Pat Swanson

The Where and the How:

Charmaine Wright, Verna Hensley, Neal Emery, Pat Swanson

A.S. is a 33-year-old autistic man who rents the apartment above his parents' garage.He is competitively employed at a 20 hour/week job where he is entitled, through Medicaid, to have the support of a Direct Support Professional (DSP), who serves as his …

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Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

Benjamin J. Raphael, Ralph H. Hruban, Andrew J. Aguirre, Richard A. Moffitt et autres

We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low neoplastic cellularity. Deep whole-exome sequencing revealed recurrent somatic mutations in KRAS, TP53, CDKN2A, SMAD4, RNF43, ARID1A, TGFβR2, GNAS, RREB1, and PBRM1. KRAS …

Abstract P5-12-04: Directed exercise intervention in breast cancer patients with arthralgias receiving aromatase inhibitors: A randomized pilot study

Ramya Varadarajan, Erin E. Helm, Cathy Arnold, Lori Huelsenbeck-Dill et autres

Abstract Purpose: Early discontinuation or non-adherence of AI therapy occurs in 25-50 % of patients due to treatment associated toxicities, including musculoskeletal symptoms such as arthralgias and myalgias. The goal of this pilot study is to evaluate the effect of a directed …

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Comprehensive molecular characterization of urothelial bladder carcinoma

John N. Weinstein, Rehan Akbani, Bradley M. Broom, Wenyi Wang et autres

Urothelial carcinoma of the bladder is a common malignancy that causes approximately 150,000 deaths per year worldwide. So far, no molecularly targeted agents have been approved for treatment of the disease. As part of The Cancer Genome Atlas project, we report here …

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Developing a hot-water drill system for the WISSARD project: 3. Instrumentation and control systems

Justin Burnett, Frank R. Rack, Daren Blythe, Pat Swanson et autres

Abstract The WISSARD (Whillans Ice Stream Subglacial Access Research Drilling) traversable hot-water drill system was designed to create various-diameter ice boreholes to a depth of >800 m, with most major components being controllable from a single user interface. The drill control system …

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