Feiyu Yang

Hydrogen‐Bond Network‐Directed Controllable Assembly of Stable Cyanine J‐Aggregates for Long‐Term and High‐Contrast In Vivo Imaging

Feiyu Yang, Yifeng Ou, Jun‐Liang Zhou, Ping‐Zhao Liang et autres

Optical probes based on near-infrared region (NIR) small-molecule dyes have emerged as an indispensable tool for contemporary in vivo biomedical research. Nevertheless, the majority of the reported NIR small-molecule probes are plagued by issues such as poor stability, short excitation wavelength, and …

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Hydrogen‐Bond Network‐Directed Controllable Assembly of Stable Cyanine J‐Aggregates for Long‐Term and High‐Contrast In Vivo Imaging

Feiyu Yang, Yifeng Ou, Jun‐Liang Zhou, Ping‐Zhao Liang et autres

ABSTRACT Optical probes based on near‐infrared region (NIR) small‐molecule dyes have emerged as an indispensable tool for contemporary in vivo biomedical research. Nevertheless, the majority of the reported NIR small‐molecule probes are plagued by issues such as poor stability, short excitation wavelength, …

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3D Spatiotemporal Electrophysiology of Cardiac Organoids Using Shell Microelectrode Arrays

Soo Jin Choi, Zhaoyu Liu, Feiyu Yang, Hanwen Wang et autres

Cardiac organoids have emerged as powerful platforms for modeling human heart development and disease. However, traditional 2D microelectrode arrays (MEAs) are limited to planar recordings and fail to capture the 3D propagation of electrical signals. Here, programmable, shape-adaptive, organoid-encapsulating shell MEAs are …

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3D Spatiotemporal Activation Mapping of Cardiac Organoids Using Conformal Shell Microelectrode Arrays (MEAs)

Deok‐Ho Kim, Soo Jin Choi, Zhaoyu Liu, Feiyu Yang et autres

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Graphene-integrated mesh electronics with converged multifunctionality for tracking multimodal excitation-contraction dynamics in cardiac microtissues

Hongyan Gao, Zhien Wang, Feiyu Yang, Xiaoyu Wang et autres

Cardiac microtissues provide a promising platform for disease modeling and developmental studies, which require the close monitoring of the multimodal excitation-contraction dynamics. However, no existing assessing tool can track these multimodal dynamics across the live tissue. We develop a tissue-like mesh bioelectronic …

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Imaging and detecting intercellular tensile forces in spheroids and embryoid bodies using lipid-modified DNA probes

Qian Tian, Feiyu Yang, Han Jiang, Priyanka Bhattacharyya et autres

Cells continuously experience and respond to different physical forces that are used to regulate their physiology and functions. Our ability to measure these mechanical cues is essential for understanding the bases of various mechanosensing and mechanotransduction processes. While multiple strategies have been …

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Directional Cell Migration Guided by a Strain Gradient

Feiyu Yang, Pengcheng Chen, Han Jiang, Tianfa Xie et autres

Strain gradients widely exist in development and physiological activities. The directional movement of cells is essential for proper cell localization, and directional cell migration in responses to gradients of chemicals, rigidity, density, and topography of extracellular matrices have been well-established. However; it …

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Synthesis, Antibacterial Activity, and Structure–Activity Relationship of Fusaric Acid Analogs

Qing‐Yan Zhang, Feiyu Yang, Shang‐Gao Liao, Bing Wang et autres

Forty‐one fusaric acid analogs possessing a pyridine carboxylic acid scaffold have been synthesized. The antibacterial activity results demonstrated that compounds 5b, 7b, 8c, and 8d displayed strong antibacterial activities against Staphylococcus aureus ATCC25923 with minimum inhibitory concentrations (MICs) of 4–16 μg/mL. Molecular …

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Two new dihydroisocoumarins with antimicrobial activities from the fungus Penicillium sp. XR046 collected from Xinren coal area

Guo‐Bo Xu, Feiyu Yang, Xinyu Wu, Rui Li et autres

Two new dihydroisocoumarins (1 and 2), together with six known compounds (3–8), were isolated from the fungus Penicillium sp. XR046 collected from the Xinren coal area of Guizhou province in China. Their structures were elucidated on the basis of spectroscopic analysis. The …

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A novel monopartite dsRNA virus isolated from the phytopathogenic fungus Ustilaginoidea virens strain GZ-2

Tingting Zhang, Xiangxing Zeng, Zhu Zeng, Zuquan Hu et autres

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