Nikolaos Vlachadis

A Review of Endometrial Cancer

Nikolaos Vlachadis, Nikolaos Machairiotis, Periklis Panagopoulos

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Mapping the General Fertility Rate in Greece: A Time-Trend Nationwide Analysis (1956-2024)

Chrysi Christodoulaki, Nikolaos Vlachadis, Charalampos Theofanakis, Rafaela Panagopoulou et autres

BACKGROUND: Accurate assessment of fertility rates and their long-term trends is essential for understanding reproductive dynamics, anticipating the healthcare and socioeconomic consequences of demographic change, and informing family planning and population policies. The aim of this study was to investigate long-term trends …

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Investigating the Demographic Foundation of Fertility: Temporal Trends in the Female Population of Reproductive Age in Greece, 1956–2024

Nikolaos Vlachadis, Chrysi Christodoulaki, Charalampos Theofanakis, Nikolaos Machairiotis et autres

OBJECTIVE: The objective of this study is to investigate long-term temporal trends in the size and age structure of the population of women of reproductive age (WRA) in Greece. MATERIALS AND METHODS: Data on the estimated mid-year WRA population (15-44 years) in …

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Trends in the Prevalence of Macrosomia Among Live Births in Greece: A Nationwide Analysis, 1980-2023

Nikolaos Vlachadis, Chrysi Christodoulaki, Rafaela Panagopoulou, Ioanna Petrakou et autres

OBJECTIVES: The present study aimed to estimate macrosomia rates in Greece and investigate their temporal trends during the period 1980-2023. METHODS: This nationwide population-based study analyzed official birth registry data obtained from the Hellenic Statistical Authority. The dataset included 4,593,229 live births …

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Temporal Trends in the Impact of Preterm Birth on Low Birthweight Rates in Greece

Nikolaos Vlachadis, Nikolaos Machairiotis, Dimos Sioutis, Konstantinos Louis et autres

BACKGROUND AND OBJECTIVES: In Greece, both the preterm birth rate (PBR) and the low birthweight rate (LBWR) have risen sharply in recent decades, reaching among the highest levels in high-income countries and posing a substantial public health concern. This study aimed to …

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Atypical Polypoid Adenomyoma in a Patient with Hyperprolactinemia: a Novel Case and Systematic Review of the Systematic Reviews

Panagiotis Peitsidis, Nikolaos Vlachadis, Stephane Zervoudis, Christos R Iavazzo et autres

Background: A 34-year-old nulligravid lady was referred to the outpatient gynecology department with the symptoms of abnormal menstrual bleeding and mild anemia. A transvaginal ultrasound (TVS) revealed the presence of a hyperechoic lesion measuring 9.5x4.5 mm in the uterine cavity at the …

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Combined Burden of Preterm and Low Birthweight Births in Greece: A Nationwide Time-Trend Analysis

Nikolaos Vlachadis, Dimos Sioutis, Nikolaos Machairiotis, Charalampos Theofanakis et autres

INTRODUCTION: The objective of this study was to assess the combined burden of preterm and low birthweight (LBW) births in Greece from 1980 to 2023, using this measure as a proxy for small vulnerable newborns (SVN), the neonatal population at heightened risk …

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Maternal Age Trends and Patterns in Greece (1956–2023): A Nationwide Analysis

Nikolaos Vlachadis, Dimos Sioutis, Nikolaos Machairiotis, Charalampos Theofanakis et autres

INTRODUCTION: Advanced maternal age is associated with an increased risk of major pregnancy complications. This study aims to investigate long-term trends in maternal age at childbirth in Greece, providing a comprehensive analysis of the evolving distribution of live births by maternal age …

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Time-Trend Analysis of Low Birthweight in Greece: Mapping a Heavy Public Health Burden

Nikolaos Vlachadis, Dimos Sioutis, Chryssi Christodoulaki, Nikolaos Machairiotis et autres

INTRODUCTION: Low birthweight is a critical determinant of neonatal and infant mortality and is further associated with several long-term adverse health outcomes. This study aims to comprehensively analyze low birthweight rate (LBWR) trends in Greece from 1980 to 2023. MATERIALS AND METHODS: …

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A Genetic Risk Score for Recurrent Miscarriages Based on Polymorphisms in Platelet Glycoproteins and Adhesion Molecules Genes

Nikolaos Vlachadis, Chrysi Christodoulaki, Vassilios Tsamadias, Panagiotis Peitsidis et autres

Background/Objectives: The objective of the study was to explore the combined effect of polymorphisms in the platelet glycoproteins Ia (GpIa) and IIIa (GpIIIa), along with the platelet-endothelial cell adhesion molecule-1 (PECAM-1) and P-Selectin genes, on the risk of recurrent pregnancy loss. Methods: …

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Time Trend Analysis of Early Term Births in Greece (1980-2023): Persistent High Rates Raise Public Health Concerns

Nikolaos Vlachadis, Chryssi Christodoulaki, Nikolaos Machairiotis, Dimos Sioutis et autres

INTRODUCTION: Neonates born at 37-38 weeks of gestation have been shown to face a relatively higher risk of mortality and various morbidities compared to those born at full term (39-41 weeks). The aim of this study was to conduct a comprehensive analysis …

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Trend Analysis of the Sex Ratio at Birth in Greece

Nikolaos Vlachadis, Chryssi Christodoulaki, Nikolaos Machairiotis, Konstantinos Louis et autres

INTRODUCTION: The sex ratio at birth, defined as the ratio of male to female live births, is a key indicator in the study of human reproduction and demographic patterns. This study aims to systematically examine the sex ratio in Greece and analyze …

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