Sara L. Kroll

Endocannabinoid response to social stress in chronic non-medical prescription opioid users

Vinzenz K. Schmid, Boris B. Quednow, Daniele Pellegata, Philip Meier et autres

Endocannabinoid response to social stress in chronic non-medical prescription opioid users

Boris B. Quednow, Daniele Pellegata, Philip Meier, Jürg Gertsch et autres

RATIONALE: The ongoing global opioid crisis underscores the need to better understand the neurobiological mechanisms underlying opioid use disorder (OUD). Stress is a key risk factor for developing and maintaining OUD. While animal models report that the endocannabinoid system (ECS) plays a …

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622. The Role of the Endocannabinoid System in Social Stress Reactivity Among Non-Medical Prescription Opioid Users

Boris B. Quednow, Philip Meier, Sara L. Kroll

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Changes in peripheral endocannabinoid levels in substance use disorders: a review of clinical evidence

Grace Elliott, Gavin N. Petrie, Sara L. Kroll, Daniel J O Roche et autres

The endocannabinoid (eCB) system is a key modulator of stress and reward and is impacted by alcohol and drug use. Recently, the eCB system has been highlighted as a potential novel target in the treatment of substance use disorders (SUDs). Understanding how …

Changes in peripheral endocannabinoid levels in substance use disorders: a review of clinical evidence

Grace Elliott, Gavin N. Petrie, Sara L. Kroll, Daniel Roche et autres

Background: The endocannabinoid (eCB) system is a key modulator of stress and reward and is impacted by alcohol and drug use. Recently, the eCB system has been highlighted as a potential novel target in the treatment of substance use disorders (SUDs).Objectives: Understanding …

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Anandamide and anxiety

Sara L. Kroll, Leah M. Mayo

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Contributors

Yalitza Azucena Alvarado Ramírez, Balapal S. Basavarajappa, Sheldon Bereznick, Laura M. Best et autres

https://doi.org/10.1016/b978-0-443-19081-0.01002-7

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Endocannabinoids and related lipids linked to social exclusion in individuals with chronic non-medical prescription opioid use

Sara L. Kroll, Philip Meier, Leah M. Mayo, Jürg Gertsch et autres

Opioid-related overdose deaths are still on the rise in North America, emphasizing the need to better understand the underlying neurobiological mechanisms regarding the development of opioid use disorder (OUD). Recent evidence from preclinical and clinical studies indicate that the endocannabinoid system (ECS) …

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Plasma endocannabinoids in cocaine dependence and their relation to cerebral metabotropic glutamate receptor 5 density

Sara L. Kroll, Lea M. Hulka, Ann-Kathrin Kexel, Matthias Vonmoos et autres

Abstract Animal models indicate that the endocannabinoid system (ECS) plays a modulatory role in stress and reward processing, both crucially impaired in addictive disorders. Preclinical findings showed endocannabinoid-modulated synaptic plasticity in reward brain networks linked to the metabotropic-glutamate-5 receptor (mGluR5), contributing to …

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Plasma endocannabinoids in cocaine dependence and their interaction with cocaine craving and metabotropic glutamate receptor 5 density in the human brain

Sara L. Kroll, Lea M. Hulka, Ann-Kathrin Kexel, Matthias Vonmoos et autres

ABSTRACT Animal models indicate that the endocannabinoid system (ECS) plays a modulatory role in stress and reward processing, both crucially impaired in addictive disorders. Preclinical findings showed endocannabinoid-modulated synaptic plasticity in reward brain networks linked to the metabotropic-glutamate-5 receptor (mGluR5), contributing to …

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Buprenorphine and error processing

Markus Rütgen, Daniela M. Pfabigan, I Riečanský, Sara L. Kroll et autres

EEG study investigating whether the opioid buprenorphine influences behavioural and neural measures of error processing.

P.0618 Chronic cocaine users show altered glucocorticoid and endocannabinoid levels in hair

Sara L. Kroll, Clarissa D. Voegel, Megan J. Schmid, Ann-Kathrin Kexel et autres

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