Anna Horňáková

Carobs’ impact on human health: a narrative review

Daniela Bonofilgio, Ioanna Tsiligianni, Antonios Koutelidakis, Maria Hassapidou et autres

). The aim of this narrative review was to summarise the current scientific knowledge on carobs, regarding their impact on human health and possible associated benefits. A comprehensive literature search was conducted in the electronic database of Medline/PubMed to identify original studies …

it, gr, fr, be, us, vn, de, ae, cy (code pays fourni par la source)

From GDPR compliance to cyber resilience: Systemic vulnerabilities in Czech healthcare technology

Anna Horňáková, David Jirsa, Martin Staněk, Petr Šmíd

cz (code pays fourni par la source)

Systemic mutagen exposures reported by normal kidney cell genomes

Yichen Wang, W. Knight, Aida Ferreiro-Iglesias, Behnoush Abedi-Ardekani et autres

Abstract Lifestyle, environmental and other exposures to exogenous mutagens generate somatic mutations in normal human cells in vivo and increase cancer risk. However, the global repertoire of exogenous mutagen exposures is uncertain. The mutational signatures of mutagens in normal tissues offer opportunities …

gb, fr, jp, ro, ru, cz, ch, rs, br, pt, lt, ca, th, us (code pays fourni par la source)

Using Mendelian randomization to investigate etiologic heterogeneity across renal cell carcinoma subtypes

Timothy Winter, Om Jahagirdar, Mark P. Purdue, Diptavo Dutta et autres

BACKGROUND: Renal cell carcinoma (RCC) histological subtypes clear cell RCC (ccRCC; >75% of cases) and papillary RCC (papRCC; ∼15%) exhibit distinct molecular and genetic profiles, patient demographics, and prognoses. Previous epidemiologic studies have identified several risk factors for overall RCC, although few …

us, fr (code pays fourni par la source)

Performance of 8 Smoking Metrics for Modeling Survival in Head and Neck Squamous Cell Carcinoma

Gary J. Macfarlane, Paul Brennan, Mari Nygård, Wei Xu et autres

Importance: Cigarette smoking is a strong risk factor for mortality in patients diagnosed with head and neck squamous cell carcinoma (HNSCC). However, little evidence supports which smoking metric best models the association between smoking and survival in HNSCC. Objective: To determine which …

us (code pays fourni par la source)

Performance of 8 Smoking Metrics for Modeling Survival in Head and Neck Squamous Cell Carcinoma

Andrew C. L. Lam, Katrina Hueniken, Martha Pienkowski, Jong Wook Lee et autres

Importance: Cigarette smoking is a strong risk factor for mortality in patients diagnosed with head and neck squamous cell carcinoma (HNSCC). However, little evidence supports which smoking metric best models the association between smoking and survival in HNSCC. Objective: To determine which …

ca, us, fr, de, gb, gr, it, es, ie, no, cz (code pays fourni par la source)

Understanding the biological processes of kidney carcinogenesis: an integrative multi-omics approach

Ricardo Cortez Cardoso Penha, Alexandra Sexton Oates, S. Senkin, Hanla A. Park et autres

Biological mechanisms related to cancer development can leave distinct molecular fingerprints in tumours. By leveraging multi-omics and epidemiological information, we can unveil relationships between carcinogenesis processes that would otherwise remain hidden. Our integrative analysis of DNA methylome, transcriptome, and somatic mutation profiles …

fr, gb, cz, vn, rs, pl, hu, ru, sg (code pays fourni par la source)

Transcriptome- and proteome-wide association studies identify genes associated with renal cell carcinoma

Diptavo Dutta, Xinyu Guo, Timothy Winter, Om Jahagirdar et autres

us (code pays fourni par la source)

Geographic variation of mutagenic exposures in kidney cancer genomes

S. Senkin, Sarah Moody, Marcos Díaz‐Gay, Behnoush Abedi‐Ardekani et autres

Abstract International differences in the incidence of many cancer types indicate the existence of carcinogen exposures that have not yet been identified by conventional epidemiology make a substantial contribution to cancer burden 1 . In clear cell renal cell carcinoma, obesity, hypertension …

fr, gb, us, tr, ir, th, pl, lt, jp, la, ro, rs, ca, br, ru, pt, cz, no, sg, nl (code pays fourni par la source)

Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions

Mark P. Purdue, Diptavo Dutta, Mitchell J. Machiela, Bryan R. Gorman et autres

us, fr, fi, gb, br, id, jp, ca, uy, sg, cz, la, ro, rs, pt (code pays fourni par la source)

Disease aetiology and progression shape the inter-patient multi-omics profile of clear cell renal carcinoma

Ricardo Cortez Cardoso Penha, Alexandra Sexton‐Oates, S. Senkin, Hanla A. Park et autres

fr, gb, cz, pl, ru, ch (code pays fourni par la source)

Geographic variation of mutagenic exposures in kidney cancer genomes

S. Senkin, Sarah Moody, Marcos Díaz‐Gay, Behnoush Abedi‐Ardekani et autres

ABSTRACT International differences in the incidence of many cancer types indicate the existence of carcinogen exposures that have not been identified by conventional epidemiology yet potentially make a substantial contribution to cancer burden 1 . This pertains to clear cell renal cell …

fr, gb, us, tr, ir, th, pl, lt, am, jp, la, ro, rs, ch, ca, br, ru, pt, cz, vn, no, sg, nl (code pays fourni par la source)