Sayantanee Mukherjee

Role of Exosomes in Epithelial–Mesenchymal Transition

Bikramjit Bhattacharya, Sagnik Nag, Sayantanee Mukherjee, Mrunal Kulkarni et autres

Epithelial-mesenchymal transition (EMT) is a fundamental process driving cancer metastasis, transforming non-motile cells into a motile population that migrates to distant organs and forms secondary tumors. In recent years, cancer research has revealed a strong connection between exosomes and the EMT. Exosomes, …

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Unlocking Exosome-Based Theragnostic Signatures: Deciphering Secrets of Ovarian Cancer Metastasis

Sayantanee Mukherjee, Sagnik Nag, Nobendu Mukerjee, Swastika Maitra et autres

Ovarian cancer (OC) is a common gynecological cancer worldwide. Unfortunately, the lack of early detection methods translates into a substantial cohort of women grappling with the pressing health crisis. The discovery of extracellular vesicles (EVs) (their major subpopulation exosomes, microvesicles, and apoptotic …

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Clinical Theranostics Trademark of Exosome in Glioblastoma Metastasis

Sagnik Nag, Bikramjit Bhattacharya, Swagata Dutta, Debashmita Mandal et autres

Glioblastoma (GBM) is an aggressive type of cancer that has led to the death of a large population. The traditional approach fails to develop a solution for GBM's suffering life. Extensive research into tumor microenvironments (TME) indicates that TME extracellular vesicles (EVs) …

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Exosome DNA: An untold story of cancer

Bikramjit Bhattacharya, Rajib Dhar, Sayantanee Mukherjee, Sukhamoy Gorai et autres

Abstract Exosome is nanosized tiny membrane‐bound vesicles and is a subpopulation of extracellular vesicles (EVs). In general, it participates in intercellular communication and acts as a messenger of several pathological complications. Exosome and cancer interlink is the most exciting domain of current …

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Exosomal miRNAs and breast cancer: a complex theranostics interlink with clinical significance

Sayantanee Mukherjee, Rajib Dhar, Swathi Jonnalagadda, Sukhamoy Gorai et autres

Breast cancer (BC) remains the most challenging global health crisis of the current decade, impacting a large population of females annually. In the field of cancer research, the discovery of extracellular vesicles (EVs), specifically exosomes (a subpopulation of EVs), has marked a …

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Exosome-Based Smart Drug Delivery Tool for Cancer Theranostics

Rishav Kar, Rajib Dhar, Sayantanee Mukherjee, Sagnik Nag et autres

Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles derived from the plasma membrane. The main activity of exosomes is cellular communication. In cancer, exosomes play an important rolefrom two distinct perspectives, one related to carcinogenesis and the other as theragnostic and drug …

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Cancer stem cells (CSCs): key player of radiotherapy resistance and its clinical significance

Saminur Hoque, Rajib Dhar, Rishav Kar, Sayantanee Mukherjee et autres

Cancer stem cells (CSCs) are self-renewing and slow-multiplying micro subpopulations in tumour microenvironments. CSCs contribute to cancer's resistance to radiation (including radiation) and other treatments. CSCs control the heterogeneity of the tumour. It alters the tumour's microenvironment cellular singling and promotes epithelial-to-mesenchymal …

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Interrelation between extracellular vesicles miRNAs with chronic lung diseases

Rajib Dhar, Sayantanee Mukherjee, Nobendu Mukerjee, Dattatreya Mukherjee et autres

Extracellular vehicles (EVs) are nanoscale lipid bilayer vesicles that carry biologically active biomolecule cargos like proteins, lipids, and nucleic acids (DNA, RNA) outside of the cell. Blood (serum/plasma), urine, and bronchoalveolar lavage fluid are all examples of biofluids from which they may …

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Neem Leaf Glycoprotein Facilitates Lung Carcinoma- Associated Antigen-Specific Anti-Cancer Immune Response Utilizing Macrophage-Mediated Antigen Presentation and Induction of Type 1 Cytokines Coupled with Nitric Oxide Production

Akanksha Rai, Akshaya Mahalakshmi Surendran, Krithika Nandakumar, Shreyosi Bose et autres

Effect of Knudsen Number, Lid Velocity and Velocity Ratio on Flow Features of Single and Double Lid Driven Cavities

Sayantanee Mukherjee, Vahid Shahabi, R Gowtham, K. S. Rajan et autres

Effects of Knudsen number, lid velocity and velocity ratio are investigated on the flow features of single lid driven cavity with an aspect ratio of one and double lid driven cavity of aspect ratio two. Knudsen numbers studied are 0.01(early slip regime), …

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