Juan Pineda-Reyes

A surprising diagnosis of paracoccidioidomycosis from routine bacterial culture of chronic finger lesions

Nikita Jaggernauth, Juan Pineda-Reyes, Claire Zurlo, Devin Weber et autres

ABSTRACT Background Paracoccidioidomycosis is a systemic mycosis endemic to Central and South America. Here, we describe an unusual case of an elderly female with cutaneous paracoccidioidomycosis and comorbidities limiting the use of first-line therapeutic agents. Case Summary An 89-year-old female with a …

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Case Report: Myeloid neoplasms with the t(3;12)(q26.2;p13.1)/MECOM-ETV6 translocation: report of two new cases and review of the literature

Soumya Mikkilineni, Juan Pineda-Reyes, Lindsay Wilde, Andres Ferbér et autres

The MECOM (MDS1 and EVI1 complex locus) gene, located at 3q26.2, encodes an oncogenic transcription factor implicated in multiple signaling pathways. Rearrangements involving MECOM/3q26.2, including inversions, translocations, insertions and cryptic chromosomal changes, are observed in myeloid neoplasms and are associated with high-risk …

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The Presence of Pigment Incontinence in Sinonasal Mucosal Melanoma

Shreya Mandloi, Stacey Gargano, Alexander Duffy, Peter A. Benedict et autres

BACKGROUND: Regression is an immunological phenomenon described in cutaneous melanoma whereby tumor is replaced with tumor-infiltrating lymphocytes, granulation tissue, and mature fibroblasts often accompanied by pigment incontinence (accumulation of melanin in the upper dermis). Pigment incontinence results in grossly pigmented lesions that …

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Dual PD-L1/SOX10 Immunohistochemistry Combined With Digital Imaging Enhances Stratification Accuracy of Patients With Metastatic Melanoma

Juan Pineda-Reyes, Sri Krishna Chaitanya Arudra, Phyu P. Aung, Priyadharsini Nagarajan et autres

Immune checkpoint inhibitor therapy has demonstrated an overall survival benefit in patients with advanced melanoma. Though the significance of programmed death-ligand 1 (PD-L1) expression on melanoma cells as a predictive biomarker of response remains inconclusive, some reports indicate that a PD-L1 expression …

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P121: Myeloid neoplasms with the t(3;12)(q26.2;p13)/MECOM-ETV6 translocation: Report of two new cases and review of the literature

Soumya Mikkilineni, Juan Pineda-Reyes, Lin Wang, Dorothy Foster et autres

The MECOM (MDS1 and EVI1 complex locus) gene is located at 3q26.2, encoding a proto-oncogenic transcription factor involved in the RAS/receptor tyrosine kinase pathway. Rearrangements involving MECOM/3q26.2, such as inversion, translocation, insertion and cryptic chromosomal changes, have been observed in acute myeloid …

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Comparación de la eficacia y toxicidad del estibogluconato de sodio y antimoniato de meglumina en el tratamiento de leishmaniasis cutánea en Perú

Alejandro Llanos‐Cuentas, Juan Pineda-Reyes, Fiorela Alvarez, Ana Pilar Ramos et autres

Objetivos: Comparar la eficacia y toxicidad del antimoniato de meglumina (AM) y estibogluconato sódico (EGS) en el tratamiento de leishmaniasis cutánea (LC) en un hospital general. Material y métodos: Serie de casos comparativa de 193 pacientes con LC tratados en tres ensayos …

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Perfil inmunofenotípico de cáncer de mama de pacientes atendidas en un hospital general de Lima, Perú

Jorge Emerson Chachaima-Mar, Juan Pineda-Reyes, R. Cabrera Marín, Zenaida Lozano-Miranda et autres

La inmunohistoquímica permite clasificar al cáncer de mama en subtipos que tienen relevancia para el tratamiento y pronóstico. En comparación con los marcadores genéticos, la inmunohistoquímica es de costos accesibles, más fácil de realizar y tiene buena correlación con los subtipos moleculares. …

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Manipulación de lesiones en pacientes con leishmaniasis cutánea: serie de casos en un hospital peruano

Juan Pineda-Reyes, Ricardo Marín, Andrea Tinageros-Zevallos, Ana Pilar Ramos et autres

In cutaneous leishmaniasis endemic areas it is a common practice for patients to manipulate their lesions with traditional treatments as a first therapeutic option. A case series study was conducted in order to describe the frequency and the variations of the patient …

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Strongyloides stercoralis hyperinfection syndrome: a deeper understanding of a neglected disease

George Vasquez‐Rios, Roberto Pineda-Reyes, Juan Pineda-Reyes, Ricardo Marín et autres

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