Young Ran Kim

Association of miRNA (miR-10a, miR-30c, miR-181a, and miR-499b) Polymorphisms and Their Interactions with PAI-1 in Recurrent Implantation Failure in Korean Women

Hui Jeong An, Sung Hwan Cho, Ji Eun Ko, Ji Hyang Kim et autres

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Development and Effects of an Early Childhood Upcycling Program Based on Maker Education

Young Ran Kim

본 연구는 메이커교육을 적용한 유아 업사이클링 교육 프로그램을 개발하고, 그 효과를 검증하는 데 목적이 있다. 프로그램은 기후위기와 지속가능발전교육의 관점을 바탕으로 유아 업사이클링 교육을 중심으로 구성하였으며, 메이커교육은 프로그램 실행을 위한 교수·학습방법으로 적용하였다. 프로그램 개발을 위해 기후위기와 지속가능발전교육, 유아 환경교육, 업사이클링 교육, 메이커교육 및 …

Placental Growth Factor Secreted from Placenta-Derived Mesenchymal Stem Cells Improves Ovarian Function in TAA-Injured Rats via Antioxidant Effects

Jae-Young Shin, Dae-Hyun Lee, Hyeri Park, Young Ran Kim et autres

Ovarian dysfunction resulting from metabolic or toxic injury is characterized by follicular depletion, stromal remodeling, oxidative stress, and endocrine dysregulation. Placenta-derived mesenchymal stem cells (PD-MSCs) have been proposed as a potential therapeutic approach due to their paracrine factors, including placental growth factor …

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Mechanism by which a linoleic acid metabolite suppresses cancer cell growth by inhibiting mTOR

Seung Ju Park, Sera Kim, Hongmok Kwon, Jiyeon Choi et autres

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Postpartum Eclampsia Complicated With Posterior Reversible Encephalopathy Syndrome: 2 Case Reports

Min Jeong Kwak, Eun Hee Ahn, Young Ran Kim

Hypertensive disorders during pregnancy can lead to postpartum eclampsia and neurological complications such as posterior reversible encephalopathy syndrome (PRES). We report 2 cases of postpartum eclampsia in twin pregnancies, both presenting with seizures following acute blood pressure elevation after cesarean delivery. Brain …

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Association Study of Hyaluronan-Binding Protein 2 (HABP2) Gene Polymorphisms in Idiopathic Recurrent Pregnancy Loss (RPL) in Korean Women

Jeong Yong Lee, Young Ran Kim, Eun Ju Ko, Hyeon Woo Park et autres

Recurrent pregnancy loss (RPL), also termed recurrent spontaneous abortion, is defined as the failure of ≥2 consecutive pregnancies before 20 weeks of gestation. Approximately 5% of pregnant couples experience RPL. The hyaluronan-binding protein 2 (HABP2) gene is involved in coagulation and plays …

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Epigenome-wide profiling of trisomy 18 specific DNA methylation signatures in first-trimester chorionic villi

Ju Yeon Kim, Yang Su, Jin‐Woo Kim, Yong Jun Choi et autres

BACKGROUND: Trisomy 18 (T18, Edwards syndrome) is a lethal chromosomal disorder characterized by multiple congenital anomalies and high perinatal mortality. Although epigenetic alterations have been described in aneuploidy conditions, their causal role in the pathogenesis of T18 remains unclear. This study aimed …

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Early Pregnancy Nutritional Adequacy and Subsequent Gestational Diabetes Risk by Body Mass Index: A Prospective Cohort Study of 2227 Korean Women

Hye-Ji Han, Hyun Jung Lee, Jin Woo Kim, Sun Young Yang et autres

Background/Objectives: This study evaluated the association between nutrient intake adequacy during early pregnancy and gestational diabetes mellitus (GDM) risk through a prospective cohort study of Korean pregnant women. Methods: A total of 2227 singleton pregnant women were included in this study. Dietary …

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Optimization of a porous polycaprolactone coating to enhance the mechanical properties and bioactivity of an additively manufactured hydroxyapatite scaffold

Seyed Aliakbar Hosseini Toopghara, Young-Ook Hwang, Ye Seul Kim, Young Ran Kim et autres

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Genetic Associations of ITGB3, FGG, GP1BA, PECAM1, and PEAR1 Polymorphisms and the Platelet Activation Pathway with Recurrent Pregnancy Loss in the Korean Population

Eun Ju Ko, Eun Hee Ahn, Hyeon Woo Park, Jae‐Hyun Lee et autres

Recurrent pregnancy loss (RPL) is defined as the occurrence of two or more pregnancy losses before 20 weeks of gestation. RPL is a common medical condition among reproductive-age women, with approximately 23 million cases reported annually worldwide. Up to 5% of pregnant …

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BACES score: a predictor of health-related quality of life and associated factors in patients with nontuberculous mycobacterial pulmonary disease

Youngmok Park, Nakwon Kwak, Hyeontaek Hwang, Doosoo Jeon et autres

The evaluation of health-related quality of life (HRQOL) is gaining importance among patients with nontuberculous mycobacterial pulmonary disease (NTM-PD). We assessed whether the BACES score reflects HRQOL and associated factors in these patients. Data were collected from the nationwide NTM-KOREA prospective cohort …

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Genetic Association of PCSK5 and MUC2 Gene Polymorphisms with Recurrent Pregnancy Loss (RPL)

Chang Soo Ryu, Ji Hyang Kim, Eun Ju Ko, Hyeon Woo Park et autres

Recurrent pregnancy loss (RPL) is defined as the occurrence of two or more consecutive pregnancy losses before 20 weeks of gestation, encompassing both embryonic and fetal losses. Although previous studies have provided substantial insights into RPL, the causes in many cases remain …

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