Gábor Polony

[Vestibulocochlear infarct: a challenging diagnosis].

András Szilágyi, Anita Gáborján, Beáta Bencsik, László Tamás et autres

Vestibulocochlear infarct, most commonly associated with infarction of a terminal branch of the anterior inferior cerebellar artery, presents with acute vertigo and sensorineural hearing loss. It often mimics peripheral vestibular disorders and may show no abnormal findings on neuroimaging, making the diagnosis …

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Post-Radiation PET Shows Higher Diagnostic Accuracy in HPV-Negative Head and Neck Cancers

Kornél Dános, Angéla Horváth, Emese Kristóf, Imre Uri et autres

Background: Post-treatment evaluation of residual neck disease in head and neck squamous cell carcinoma (HNSCC) is challenging because of treatment-related changes and biological differences between HPV-positive and HPV-negative tumors. Methods: We performed a prospective single-center study of 58 node-positive HNSCC patients treated …

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The correlation between FDG-PET metabolic parameters, PD-L1 expression and p16/HPV status in oropharyngeal cancers

Angéla Horváth, Imre Uri, Emese Kristóf, Gábor Lotz et autres

PURPOSE: Immunotherapy targeting the PD-1/PD-L1 axis has emerged as a promising strategy in oropharyngeal squamous cell carcinoma (OPSCC). However, reliable non-invasive biomarkers to predict immune checkpoint expression and treatment response are still lacking. This study aimed to investigate the relationship between PET/CT-derived …

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Vestibulocochlearis infarktus: egy nehezen diagnosztizálható entitás = Vestibulocochlear infarct: a challenging diagnosis

András Szilágyi, Anita Gáborján, Beáta Bencsik, László Tamás et autres

A belső fület érintő infarktus, amely elsősorban az arteria cerebellaris anterior inferior egy végágának elzáródásával függ össze, heveny szédüléssel és sensorineuralis hallásvesztéssel jelentkezik. Gyakran a perifériás egyensúlyozó rendszert érintő kórképeket utánoz, a hagyományos képalkotó vizsgálatokon sem mutat kóros eltérést, megnehezítve ezzel a …

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Protective Effect of Selegiline (R-deprenyl) in Aminoglycoside-Induced Hearing Loss

Viktória Humli, Judit Szepesy, G. Zsilla, Ildikó Miklya et autres

Aminoglycoside antibiotics remain indispensable despite their ototoxicity. Like other sensorineural forms, aminoglycoside-induced hearing loss (AGIHL) has no effective pharmacotherapy. Oxidative stress, apoptosis, excitotoxicity and inflammation are key pathological factors of the disease. We hypothesised that selegiline, an irreversible monoamine oxidase-B (MAO-B) inhibitor …

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Evidence for the Necessity of Objective Hearing Tests in Cochlear Implantation Assessment: Excluding Functional Hearing Loss Cases

Anita Gáborján, Márton Kondé, Marianna Küstel, Nóra Kecskeméti et autres

Background/Objectives: Cochlear implantation is a crucial intervention for individuals with severe hearing loss, aiming to restore auditory function and improve quality of life. The decision to recommend cochlear implantation critically depends on accurate audiological evaluations. However, challenges arise when subjective assessments of …

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Characterization of middle ear microbiome in otitis media with effusion in Hungarian children: Alloiococcus otitidis may potentially hamper the microbial diversity

S Fekete, János Juhász, Nóra Makra, Zsuzsanna A. Dunai et autres

Abstract Introduction Although otitis media with effusion (OME) is a common cause of hearing impairment in children, little is known about its microbiological background. We aimed to analyse the microbiome of the middle ear fluid (MEF) in OME to identify microbiological, demographic …

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Prognostic nutritional index (PNI) correlates with survival in head and neck cancer patients more precisely than other nutritional markers – real world data

Imre Uri, Angéla Horváth, László Tamás, Gábor Polony et autres

PURPOSE: The survival benefit with higher body mass index (BMI) of patients suffering from head and neck squamous cell carcinoma (HNSCC) is documented as BMI paradox. As the early re-nourishment of high-risk patients determine survival, we searched for a nutritional status marker …

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Audiological outcomes after revision stapes surgeries: a systematic review

László Székely, Imre Uri, Ágnes Luka, Anita Gáborján et autres

PURPOSE: Revision stapes surgery is a challenging procedure performed in relatively small numbers compared to other middle ear procedures. Despite numerous data on hearing results of different middle ear surgeries, the audiological standards for successful outcome of this procedure are still not …

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Middle Ear Microbiome in Otitis Media with Effusion, the Role of Alloiococcus Otitidis

Dóra Szabó, S Fekete, János Juhász, Nóra Makra et autres

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Patient delay and its clinical significance among head and neck cancer patients in Hungary

Kornél Dános, Angéla Horváth, Judit Halász, László Tamás et autres

Introduction: Head and neck cancers represent a major health problem in Hungary. With their high incidence and mortality rates, Hungary is one of the world leaders in these indicators. The length of patient delay, defined as time from onset of symptoms to …

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Primary ossiculoplasties provide better hearing results than revisions: a retrospective cohort study

Judit Kálmán, Tamás Horváth, Kornél Dános, László Tamás et autres

PURPOSE: To evaluate the efficacy of ossicular chain reconstruction (OCR) in primary and revision surgeries, and to investigate the impact of the number of previous surgeries on hearing outcomes. METHODS: Retrospective analysis of cases with OCR due to chronic otitis in a …

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