Tamara Gojković

Sex differences in cholesterol metabolism and their association with SCORE2 cardiovascular risk based on cholesterol homeostasis markers and principal component analysis

Sandra S. Vladimirov, Tamara Gojković, Nataša Bogavac‐Stanojević, Aleksandra Zeljković et autres

Abstract Background Sex‐related differences in cholesterol metabolism may influence cardiovascular disease risk and outcomes. Understanding these differences in the context of SCORE2 predicted cardiovascular risk could support the implementation of sex‐specific prevention and therapeutic protocols. Methods In this cross‐sectional study, serum levels …

rs (code pays fourni par la source)

Phospholipid transfer protein: The link between lipid metabolism and inflammation in healthy pregnancy and pregnancy with cardiometabolic complications

Marko Stanković, Jelena Munjas, Minja Derikonjic, Aleksandra Zeljković et autres

Background: Phospholipid transfer protein (PLTP) regulates high-density lipoprotein (HDL) remodelling by transferring cholesterol and phospholipids and affecting particle size and function. Pregnancy alters lipid metabolism, but the adaptation of PLTP to pregnancy remains poorly understood. This study investigated longitudinal changes in PLTP …

rs (code pays fourni par la source)

Metabolic Dysfunction-Associated Steatotic Liver Disease Is Characterized by Enhanced Endogenous Cholesterol Synthesis and Impaired Synthesis/Absorption Balance

Irena Frankovic, Aleksandra Zeljković, Ivana D. Djuricic, Ana Ninić et autres

Cholesterol accumulation plays a significant role in the pathogenesis of metabolic-dysfunction-associated steatotic liver disease (MASLD), yet changes in cholesterol homeostasis in MASLD remain insufficiently investigated. This study aimed to examine alterations in cholesterol synthesis and absorption by measuring plasma levels of endogenous …

rs (code pays fourni par la source)

Integrative prediction models of gestational diabetes mellitus: Insights from lipidomic profiling

Marija Sarić Matutinović, Milica Miljkovic Trailovic, Tamara Antonić, Sandra Vladimirov et autres

rs (code pays fourni par la source)

Analysis of non-cholesterol sterols and fatty acids in patients with graves’ orbitopathy: insights into lipid metabolism in relation to the clinical phenotype of disease

Marija Sarić Matutinović, Sandra Vladimirov, Tamara Gojković, Ivana D. Djuricic et autres

rs, cz, pl, de (code pays fourni par la source)

Associations of excessive gestational weight gain with changes in components of maternal reverse cholesterol transport and neonatal outcomes

Minja Derikonjic, Jelena Vekić, Aleksandra Stefanović, Marija Sarić Matutinović et autres

Excessive gestational weight gain may be associated with unfavorable pregnancy outcomes. We explored the impact of excessive weight gain on components of HDL metabolism in maternal plasma: sterol composition of HDL particles, distribution of HDL subclasses and SCARB1 , ABCA1 and ABCG1 …

rs (code pays fourni par la source)

Unraveling sphingolipid dynamics in late-onset preeclampsia: insights from lipidomic analysis

Aleksandra Stefanović, Aleksandra Zeljković, Tamara Gojković, Tamara Antonić et autres

Introduction: Sphingolipids, essential to trophoblast and endothelial function, may impact inflammation in preeclampsia. However, their specific role in late-onset preeclampsia remains unclear. To address this research gap, we analyzed sphingolipid profiles in pregnancies at high risk for preeclampsia development to identify potential …

rs (code pays fourni par la source)

Monocyte/HDL-cholesterol ratio as an early prognostic marker of pregnancy complications development

Jovana Vulić, Jelena Radojković, Jelena Vekić, Aleksandra Stefanović et autres

Pregnancy complications increase the long-term cardiovascular risk for both the mother and the child. Inflammation is a common mechanism underlying the development of pregnancy complications and atherosclerosis. This study aims to investigate whether the monocyte/HDL cholesterol ratio can serve as a predictive …

rs (code pays fourni par la source)

Association between systemic inflammation and lipid metabolism in the development of preeclampsia

Tamara Gojković, Daniela Ardalić, Gorica Banjac, Jelena Vekić et autres

Preeclampsia (PE) is a pregnancy complication marked by hypertension (≥ 140/90 mmHg) and proteinuria (≥ 300 mg/24 h), with an unclear pathogenesis involving inflammation and dyslipidemia. This study aimed to longitudinally examine changes in lipid status parameters and inflammatory markers in pregnant …

rs (code pays fourni par la source)

Abstract 70: Cellular senescence as a driver of preeclampsia

Sonja R. Suvakov, Tamara Gojković, Jennet Hatamova, Vladimir Dokic et autres

Background: Preeclampsia (PE) is a severe hypertensive disorder of pregnancy of unknown pathophysiology. We previously have reported the presence of senescence in kidney and fat tissue of PE women, as well as accelerated epigenetic aging, which prompted us to postulate that cellular …

us (code pays fourni par la source)

Abstract MP28: Advanced Lipid Status Parameters in Women With Preeclampsia

Tamara Gojković, Daniela Ardalić, Tamara Antonić, Gorica Banjac et autres

Preeclampsia (PE) is a hypertensive disorder associated with pregnancy, usually occurring after the 20th week of gestation, followed by proteinuria or signs of end-organ dysfunction. Early-onset preeclampsia is associated with placental dysfunction, while late-onset preeclampsia is recognized as a maternal disorder, influenced …

rs (code pays fourni par la source)

The association of the cholesterol metabolic profile and fatty acid content with the clinical phenotype of graves' orbitopathy

Matutinovic Marija Saric, Sopic Sandra Vladimirov, Miloš Žarković, Jasmina Ćirić et autres