Neda Parvini

Combined PD-1 and CTLA-4 Blockade Enhances NK Cell-Mediated Cytotoxicity Against Primary Lymphoblasts in Acute Lymphoblastic Leukemia

Neda Parvini, Amir Ali Hamidieh, Fardin Fathi, Abbas Ali Amini et autres

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CTLA-4 Blockade of Natural Killer Cells Increases Cytotoxicity against Acute Lymphoid Leukaemia Cells Neda.

Neda Parvini, Mohammad Esmaeil Akbari, Amir Ali Hamidieh, Fardin Fathi et autres

OBJECTIVE: There is interest in using cytotoxic T lymphocyte antigen-4 (CTLA-4) immunotherapy to treat blood cancers. Unfortunately, patients with acute lymphoblastic leukaemia (ALL) frequently exhibit resistance to treatment and natural killer (NK) cell exhaustion. This study aims to increase the cytotoxic potency …

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Hsp70, in Combination with IL-15 and PD-1 Blocker, Interferes with The Induction of Cytotoxic NK Cells in Relapsed Acute Myeloid Leukemia Patients.

Javad Firouzi, Abbas Hajifathali, Masoumeh Azimi, Neda Parvini et autres

OBJECTIVE: Natural killer (NK) cells are critical immune cells for acute myeloid leukemia (AML) targeting. However, little is known about the relationship between using checkpoint inhibitors and heat shock protein 70 (Hsp70) as NK cell activators to control AML. Therefore, the study …

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Design and finite element modeling of two–dimensional nanomechanical biosensors for SARS–CoV–2 detection

J. Payandehpeyman, Neda Parvini, K. Moradi, Nima Hashemian

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Detection of SARS-CoV-2 Using Antibody–Antigen Interactions with Graphene-Based Nanomechanical Resonator Sensors

J. Payandehpeyman, Neda Parvini, K. Moradi, Nima Hashemian

Coronavirus disease 2019 (COVID-19) is a newly emerging human infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Early diagnosis is essential to reducing the transmission rate and mortality of COVID-19. PCR-based tests are the gold standard for the confirmation …

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