Francesco Galletti

Twelve-Month Effectiveness of Dupilumab on Eosinophilic Otitis Media in Patients with Severe Chronic Rhinosinusitis with Nasal Polyps: A Multicenter Observational Study

Cosimo Galletti, Giovanna Stilo, Federico Sireci, Federica Giammona Indaco et autres

Background Eosinophilic otitis media (EOM) is a refractory type 2 inflammatory disease of the middle ear, frequently associated with asthma and chronic rhinosinusitis with nasal polyps (CRSwNP). Conventional otologic treatments often provide incomplete or transient benefit. Because EOM and CRSwNP may share …

it (code pays fourni par la source)

Genomic and Epigenomic Advances in Hearing Loss: Molecular Mechanisms, Diagnostics, and Emerging Therapies

Giuseppe Alberti, Francesco Galletti, Daniele Portelli, Cosimo Galletti et autres

Background: Hearing loss is a widespread sensory disorder affecting over 1.5 billion people worldwide, with the number projected to exceed 700 million by 2050. It imposes social and economic burdens across all ages and regions. Approximately half of adult cases are preventable, …

it, be (code pays fourni par la source)

Mood and Cognitive Disorders Following Hearing Loss: Impact of Hearing Aid Timing

Giuseppe Alberti, Sabrina Loteta, Daniele Portelli, Cosimo Galletti et autres

Background: Hearing loss is one of the most common yet often overlooked sensory deficits worldwide, with consequences extending well beyond auditory function. Mounting evidence highlights the complex interrelationships among hearing loss, cognitive decline, and psychosocial well-being. Neural mechanisms underlying this association include …

it, be, fr (code pays fourni par la source)

A RARE CASE OF A HUGE PLEOMORPHIC ADENOMA OF MINOR SALIVARY GLANDS IN THE PARAPHARYNGEAL SPACE

Bruno Galletti, Francesco Freni, Francesco Grazia, Viviana Nicastro et autres

Parapharyngeal space lesions account for only 0.5% of head and neck tumours. A 63-year-old male presented primary pleomorphic adenomas arising de novo from minor salivary glands in the parapharyngeal space. We describe the clinical features, pathology, radiological findings and treatment of this …

it (code pays fourni par la source)

Endoscopic Endonasal Repair of Bilateral Choanal Atresia in a Neonate with Placement of a Steroid-Eluting Bioabsorbable Nasal Stent (PROPEL) Using a Customised Alternative Insertion Technique: A Case Report and Literature Review

Cosimo Galletti, Daniele Portelli, Maria Grazia Ferrisi, Fabiana Gambino et autres

INTRODUCTION: Bilateral congenital choanal atresia (CCA) is a rare, life-threatening condition in neonates. This is the first reported case of PROPEL steroid-eluting stent use in a seven-day-old bilateral CCA neonate, with a customised technique developed to overcome limitations of the standard applicator. …

it (code pays fourni par la source)

ChatGPT in the Management of Chronic Rhinosinusitis with Nasal Polyps: Promising Support or Digital Illusion? Insights from a Multicenter Observational Study

Riccardo Manzella, Angelo Immordino, Cosimo Galletti, Federica Giammona Indaco et autres

Background/Objective: Chronic rhinosinusitis with nasal polyps is a chronic inflammatory disease with a significant impact on quality of life and is frequently associated, from a pathogenetic perspective, with type 2 inflammation. The introduction of biologic therapies has marked a turning point in …

it (code pays fourni par la source)

Mepolizumab in chronic rhinosinusitis with nasal polyps: Real life data in a multicentric Sicilian experience

Cosimo Galletti, Federico Sireci, Giovanna Stilo, María Antonietta Barbieri et autres

BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by a type 2 pattern of inflammation. Mepolizumab was approved for the treatment of CRSwNP in 2021. However, there is a lack of real-life studies. AIM: This work aimed to evaluate the effectiveness …

it (code pays fourni par la source)

Investigation of Deficits in Auditory Emotional Content Recognition by Adult Cochlear Implant Users through the Study of Electroencephalographic Gamma and Alpha Asymmetry and Alexithymia Assessment

Giulia Cartocci, Bianca Maria Serena Inguscio, Andrea Giorgi, Dario Rossi et autres

BACKGROUND/OBJECTIVES: Given the importance of emotion recognition for communication purposes, and the impairment for such skill in CI users despite impressive language performances, the aim of the present study was to investigate the neural correlates of emotion recognition skills, apart from language, …

it, cn (code pays fourni par la source)

Characterization of Cochlear Implant Artifact and Removal Based on Multi-Channel Wiener Filter in Unilateral Child Patients

Dario Rossi, Giulia Cartocci, Bianca Maria Serena Inguscio, Giulia Capitolino et autres

Cochlear implants (CI) allow deaf patients to improve language perception and improving their emotional valence assessment. Electroencephalographic (EEG) measures were employed so far to improve CI programming reliability and to evaluate listening effort in auditory tasks, which are particularly useful in conditions …

it, cn (code pays fourni par la source)

Impact of the Sars-COVID-19 Pandemic on the “Early Diagnosis” of Laryngeal Tumors: Data From Monocentric Tertiary Care Hospital of South Italy

Cosimo Galletti, Laura De Marco, Francesco Ciodaro, Francesco Freni et autres

it (code pays fourni par la source)

Dupilumab in chronic rhinosinusitis with nasal polyps: Real life data in a multicentric Sicilian experience

Cosimo Galletti, Martina Ragusa, Federico Sireci, Francesco Ciodaro et autres

OBJECTIVE: This study aimed to evaluate the effectiveness and safety of dupilumab during the first year of treatment in a real-life setting, focusing on improvement in nasal polyp score (NPS) as well as specific symptoms, quality of life and olfactory function. METHODOLOGY/PRINCIPAL: …

it (code pays fourni par la source)

Music in noise recognition: An EEG study of listening effort in cochlear implant users and normal hearing controls

Giulia Cartocci, Bianca Maria Serena Inguscio, Andrea Giorgi, Alessia Vozzi et autres

Despite the plethora of studies investigating listening effort and the amount of research concerning music perception by cochlear implant (CI) users, the investigation of the influence of background noise on music processing has never been performed. Given the typical speech in noise …

it, jp (code pays fourni par la source)