Madhuri Vikas Shinde

Asymmetric Ring-Opening Reactions of Aza- and Oxa-bicyclic Alkenes with Boronic Acids Using a Palladium/Zinc Co-catalytic System

Wei Zhang, Jingchao Chen, Guang‐Zhi Zeng, Fan Yang et autres

The asymmetric ring opening reactions of bicyclic alkenes with boronic acids were accomplished by using a highly active palladium/zinc co-catalytic system that was suitable for both azabenzonorbornadienes and oxabenzonorbornadienes, which were transformed to the corresponding chiral hydronaphthalene products in high yields (up …

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Palladium/zinc co-catalyzed asymmetric transfer hydrogenation of oxabenzonorbornadienes with alcohols as hydrogen sources

Fujie Ma, Jingchao Chen, Fan Yang, Madhuri Vikas Shinde et autres

Asymmetric transfer hydrogenation of oxabenzonorbornadienes was realized by using alcohols as hydrogen sources under a co-catalytic system of palladium and zinc. Both primary and secondary alcohols could serve as reductants and afforded enantiomerically enriched 1,2-dihydronaphth-1-ol products with high optical purities.

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CCDC 1508992: Experimental Crystal Structure Determination

Fujie Ma, Jingchao Chen, Fan Yang, Madhuri Vikas Shinde et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

CCDC 1526719: Experimental Crystal Structure Determination

Fujie Ma, Jingchao Chen, Fan Yang, Madhuri Vikas Shinde et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

Palladium/Lewis Acid Co-catalyzed Divergent Asymmetric Ring-Opening Reactions of Azabenzonorbornadienes with Alcohols

Fan Yang, Jingchao Chen, Jianbin Xu, Fujie Ma et autres

By fine tuning the combinations of chiral palladium catalysts and Lewis acids, both the additional and reductive asymmetric ring-opening reactions of azabenzonorbornadienes with alcohols were accomplished with good chemoselectivity, regioselectivity, and enantioselectivity. It was proven that the reductive ring-opening products were generated …

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Identification of noreremophilane-based inhibitors of angiogenesis using zebrafish assays

Kalai Mangai Muthukumarasamy, Kishor L. Handore, Dipti N. Kakade, Madhuri Vikas Shinde et autres

Noreremophilanes are a rare class of cis-hydrindanes produced by genus Ligularia herbaceous plants which are known to exhibit interesting biological activities. We synthesized cis-hydrindanes based on a naturally occurring noreremophilane scaffold using a Diels-Alder/aldol sequence and screened them for multiple biological activities …

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Synthesis of novel N-cyclopentenyl-lactams using the Aubé reaction

Madhuri Vikas Shinde, Rohini S. Ople, Ekta Sangtani, Rajesh G. Gonnade et autres

A novel and convenient method utilizing the Aubé reaction to access a new class of compounds that are similar to carbocyclic nucleosides is reported. The azido alcohol derived from Vince lactam undergoes the Aubé reaction with various cyclic ketones to give cyclopentenyl-substituted …

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CCDC 1009597: Experimental Crystal Structure Determination

Kalai Mangai Muthukumarasamy, Kishor L. Handore, Dipti N. Kakade, Madhuri Vikas Shinde et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

CCDC 1014400: Experimental Crystal Structure Determination

Madhuri Vikas Shinde, Rohini S. Ople, Ekta Sangtani, Rajesh G. Gonnade et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

Enantiodivergent routes to (+) and (−)-novioses from (−)-pantolactone

B. M. Rajesh, Madhuri Vikas Shinde, Gujjary Srinivas, Javed Iqbal et autres

Noviose, a rare sugar moiety present in many biologically interesting molecules such as novobiocin and tiacumicin was obtained through formal synthesis in (+)- and (−)-forms starting from commercially available (−)-pantolactone in an enantiodivergent manner.

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