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Profil bibliographique

Jan L Nouwen

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

78Publications signalées
6220Citations signalées
2Affiliations récentes

Les institutions déclarées

Les domaines associés

Antimicrobial Resistance in StaphylococcusHIV/AIDS drug development and treatmentBacterial Identification and Susceptibility TestingHIV-related health complications and treatmentsHIV/AIDS Research and Interventions

Les publications récentes

Accès ouvert 2026 article OpenAlex

Transition of oral microbiome profile in HIV-infected Indonesian patients: the role of antiretroviral therapy

Muhammad Anshory, Nikolaos Strepis, John Philip Hays, Milanitalia Gadys Rosandy et autres

Background HIV infection alters host immunity, including the oral environment, leading to microbial imbalance and increased risk of opportunistic infections. Although antiretroviral therapy (ART) improves immune function, its effect on the oral microbiome remains unclear, particularly in Indonesia. This study investigated oral …

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0 citations Journal of Oral Microbiology
Accès ouvert 2025 article OpenAlex

Association of ABO Blood Groups with Dengue Fever and its Severity: A Study in Surabaya, Indonesia

Sulistiawati Sulistiawati, Linda Dewanti, Ronald Pratama Adiwinoto, Raissa Manika Purwaningtias et autres

Background: Indonesia, a dengue-endemic country, has high morbidity and mortality rates. Dengue infection manifestations vary from asymptomatic to mild to severe. One of the risk factors for infection that plays a role in this severity is blood type. A better understanding of …

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0 citations Journal of Health Research
Accès ouvert 2025 article OpenAlex

Risk of new HIV diagnosis by intersecting migration, socioeconomic, and mental health vulnerabilities in the Netherlands: a nationwide analysis of the ATHENA cohort and Statistics Netherlands registry data

Vita Willemijn Jongen, Anders C. Boyd, Patrizia Carrieri, Nina Schat et autres

Background: To further reduce new HIV diagnoses in the Netherlands, individual and structural barriers hindering prevention must be addressed. We aimed to estimate the disproportional burden of new HIV diagnoses and explore how intersecting socio-demographic, socio-economic, and health-related factors jointly influence the …

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1 citation The Lancet Regional Health - Europe
Accès ouvert 2025 article OpenAlex

Global health at crossroads: uniting together to overcome challenges, restore trust and advance priorities for a sustainable future

Massimo Sartelli, Elias A. Mossialos, Federico Coccolini, Ib Jammer et autres

The world is currently facing an unprecedented convergence of crises that threaten the core pillars of public health, scientific integrity, and social stability. These challenges are profoundly interconnected and have the potential to exacerbate global inequalities, jeopardize health security, and undermine the …

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10 citations World Journal of Emergency Surgery
Accès ouvert 2025 review OpenAlex

Dermatological manifestation of HIV infection: systematic review and meta-analysis

Muhammad Anshory, Raden Mohamad Rendy Ariezal Effendi, Milanitalia Gadys Rosandy, Handono Kalim et autres

Since its discovery in 1981, AIDS has become a significant global public health issue, impacting more than 38 million people worldwide with HIV. Despite a 32% reduction in new HIV infections since 2010, millions continue to be affected, often experiencing dermatological problems. …

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7 citations BMC Infectious Diseases
Accès ouvert 2025 article OpenAlex

Cerebral toxoplasmosis in the twenty-first century

Charlotte M. van Deuzen, Bart J. A. Rijnders, Hannelore I. Bax, Casper Rokx et autres

BACKGROUND: Cerebral toxoplasmosis is a common opportunistic infection in people with HIV (PWH), associated with high morbidity and mortality. It is unclear how clinical characteristics, treatment response and long-term clinical outcomes in PWH with cerebral toxoplasmosis have changed due to improved treatment …

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1 citation AIDS
Accès ouvert 2025 article OpenAlex

HIV-Associated Dermatological Alterations: Barrier Dysfunction, Immune Impairment, and Microbiome Changes

Muhammad Anshory, Handono Kalim, Jan L Nouwen, Hok Bing Thio

Human Immunodeficiency Virus (HIV) significantly impacts skin structure, immune responses, and the microbiome, contributing to diverse dermatological conditions. The epidermis, a key physical and immunological barrier, undergoes structural changes such as hyperplasia and inflammatory infiltrates. Skin adnexal structures like hair follicles also …

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7 citations International Journal of Molecular Sciences
Accès ouvert 2024 article OpenAlex

Trends in Mortality in People With HIV From 1999 through 2020: A Multicohort Collaboration

Erich S. Tusch, Lene Ryom, Annegret Pelchen–Matthews, Amanda Mocroft et autres

BACKGROUND: Mortality among people with human immunodeficiency virus (HIV) declined with the introduction of combination antiretroviral therapy. We investigated trends in mortality in people with HIV from 1999 through 2020. METHODS: Data were collected from the Data Collection on Adverse events of …

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31 citations Clinical Infectious Diseases
Accès ouvert 2023 article OpenAlex

The BAF complex inhibitor pyrimethamine reverses HIV-1 latency in people with HIV-1 on antiretroviral therapy

Henrieke A. B. Prins, Raquel Crespo, Cynthia Lungu, Shringar Rao et autres

Reactivation of the latent HIV-1 reservoir is a first step toward triggering reservoir decay. Here, we investigated the impact of the BAF complex inhibitor pyrimethamine on the reservoir of people living with HIV-1 (PLWH). Twenty-eight PLWH on suppressive antiretroviral therapy were randomized …

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13 citations Science Advances
Accès ouvert 2023 article OpenAlex

Butyrate Properties in Immune-Related Diseases: Friend or Foe?

Muhammad Anshory, Raden Mohamad Rendy Ariezal Effendi, Handono Kalim, Reiva Farah Dwiyana et autres

Butyrate is a short-chain fatty acid (SCFA) created within the intestinal lumen by bacterial fermentation of largely undigested dietary carbohydrates. Its beneficial effects on cellular energy metabolism and intestinal homeostasis have garnered significant attention among SCFAs. Butyrate also has systemic effects and …

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49 citations Fermentation
Accès ouvert 2023 article OpenAlex

External validation of the PAGE-B score for HCC risk prediction in people living with HIV/HBV coinfection

Bernard Surial, Adrià Ramírez Mena, Marie Roumet, Andreas Limacher et autres

BACKGROUND & AIMS: HBV coinfection is common among people living with HIV (PLWH) and is the most important cause of hepatocellular carcinoma (HCC). While risk prediction tools for HCC have been validated in patients with HBV monoinfection, they have not been evaluated …

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17 citations Journal of Hepatology
Accès ouvert 2022 preprint OpenAlex

The BAF complex inhibitor pyrimethamine reverses HIV-1 latency in people with HIV-1 on antiretroviral therapy

Henrieke A. B. Prins, Raquel Crespo, Cynthia Lungu, Shuan Rao et autres

Abstract A major barrier towards HIV-1 cure is the presence of a replication-competent latent reservoir that, upon treatment cessation, can spark viral rebound leading to disease progression. Pharmacological reactivation of the latent HIV-1 reservoir with Latency reversing agents (LRAs) is a first …

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1 citation medRxiv

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