Zuodong Zhao

Influence of sex and age on the gene expression of periodontal and pulp tissues during orthodontic tooth movement

Zuodong Zhao, Steffen Fieuws, Catia Attanasio, Mariano Simón Pedano et autres

Orthodontic tooth movement (OTM) is a complex biological process triggered by orthodontic forces (OF). This study aims to study the influence of sex and age on the gene expression of the dental pulp (DP) and periodontal ligament (PDL) of human premolars subjected …

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GLM-4.5: Agentic, Reasoning, and Coding (ARC) Foundation Models

Team, Aohan Zeng, Xin Lü, Qinkai Zheng et autres

We present GLM-4.5, an open-source Mixture-of-Experts (MoE) large language model with 355B total parameters and 32B activated parameters, featuring a hybrid reasoning method that supports both thinking and direct response modes. Through multi-stage training on 23T tokens and comprehensive post-training with expert …

Biomechanical and histomorphometric evaluation of biodegradable mini-implants for orthodontic anchorage in the mandible of beagle dogs

Shuo Wang, Zuodong Zhao, Chang Liu

OBJECTIVE: To evaluate the effectiveness of a mini-implant composed of unsintered hydroxyapatite, poly (L-lactic acid) and poly(lactic-co-glycolic acid) (u-HA/PLLA/PLGA) composites as an anchorage device under consistent orthodontic force (OF) loading in vivo. METHODS: An mandible model in beagle dogs was introduced. 144 …

cn, be (code pays fourni par la source)

Defective Incisor Development in Smad Interacting Protein 1 (Sip1) Null Mice

Marie De Laet, Julie Bertrand, Elisa Vingerhoedt, Zuodong Zhao et autres

OBJECTIVES: The aim of this study is to histologically and morphologically describe the dental and craniofacial manifestations of a novel mouse model involving a conditional mutation in the Smad Interacting Protein 1 (Sip1) gene. MATERIALS AND METHODS: Since targeted inactivation of Sip1 …

be, pl (code pays fourni par la source)

Genetic Mutations Leading to Dento‐Maxillofacial Abnormalities in Mice: A Systematic Review

Zuodong Zhao, Achiel Van Bruwaene, Eva Lievens, Marie De Laet et autres

INTRODUCTION: To systematically review the available literature reporting on genetic mutations leading to dento-maxillofacial malformations in mice. MATERIALS AND METHODS: An electronic search was performed across Embase, PubMed, Web of Science, and Scopus databases up to May 2024, targeting all in vivo …

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Author response for "Genetic Mutations Leading to Dento‐Maxillofacial Abnormalities in Mice: A Systematic Review"

Zuodong Zhao, Achiel Van Bruwaene, Marie De Laet, Catia Attanasio et autres

Periodontal Ligament Reactions to Orthodontic Force: A Transcriptomic Study on Maxillary and Mandibular Human Premolars

Zuodong Zhao, Mihai Tarce, Maria Georgopoulou, Chen Zong et autres

AIMS: Orthodontic force (OF) induces a variety of reactions in the periodontal ligament (PDL) that could potentially account for individual variability regarding orthodontic tooth movement (OTM). This study investigates the transcriptomic profile of human PDL tissue subjected to OF in vivo for …

be, hk (code pays fourni par la source)

How does orthodontic tooth movement influence the dental pulp? RNA‐sequencing on human premolars

Zuodong Zhao, Catia Attanasio, Chen Zong, Mariano Simón Pedano et autres

OBJECTIVES: The objective of this study is to analyse the gene expression profile of the dental pulp (DP) of human premolars subjected to 7 and 28 days of orthodontic force (OF) in vivo by using RNA sequencing. The maxillary and mandibular DP …

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Comparison of human dental tissue RNA extraction methods for RNA sequencing

Zuodong Zhao, Catia Attanasio, Mariano Simón Pedano, María Cadenas de Llano‐Pérula

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Composite System of 3D-Printed Polymer and Acellular Matrix Hydrogel to Repair Temporomandibular Joint Disc

Ping Hua Yi, Jiadi Liang, Futing Huang, Zuodong Zhao et autres

Tissue engineering is a promising approach to restore or replace a damaged temporomandibular joint (TMJ) disc. However, constructing a scaffold that can mimic biomechanical and biological properties of the natural TMJ disc remains a challenge. In this study, three-dimensional (3D) printing technology …

cn (code pays fourni par la source)

Quantitative evaluation of retromolar space in adults with different vertical facial types:

Zuodong Zhao, Qiuyu Wang, Ping Cheng Yi, Futing Huang et autres

OBJECTIVE: To investigate the differences in mandibular retromolar space among skeletal Class I subjects with different vertical divergence using cone-beam computed tomography (CBCT). MATERIALS AND METHODS: A total of 123 skeletal Class I patients (aged 20-40 years) were categorized into hypodivergent, normodivergent, …

Acellular matrix hydrogel for repair of the temporomandibular joint disc

Jiadi Liang, Ping Hua Yi, Xiaojin Wang, Futing Huang et autres

Application of tissue-derived extracellular matrix (ECM) biomaterials in the repair of the temporomandibular joint (TMJ) disc is a promising approach for the treatment of disc abrasion and perforation, particularly for the young patient population. Although decellularized ECM (dECM) scaffolds preserve tissue-specific structures …

cn, us (code pays fourni par la source)