Ippei Chiba

Clinical development of molecular residual disease (MRD) and multi-cancer early detection (MCED) using liquid biopsy multiomics with artificial intelligence (AI)

Taro Shibuki, R. Yamashita, Tadayoshi Hashimoto, Takao Fujisawa et autres

BACKGROUND: Early detection of cancer and precise recurrence monitoring remain major unmet needs in oncology. Conventional screening is limited to a few cancer types, leaving nearly half of cancers without established programs. Multi-cancer early detection (MCED) tests based on circulating tumor biomarkers …

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Association of subjective and objective physical activity with home hypertension

Saki Hayashi, Mana Kogure, Ippei Chiba, Rieko Hatanaka et autres

Prevention of hypertension (HT), a risk factor for cardiovascular diseases, and blood pressure (BP) control are important. For the prevention and management of high BP, increased physical activity (PA) is recommended as a lifestyle intervention. Although various PA assessment methods exist, their …

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Correction: Association of olfactory and cognitive function test scores with hippocampal and amygdalar grey matter volume: a cross-sectional study

Shuichi Sato, Takao Imaeda, Shunji Mugikura, Naoko Mori et autres

The original version of this Article contained an error in the Methods section, under the subheading ‘Study procedures and data collection’, where the pleasant odour “cyclotene” was incorrectly stated as “cyclohexanone”.

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Genome-wide association study of social isolation in 63,497 Japanese individuals from the general population

Hisashi Ohseto, Kosuke Inoue, Ippei Takahashi, Taku Obara et autres

Social isolation, characterized by a lack of social connections with family, friends, and others, is associated with adverse health outcomes. However, the genetic contribution to the susceptibility to social isolation remains unclear. This study aimed to identify genetic loci associated with social …

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Genome-wide Association Study of Subcortical Brain Structures in Japanese Ancestry: The Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study

Genki Shinoda, Hisashi Ohseto, Taku Obara, Masatsugu Orui et autres

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Study Protocol and Characteristics of the Wearable Device Survey for Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study

Ippei Chiba, Naoki Nakaya, Shunji Mugikura, Mana Kogure et autres

Sleep and physical activity play a crucial role in brain and mental health. While traditional self-reported methods and research-grade accelerometers have several limitations, consumer-grade wearable devices, such as Fitbit, allow continuous, objective, and real-life data collection. The purpose of this article is …

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Sex difference in genetic risk in the prevalence of atrial fibrillation

Sayuri Tokioka, Masato Takase, Naoki Nakaya, Rieko Hatanaka et autres

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A case of restenosis of the proximal left anterior descending artery after aigioplasty using a cutting balloon

Kenji Ueshima, Ippei Chiba, Tomoya Akatsu

[A case of primary thymic carcinoid (author's transl)].

Z Taguchi, Takemi Hasegawa, F Tomita, T Ishidate et autres

Hepatic circulation by hepatic venous catheterization in patients with liver diseases (further studies) : Hepatic blood flow according to bromsulfalein (BSP) and indocyanine green (ICG) simultaneous constant infusion technic

Keiji Takahashi, I. Kaito, Shunichi Sato, Hisashi Sahara et autres

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[Autopsy case of leukemic reticulosarcoma].

Ryoichi Satodate, Ippei Chiba, S Ueda, Kyoko Katakura

Studies on the bile acid components in bile in diseases of the liver and biliary tract

I. Kaito, Shunichi Sato, Noriya Kikawada, Ippei Chiba

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