José Alhama

Additional data: Multi-kingdom microbial communities in pseudomyxoma peritonei mucin

Rafaela Pezzopane, Marina Barbudo-Lunar, Florina Iulia Bura, Melissa Granados-Rodríguez et autres

This deposit provides additional data for the research article "Multi-kingdom microbial communities in pseudomyxoma peritonei mucin" to ensure full transparency and reproducibility. The dataset comprises raw 16S and 18SrRNA sequencing data from Pseudomyxoma peritonei mucin samples, the R scripts utilized for statistical …

Additional data: Multi-kingdom microbial communities in pseudomyxoma peritonei mucin

Rafaela Pezzopane, Marina Barbudo-Lunar, Florina Iulia Bura, Melissa Granados-Rodríguez et autres

This deposit provides additional data for the research article "Multi-kingdom microbial communities in pseudomyxoma peritonei mucin" to ensure full transparency and reproducibility. The dataset comprises raw 16S and 18SrRNA sequencing data from Pseudomyxoma peritonei mucin samples, the R scripts utilized for statistical …

Storage of Alperujo influences composting performance: Insights into gaseous emissions and functional metagenomics

Francisco Javier Ruiz-Castilla, Marina Barbudo-Lunar, M.C. Gutiérrez, Carmen Michán et autres

Alperujo (AL), the primary by-product of olive oil extraction, poses a significant environmental challenge in the Mediterranean region. Understanding the AL composting process is essential for controlled aerobic revalorisation to obtain a stable and good quality organic amendment with the minimum environmental …

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Storage of Alperujo Influences Composting Performance: Insights into Gaseous Emissions and Functional Metagenomics

Francisco Javier Ruiz Castilla, Marina Barbudo Lunar, M.C. Gutiérrez, Carmen Michán et autres

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Accumulation, biochemical responses and changes in the redox proteome promoted by Ag and Cd in the burrowing bivalve Scrobicularia plana

Ana María Herruzo-Ruiz, Chiara Trombini, Marta Sendra, Carmen Michán et autres

, for 7 days in a controlled microcosm system. The levels of the metals were measured in the seawater, sediments and clam tissues. The possible toxic biological effects of Ag and Cd were studied using a battery of biochemical biomarkers that are …

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Biomethanisation of sewage sludge: Sonication pretreatment and monitoring of microbial communities

M.A. Martı́n, Antonio Serrano, Bárbara Rincón, M.C. Gutiérrez et autres

The improvement of mesophilic biomethanisation of recalcitrant sewage sludge derived from urban wastewater treatment through the application of a sonication pretreatment was evaluated in parallel in two pilot-scale anaerobic digesters (two biological replicates: reactors RA and RB). The valorisation process was monitored …

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Ions and nanoparticles of Ag and/or Cd metals in a model aquatic microcosm: Effects on the abundance, diversity and functionality of the sediment bacteriome

Ana María Herruzo-Ruiz, Chiara Trombini, Ignacio Moreno-Garrido, Julián Blasco et autres

Metals can be adsorbed on particulate matter, settle in sediments and cause alterations in aquatic environments. This study assesses the effect of Ag and/or Cd, both in ionic and nanoparticle (NP) forms, on the microbiome of sediments. For that purpose, aquatic controlled-microcosm …

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Breaking the Mucin Barrier: A New Affinity Chromatography-Mass Spectrometry Approach to Unveil Potential Cell Markers and Pathways Altered in Pseudomyxoma Peritonei

Antonio Romero‐Ruíz, Melissa Granados-Rodríguez, Florina I. Bura, Francisca Valenzuela-Molina et autres

BACKGROUND: Pseudomyxoma peritonei (PMP) is a rare peritoneal mucinous carcinomatosis with largely unknown underlying molecular mechanisms. Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy is the only therapeutic option; however, despite its use, recurrence with a fatal outcome is common. The lack of …

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Breaking the mucin barrier: a new affinity chromatography-mass spectrometry approach to unveil potential cell markers and pathways altered in Pseudomyxoma peritonei

Antonio Romero‐Ruíz, Melissa Granados-Rodríguez, Florina I. Bura, Francisca Valenzuela-Molina et autres

Abstract Background Pseudomyxoma peritonei (PMP) is a rare peritoneal mucinous carcinomatosis with unknown underlying molecular mechanisms. Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy is the only therapeutic option; however, despite its use, recurrence with a fatal outcome is common. The lack of …

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Mass spectrometry imaging in environmental monitoring: From a scarce existing past to a promising future

Ana María Herruzo-Ruiz, Ángela Peralbo‐Molina, Carmen Michán, José Alhama et autres

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Assessment of nitrification process in a sequencing batch reactor: Modelling and genomic approach

M.C. Gutiérrez, Alex Ernesto Muñoz Cáceres, Ana María Herruzo-Ruiz, José Ángel Siles et autres

Nitrification of ammoniacal nitrogen (N–NH4+) to nitrate (N–NO3-) was investigated in a lab-scale sequencing batch reactor (SBR) to evaluate its efficiency. During the nitrification process the removal of N–NH4+ reached 96%, resulting in 73% formation of N–NO3-. A lineal correlation (r2 = …

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Antitumor effect of a small-molecule inhibitor of KRASG12D in xenograft models of mucinous appendicular neoplasms

Mari Carmen Vazquez-Borrego, Melissa Granados-Rodríguez, Florina I. Bura, Ana Martínez-López et autres

Abstract Pseudomyxoma peritonei (PMP) is a rare disease characterized by a massive accumulation of mucus in the peritoneal cavity. The only effective treatment is aggressive surgery, aimed at removing all visible tumors. However, a high percentage of patients relapse, with subsequent progression …

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