Abstract 1699: GlycoConnect© ADC toolbox expansion with dual payload ADC (dpADC) technology
Remon van Geel, Lieke Kraaijvanger, Mick Verhagen, Nick Burgers et autres
0 citationsCancer Research
Marcel Scheepstra
Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.
18Publications signalées
449Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
Nuclear Receptors and SignalingEstrogen and related hormone effectsUbiquitin and proteasome pathwaysRetinoids in leukemia and cellular processesHER2/EGFR in Cancer Research
Publications récentes
Abstract 1682: Potency-Attenuated analogues of PNU-159,682 in conjugation with GlycoConnect® and HydraSpace® technologies provide ADCs with improved tolerability and efficacy
Marcel Scheepstra, Remon van Geel, Jorin Hoogenboom, Lianne P. W. M. Lelieveldt et autres
0 citationsCancer Research
Abstract 4690: SC-2882, a novel QPCTL inhibitor, with anti-tumor activity in solid tumor models
Jasper Mullenders, Marcel Scheepstra, Michel R. Faas, Annette B. Galler et autres
0 citationsCancer Research
Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen
Koen F. W. Hekking, Sergio Maroto, Kees van Kekem, Frank S. Haasjes et autres
11 citationsJournal of Medicinal Chemistry
Qpctl Inhibition, By Targeting the Inflammatory Tumor Microenvironment, Constitutes a Novel Therapeutic Approach for Diffuse Large B-Cell Lymphoma
Nicolás Di Siervi, Jasper Mullender, María V. Revuelta, Nahuel Zamponi et autres
3 citationsBlood
Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists
Femke A. Meijer, Richard G. Doveston, R.M.J.M. de Vries, Gaël M. Vos et autres
38 citationsJournal of Medicinal Chemistry
Bivalent Ligands for Protein Degradation in Drug Discovery
Marcel Scheepstra, Koen F. W. Hekking, Luc Van Hijfte, R.H.A. Folmer
117 citationsComputational and Structural Biotechnology Journal
Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization
Marcel Scheepstra, Sebastian A. Andrei, R.M.J.M. de Vries, Femke A. Meijer et autres
27 citationsACS Chemical Neuroscience
Designed Spiroketal Protein Modulation
Marcel Scheepstra, Sebastian A. Andrei, M. Yağız Ünver, Anna K. H. Hirsch et autres
14 citationsAngewandte Chemie International Edition
Designed Spiroketal Protein Modulation
Marcel Scheepstra, Sebastian A. Andrei, M. Yağız Ünver, Anna K. H. Hirsch et autres
1 citationAngewandte Chemie
Crystal structure of the Retinoid X Receptor alpha in complex with synthetichonokiol derivative 3 and a fragment of the TIF2 co-activator.
Sebastian A. Andrei, Luc Brunsveld, Marcel Scheepstra, Christian Ottmann
0 citationsWorldwide Protein Data Bank
Chiral Dihydrobenzofuran Acids Show Potent Retinoid X Receptor–Nuclear Receptor Related 1 Protein Dimer Activation
Henrik Sundén, Anja Schäfer, Marcel Scheepstra, S. Leysen et autres
19 citationsJournal of Medicinal Chemistry
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