Cody J. Tragesser

Early-onset inflammatory bowel disease: progress and persistent inequities

Cody J. Tragesser, Abel G. Joy, Chhinder P. Sodhi

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Lipid-fortified diets protect against intestinal inflammation and dysmotility in neonatal mice

Chhinder P. Sodhi, Cody J. Tragesser, Daniel J. Scheese, Johannes Wolfgang Duess et autres

Abstract Newborn infants are at increased risk of gastrointestinal dysfunction, inflammation, and feeding intolerance because their digestive and immune systems are not fully developed. BioLipids-fortified diets enriched with a blend of medium-chain triglycerides (MCTs), mono- and diglycerides (MDGs), and milk phospholipids (MPLs) …

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Transcutaneous auricular vagus nerve stimulation attenuates neuroinflammation in a mouse model of traumatic brain injury

Mahmoud G. El Baassiri, Leonard Lawandos, Daniel J. Scheese, Cody J. Tragesser et autres

INTRODUCTION: Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Although TBI pathophysiology has been thoroughly investigated, the effectivity of therapeutic approaches for TBI is still lacking. Our group has developed a novel approach of noninvasive transcutaneous auricular …

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Maternal nicotine vaping activates neonatal innate immunity in mice 3745

Sierra Williams-McLeod, Aishat Fagun, A. James Mason, Koichi Tsuboi et autres

Abstract Description Electronic cigarettes, also known as e-cigarettes or vapes, are battery-operated devices that heat and produce aerosols for inhalation. Maternal nicotine e-cigarette use during pregnancy can have detrimental effects on fetal growth and development, which may be in part due to …

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Beyond aganglionosis: BCL-2 and Laminin signatures Elucidate Hirschsprung disease and Hirschsprung-Associated Enterocolitis pathogenesis

Cody J. Tragesser, Chhinder Pal Sodhi

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Robotic Heller myotomy and fundoplication - techniques and outcomes

Daniel J. Scheese, Cody J. Tragesser, Tejal Patki, Carlos A. Puig et autres

Achalasia, a primary esophageal motility disorder characterized by impaired peristalsis and the inability of the lower esophageal sphincter to relax, affects approximately 0.5-1.2 individuals per 100,000 annually. Traditional treatments have included endoscopic interventions and Heller myotomy with partial fundoplication, long regarded as …

Necrotizing Enterocolitis: A Comprehensive Review on Toll-like Receptor 4-Mediated Pathophysiology, Clinical, and Therapeutic Insights

Asuka Ishiyama, Hee‐Seong Jang, Jay M. Dintaman, Johannes Wolfgang Duess et autres

This review integrates clinical, immunological, microbial, pathophysiological, and therapeutic perspectives on necrotizing enterocolitis (NEC)-a leading cause of morbidity and mortality in premature infants. We summarize the clinical burden and risk factors; elucidate key immune and cellular mechanisms, including TLR4 signaling, epithelial barrier …

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Intestinal Dysmotility and the Risk of Volvulus Following Omega-Jejunostomy Tube Placement in Children

Daniel J. Scheese, Charbel Chidiac, Cody J. Tragesser, Erica Hodgman et autres

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Necrotizing enterocolitis: specific human milk oligosaccharides prevent enteric glia loss and hypomotility

Chhinder Pal Sodhi, Daniel J. Scheese, Cody J. Tragesser, William B. Fulton et autres

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Cytomegalovirus Worsens Necrotizing Enterocolitis Severity in Mice via Increased Toll-Like Receptor 4 Signaling

Daniel J. Scheese, Peng Lü, Hannah Moore, Koichi Tsuboi et autres

BACKGROUND AND AIMS: Necrotizing enterocolitis (NEC) is a life-threatening condition in premature infants, marked by acute intestinal necrosis. NEC develops in part after activation of the lipopolysaccharide receptor toll-like receptor 4 (TLR4) by intestinal microbes in the intestinal epithelium. Previous authors have …

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Choosing a Good Scientific Mentor and Being a Good Mentee

Cody J. Tragesser, Daniel J. Scheese, Mark L. Kovler, Benjamin D. Shogan et autres

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Learning Curve and Patient Outcomes of Minimally Invasive Esophagectomy: One Surgeon’s 10-Year Experience

Chehab, Moamad, M.D., Cody J. Tragesser, Geroudis, Franklin, M.D., Rebecca Deitch et autres

Objective: To examine the learning curve of one surgeon performing minimally invasive esophagectomy (MIE) over a 10-year period since the beginning of their practice with a focus on patient outcomes. Methods: This is a retrospective study of all patients undergoing MIE for …

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