, its antimicrobial profile in urine culture and the demographic characteristics of …

in (code pays fourni par la source)