Accès ouvert
2023
article
OpenAlex
Brett Baggett, Kevin R. Murphy, Elif Sengun, Eric Mi et autres
Progressive tissue remodeling after myocardial infarction (MI) promotes cardiac arrhythmias. This process is well studied in young animals, but little is known about pro-arrhythmic changes in aged animals. Senescent cells accumulate with age and accelerate age-associated diseases. Senescent cells interfere with cardiac …
us, tr, gb
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Jihong Li, Eric Mi, Arhat Pradhan, Bruce A. McClane
Clostridium perfringens type F food poisoning (FP) strains produce C. perfringens enterotoxin (CPE) to cause a common bacterial food-borne illness in the United States. During FP, CPE is synthesized in the intestines when C. perfringens sporulates. Besides CPE, FP strains also produce …
us
(code pays fourni par la source)
Accès ouvert
2021
preprint
OpenAlex
Brett Baggett, Kevin R. Murphy, Elif Sengun, Eric Mi et autres
Abstract Progressive tissue remodeling after myocardial infarction (MI) promotes cardiac arrhythmias. This process is well studied in young animals, but little is known about pro-arrhythmic changes in aged animals. Senescent cells accumulate with age and accelerate age-associated diseases. Senescent cells interfere with …
us, gb
(code pays fourni par la source)
Accès ouvert
2019
article
OpenAlex
John C. Freedman, Jihong Li, Eric Mi, Bruce A. McClane
Clostridium perfringens type F enteric diseases, which include a very common form of food poisoning and many cases of antibiotic-associated diarrhea, develop when type F strains sporulate and produce C. perfringens enterotoxin (CPE) in the intestines. Spores are also important for transmission …
us
(code pays fourni par la source)
Accès ouvert
2018
article
OpenAlex
Edwin K. Jackson, Eric Mi, Vladimir B. Ritov, Delbert G. Gillespie
SDF-1α (stromal cell–derived factor-1α) is a CXCR4-receptor agonist and DPP4 (dipeptidyl peptidase 4) substrate. SDF-1α, particularly when combined with sitagliptin to block the metabolism of SDF-1α by DPP4, stimulates proliferation of cardiac fibroblasts via the CXCR4 receptor; this effect is greater in …
us
(code pays fourni par la source)
Accès ouvert
2018
article
OpenAlex
Eric Mi, Jihong Li, Bruce A. McClane
Clostridium perfringens type F strains, which produce C. perfringens enterotoxin (CPE), are a major cause of gastrointestinal infections, including the second most prevalent bacterial foodborne illness and 5 to 10% cases of antibiotic-associated diarrhea. Virulence of type F strains is primarily ascribable …
us
(code pays fourni par la source)
2015
conference-abstract
OpenAlex
Edwin K. Jackson, Eric Mi, Vladimir B. Ritov, Delbert G. Gillespie
CXCR4 receptors mediate in part hypertension-induced cardiac fibrosis. This suggests that endogenous CXCR4-receptor agonists stimulate cardiac fibroblast (CF) proliferation; however, this possibility is unexplored. Although CXCL12 (aka SDF-1α) is the best described endogenous CXCR4 agonist, ubiquitin 1-76 (U-76) exists in the extracellular …
us, ru
(code pays fourni par la source)