Stefan Vogt

Acquisition Geometry-Assisted Whole-Group Localization of X-ray Fluorescence Maps in Optical Microscopy Images

Xiangyu Yin, Tatjana Paunesku, Letonia Copeland-Hardin, Martina Ralle et autres

X-ray fluorescence (XRF) microscopy maps elemental distributions, while optical microscopy can provide complementary morphological context. Localizing XRF fields of view (FOVs) in optical images is difficult because the two modalities differ in contrast mechanism and resolution. Most current workflows place each XRF …

XRF-to-Optical Field-of-View Localization with Vision Language Models

Xiangyu Yin, Tatjana Paunesku, Letonia Copeland-Hardin, Martina Ralle et autres

Registering images acquired with different microscopy modalities is essential for relating complementary measurements of the same specimen. In correlative X-ray fluorescence (XRF) and optical microscopy, the XRF map often covers only a small region of an optical image acquired from the same …

Lysosomal Expansion Compartments Mediate Zinc and Copper Homeostasis in Caenorhabditis elegans

Joy R Armendariz, Sean Teng, Camdyn Rakow, Raquel Herrera et autres

, excess zinc is stored in lysosomes in intestinal cells; this process involves increasing the expression of the zinc transporter CDF-2 and remodeling of lysosomes characterized by an increase in the volume of the expansion compartment. To determine if this is a …

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Supplementary Data from Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematologic Cancers and Identifies Exceptional Responders

Christoph Kornauth, Tea Pemovska, Gregory I. Vladimer, Günther Bayer et autres

Supplementary Data containing the statistical analysis plan, Supplemental Figures 1-6 and Supplemental Tables 1 and 2

Die Rolle des Öffentlichen Gesundheitsdienstes bei der Verstetigung von »LIEBESLEBEN – Das Mitmach-Projekt« – Ein Projekt zur Förderung sexueller Gesundheit im Setting Schule

S. Richter, Sarah Halbach, Dieter Meyer, Stefan Vogt

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Endothelial Cu Uptake Transporter CTR1 Senses Disturbed Flow to Promote Atherosclerosis through Cuproptosis

Sudhahar Varadarajan, Zhen Xiao, Archita Das, Dipankar Ash et autres

Endothelial cells (ECs) lining blood vessels sense disturbed blood flow (D-flow), which drives mitochondrial dysfunction and atherosclerosis. Copper (Cu) is an essential micronutrient, and its disruption of homeostasis has been implicated in atherosclerosis. Cellular Cu levels are tightly controlled by Cu transport …

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Snorkel‐tag based affinity chromatography for recombinant extracellular vesicle purification

Madhusudhan Reddy Bobbili, André Görgens, Yan Yan, Stefan Vogt et autres

Extracellular vesicles (EVs) are lipid nanoparticles and play an important role in cell-cell communications, making them potential therapeutic agents and allowing to engineer for targeted drug delivery. The expanding applications of EVs in next generation medicine is still limited by existing tools …

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Snorkel-tag Based Affinity Chromatography for Recombinant Extracellular Vesicle Purification

Madhusudhan Reddy Bobbili, Andre Gorgen, Yan Yan, Stefan Vogt et autres

Abstract Extracellular vesicles (EVs) are lipid nanoparticles and play an important role in cell-cell communications, making them potential therapeutic agents and allowing to engineer for targeted drug delivery. The expanding applications of EVs in next generation medicine are still limited by existing …

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Cadmium alters whole animal ionome and promotes the re-distribution of iron in intestinal cells of Caenorhabditis elegans

Anuj Kumar Sharma, Lydia Finney, Stefan Vogt, Olena K. Vatamaniuk

The chronic exposure of humans to the toxic metal cadmium (Cd), either occupational or from food and air, causes various diseases, including neurodegenerative conditions, dysfunction of vital organs, and cancer. While the toxicology of Cd and its effect on the homeostasis of …

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Epitaxial growth of (FeCo)x Ge1-x (001)

Yong S. Chu, L. He, Brian A. Collins, F. Tsui et autres

The epitaxial growth of (FeCo)x Ge1-x films on Ge and GaAs (001) substrates has been studied systematically with x in the range between 0 and 17 at. %, using combinatorial molecular beam epitaxy (MBE) techniques. Complementary doping using the two transition metal …

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Evidence for strain compensation in stabilizing epitaxial growth of highly doped germanium

Stefan Vogt, F. Tsui, L. He, Yong S. Chu et autres

We report on a study of the epitaxial phase diagram of Co- and Mn-doped Ge(001) magnetic semiconductors. Complementary doping using dopants from different groups of elements can compensate for the effects of lattice strain caused by the doping species. Reducing lattice mismatch …

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Accelerated deep self-supervised ptycho-laminography for three-dimensional nanoscale imaging of integrated circuits

Iksung Kang, Yi Jiang, Mirko Holler, Manuel Guizar‐Sicairos et autres

Three-dimensional inspection of nanostructures such as integrated circuits is important for security and reliability assurance. Two scanning operations are required: ptychographic to recover the complex transmissivity of the specimen, and rotation of the specimen to acquire multiple projections covering the 3D spatial …

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