Douglas Curran‐Everett

Chronic Obstructive Pulmonary Disease Exacerbations Increase the Risk of Subsequent Cardiovascular Events: A Longitudinal Analysis of the COPDGene Study

Han‐Mo Yang, Min Hyung Ryu, Vincent J. Carey, Gregory L. Kinney et autres

BACKGROUND: Cardiovascular disease (CVD) is the most important comorbidity in patients with chronic obstructive pulmonary disease (COPD). COPD exacerbations not only contribute to COPD progression but may also elevate the risk of CVD. This study aimed to determine whether COPD exacerbations increase …

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Primer on reporting statistics: kayaks and walking trees once more

Douglas Curran‐Everett

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Prevalence of abnormal spirometry in individuals with a smoking history and no known obstructive lung disease

Thuonghien V. Tran, Gregory L. Kinney, Alejandro P. Comellas, Karin Ferneyhough Hoth et autres

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Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

Auyon Ghosh, Brian D. Hobbs, Jeong Hyun Yun, Aabida Saferali et autres

BACKGROUND: Chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) are characterized by shared exposures and clinical features, but distinct genetic and pathologic features exist. These features have not been well-studied using large-scale gene expression datasets. We hypothesized that there are …

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Factors Associated with Persistence of Severe Asthma from Late Adolescence to Early Adulthood

Neema Izadi, David Baraghoshi, Douglas Curran‐Everett, Robert S. Zeiger et autres

Abstract Rationale Asthma in children generally starts as being mild but may progress to being severe and may stay severe for unknown reasons. Objectives To identify factors in childhood that predict the persistence of severe asthma in late adolescence and early adulthood. …

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Emphysema Progression and Lung Function Decline Among Angiotensin Converting Enzyme Inhibitors and Angiotensin-Receptor Blockade Users in the COPDGene Cohort

Ashraf Fawzy, Nirupama Putcha, Peter J. Castaldi, Michael H. Cho et autres

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The Association Between Lung Hyperinflation and Coronary Artery Disease in Smokers

Divay Chandra, Aman Gupta, Gregory L. Kinney, Carl R. Fuhrman et autres

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MnTE‐2‐PyP disrupts Staphylococcus aureus biofilms in a novel fracture model

Sarah E. Lindsay, Hunter G. Lindsay, Julia G Kallet, Michael Raymond Weaver et autres

Biofilm-associated infections in orthopedic surgery lead to worse clinical outcomes and greater morbidity and mortality. The scope of the problem encompasses infected total joints, internally fixed fractures, and implanted devices. Diagnosis is difficult. Cultures are often negative, and antibiotic treatments are ineffective. …

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Stability of Do-Not-Resuscitate Orders in Hospitalized Adults: A Population-Based Cohort Study*

Anuj Mehta, Allan J. Walkey, Douglas Curran‐Everett, Daniel D. Matlock et autres

OBJECTIVES: Prior work has shown substantial between-hospital variation in do-not-resuscitate orders, but stability of do-not-resuscitate preferences between hospitalizations and the institutional influence on do-not-resuscitate reversals are unclear. We determined the extent of do-not-resuscitate reversals between hospitalizations and the association of the readmission …

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Anatomic evaluation of radiographic landmarks for accurate straight antegrade intramedullary nail placement in the humerus

Peter S. Johnston, Armodios M. Hatzidakis, Yahia M. Tagouri, Douglas Curran‐Everett et autres

BACKGROUND: Neurovascular insult, nonunion, and iatrogenic rotator cuff injury are concerns when using an intramedullary nail (IMN) for proximal humerus fracture. The purpose of this study was to identify a reproducible starting point and intraoperative imaging for nail insertion optimizing nail depth, …

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The atopic march and Staphylococcus aureus colonization are associated with fall birth

Jessica Hui, Elena Goleva, Douglas Curran‐Everett, Donald Y.M. Leung

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Evolution in statistics: P values, statistical significance, kayaks, and walking trees

Douglas Curran‐Everett

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