Noncanonical-NF-κB activation and DDX3 inhibition reduces the HIV-1 reservoir by elimination of latently infected cells ex-vivo
Jade Jansen, Stefanie Kroeze, S. F. Paul Man, Matteo Andreini et autres
10 citationsMicrobiology Spectrum
Matteo Andreini
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15Publications signalées
411Citations signalées
0Affiliations récentes
Domaines associés
RNA Research and SplicingSynthesis and Biological EvaluationComputational Drug Discovery MethodsWnt/β-catenin signaling in development and cancerCancer-related gene regulation
Publications récentes
The FHP01 DDX3X Helicase Inhibitor Exerts Potent Anti-Tumor Activity In Vivo in Breast Cancer Pre-Clinical Models
Lisa Gherardini, Giovanni Inzalaco, Francesco Imperatore, Romina D’Aurizio et autres
5 citationsCancers
Optimization of linear and cyclic peptide inhibitors of KEAP1-NRF2 protein-protein interaction
Stefania Colarusso, Daniele De Simone, Tommaso Frattarelli, Matteo Andreini et autres
27 citationsBioorganic & Medicinal Chemistry
Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction
Jesus M. Ontoria, Ilaria Biancofiore, Paola Fezzardi, Federica Ferrigno et autres
29 citationsACS Medicinal Chemistry Letters
Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening
Lorenzo Turcano, Esther Torrente, Antonino Missineo, Matteo Andreini et autres
68 citationsPLoS neglected tropical diseases
Peptidomimetic nitrile inhibitors of malarial protease falcipain-2 with high selectivity against human cathepsins
Emanuela Nizi, Alessio Sferrazza, Danilo Fabbrini, Valentina Nardi et autres
26 citationsBioorganic & Medicinal Chemistry Letters
Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production
Alessandra Guidi, Cristiana Lalli, Roberto Gimmelli, Emanuela Nizi et autres
34 citationsPLoS neglected tropical diseases
Identification by High-Throughput Screening of Pseudomonas Acyl–Coenzyme A Synthetase Inhibitors
Lorenzo Turcano, Daniela Visaggio, Emanuela Frangipani, Antonino Missineo et autres
2 citationsSLAS DISCOVERY
The soluble Y115E–Y117E variant of human glutaminyl cyclase is a valid target for X-ray and NMR screening of inhibitors against Alzheimer disease
F. Di Pisa, Cecilia Pozzi, Manuela Benvenuti, Matteo Andreini et autres
10 citationsActa Crystallographica Section F Structural Biology Communications
siRNA screen identifies QPCT as a druggable target for Huntington's disease
María Jiménez-Sánchez, Wun Lam, Michael Hannus, Birte Sönnichsen et autres
99 citationsNature Chemical Biology
Structure–activity relationship and properties optimization of a series of Quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway
Arianna Nencini, Carmela Pratelli, Joanna Quinn, Massimiliano Salerno et autres
19 citationsEuropean Journal of Medicinal Chemistry
BACE1 inhibitors: A head group scan on a series of amides
Thomas J. Woltering, Wolfgang Wostl, Hans Hilpert, Mark Rogers‐Evans et autres
52 citationsBioorganic & Medicinal Chemistry Letters
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