Ayşegül Aktaş

Prognostic Factors Affecting Ipsilateral Breast Tumor Recurrence in Breast-Conserving Surgery

Ayşegül Aktaş

Introduction: Breast cancer is the most common malignancy among women worldwide.Breast-conserving surgery (BCS) is the standard surgical treatment for patients with early-stage breast cancer.Fear of recurrence strongly influences surgical decision-making and significantly impacts the long-term quality of life in breast cancer survivors.The …

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Role of Sentinel Lymph Node Biopsy with Blue Dye Only after Neoadjuvant Systemic Treatment in Patients with Breast Cancer Who Had Biopsy-Proven Node-Positive Disease at Admission: SENATURK-ROSANNA Study

Ayşegül Aktaş, Meryem Günay Gürleyik, Güldeniz Karadeniz Çakmak, Hasan Karanlık et autres

Introduction: In breast cancer patients with initially metastatic axillary lymph nodes (pN+, ALNs), neoadjuvant systemic treatment (NST) significantly downstages axillary disease. Sentinel lymph node biopsy (SLNB) in well-responded patients has been associated with high false-negative rates (FNRs) when less than 3 nodes …

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Causes of diagnostic and treatment delays in locally advanced breast cancer: a nationwide multicenter survey and electronic health records analysis in Turkiye

Güldeniz Karadeniz Çakmak, Ufuk Tali, Hakan Balbaloĝlu, İlhan Taşdöven et autres

Delays in breast cancer (BC) diagnosis and treatment negatively impact survival outcomes. Understanding patient- and provider-related factors behind these delays is crucial. This study aimed to identify nationwide reasons for delayed diagnosis and treatment of locally advanced BC in Turkiye. A prospective, …

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Invasive lobular breast carcinoma variants; clinicopathological features and patient outcomes

Ayşegül Aktaş, Meryem Günay Gürleyik, Doğukan Akkuş, Zekeriya Ucur et autres

INTRODUCTION: An understanding of the differences among the invasive lobular breast carcinoma (ILC) variants is crucial for risk stratification, and tailored treatment planning. This article compares variants of ILC according to their clinical outcomes and histopathological features. PATIENTS AND METHODS: Patients diagnosed …

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Splenic abscess: treatment options in a disease with high mortality

Kadir Çorbacı, Günay Gürleyik, Ayşegül Aktaş

BACKGROUND: Spleen abscess is a rare and serious condition. Splenectomy and imaging-guided percutaneous catheter drainage (PCD) are the methods used in the treatment, but there is still a debate about the appropriate treatment for the patient. METHODS: The results of 16 patients …

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¿La quimioterapia neoadyuvante proporciona algún beneficio para la desescalada quirúrgica en el cáncer de mama HER2(Ó?) luminal B?

Ayşegül Aktaş, Elif Atağ, Fügen Aker, Meryem Gunay-Gurleyik et autres

BACKGROUND: The use of neoadjuvant chemotherapy (NAC) in less aggressive breast cancer (BC) is controversial. OBJECTIVE: To investigate the effect of neoadjuvant chemotherapy in HER2 negative luminal B breast cancer. PATIENTS AND METHODS: Patients between January 2016 and December 2021 were retrospectively …

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Aile Hekimliğinde Güncel Yaklaşımlar

Mina Lara Akıncı, Cemil Işık Sönmez, Eda Kuran, Zerrin Gamsızkan et autres

Aile hekimliği tıp disiplinin özelliklerini, ilkelerini ve temel değerlerini detaylarıyla bulabileceğiniz bölümlerin yanında, klinik uygulamalarda izlenecek yollar ve kılavuzların eşlik ettiği güncel bilgileri sizlerle paylaşmayı hedefledik. Aile hekimliğinin, yaş, cinsiyet, hastalık ayırt etmeksizin sunduğu sağlık bakımına ek olarak koruyucu sağlık hizmetlerinin prekonsepsiyonel …

Diagnostic Value of Axillary Ultrasound, MRI, and 18F-FDG-PET/ CT in Determining Axillary Lymph Node Status in Breast Cancer Patients

Ayşegül Aktaş, Günay Gürleyik, Sibel Aydın Aksu, Fügen Aker et autres

Objective: Knowing axillary lymph node (ALN) status before surgery affects decisions about treatment modalities.Therefore, reliable, noninvasive diagnostic methods are important for determining ALN metastases.We aimed to accurately evaluate the patient's ALN status with noninvasive imaging modalities while making treatment decisions. Materials and …

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Pathological Complete Response to Neoadjuvant Chemotherapy in Patients With Breast Cancer: The Relationship Between Inflammatory Biomarkers and Molecular Subtypes

Günay Gürleyik, Ayşegül Aktaş, Fügen Aker, Eda Tanrıkulu et autres

Purpose Among patients with breast cancer, pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) is an important prognostic predictor of survival. This study aimed to investigate the relationship between platelet-lymphocyte ratio (PLR) and neutrophil-lymphocyte ratio (NLR) along with overall pCR. Method A …

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Correlations of Primary Tumor SUVmax and Axillary Lymph Node SUVmax with Molecular Subtypes of Invasive Breast Cancer

Ayşegül Aktaş, Selda Oğuz Aşlayan, Meryem Günay Gürleyik, Serkan Güngör

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acil servise vertigo ile başvuran hastaların prospektif incelenmesi

VAHİDE ASLIHAN DURAK, ŞULE AYDIN, Ayşegül Aktaş

Are BRAF V600E and K-Ras Mutations Associated With Tumor Aggressiveness in Well-Differentiated Thyroid Cancer?

Mutlu Ünver, Özer Makay, Aslı Kısım, Gülruh Emiroğlu et autres

Aim: Many clinical studies have shown an association between B-type rapidly growing fibrosarcoma kinase [BRAF(V600E)] mutation and aggressive clinicopathologic features, although some results from others are controversial. Besides, Kirsten rat sarcoma (K-Ras) mutations are more common in endemic iodine deficiency regions, as …