Bernie Woulfe

Management of Staphylococcus aureus bacteraemia (SAB) in the oncology patient: Further evidence supports prompt removal of central venous catheters and shorter duration of intravenous antimicrobial therapy

Colum Dunne, Phelim Ryan, Roisín M. Connolly, Suzanne S. Dunne et autres

BACKGROUND: bacteraemia (SAB) is associated with relatively high risk of complications and high levels of mortality. Internationally, SAB management guidelines lack consensus and especially so regarding oncology patients. This is likely a reflection of insufficient randomised control trials (RCT) and the diversity …

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Long-term outcome data for patients with HER2- positive early-stage breast cancer treated with adjuvant trastuzumab: Benefit outside clinical trial setting

KI Quintyne, Bernie Woulfe, Coffey JC, Gupta Rk

Long-term outcome data for patients with HER2positive early-stage breast cancer treated with adjuvant trastuzumab: Benefit outside clinical trial setting

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Oncotype DX score, menopausal status and body mass index

Sarah Picardo, Jing Sui, Megan Greally, Bernie Woulfe et autres

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Cancer antigen 125 (CA125) and the law of unintended consequences.

Scheryll Alken, Linda Coate, Bernie Woulfe, Niamh O’Leary et autres

e18327 Background: CA125 is a serum tumour marker used to monitor patients with ovarian cancer (OvCa). Its usefulness as a screening tool remains unproven. There is no restriction in its use at our institution, a university teaching hospital. We sought to establish …

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Cost-effectiveness analysis (CEA) of adjuvant trastuzumab therapy use in HER2-positive early-stage breast cancer (EBC)

Keith Ian Quintyne, Bernie Woulfe, Anne Dee, Rajnish K. Gupta

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Lymph Node Ratio in Sentinel Lymph Node Biopsy Era: Are We Losing Prognostic Information?

Keith Ian Quintyne, Bernie Woulfe, John Calvin Coffey, Anne Merrigan et autres

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Lymph node ratio (LNR) in sentinel lymph node biopsy (SLNB) era: Are we losing prognostic information?

Keith Ian Quintyne, Bernie Woulfe, John Calvin Coffey, Rajnish K. Gupta

e12634 Background: The number of involved axillary lymph nodes (LNs) found on pathological assessment is regarded as a significant prognostic factor for patients with early-stage breast cancer (EBC). Recent reports have suggested that LNR may be a better surrogate at predicting cancer-specific …

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Male Breast Cancer: 9 Year Experience and Review in Mid-Western Ireland

Keith Ian Quintyne, Bernie Woulfe, Anne Merrigan, Rachel Keane et autres

Introduction: Male breast cancer (MBC) is a rare condition, which accounts for less than 1% of all breast cancer diagnoses.Because of this, there is a paucity of focussed work available and most data is derived from female breast cancer studies.Recently, there has …

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Pre-morbid anthropometric measurement and its impact on outcome in early-stage breast cancer in midwestern Ireland.

Keith Ian Quintyne, Bernie Woulfe, Rajnish K. Gupta

45 Background: Obesity has become a grave public health concern of global proportions, especially in many developed counties. Clinical obesity may be defined as a body mass indeed (BMI) of greater than or equal to 30kg/m2. Within recent times, growing interest has …

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Subcutaneous herceptin therapy

Niamh O’Donoghue, Keith Ian Quintyne, Bernie Woulfe, Rajnish K. Gupta et autres

In a recent issue of the Journal of Clinical Pharmacology, we noted with interest the paper by Wynne et al1 which compared subcutaneous and intravenous administration of trastuzumab in a Phase l/lb trial in healthy male volunteers and patients with HER-2 positive …

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Correlation Between Nottingham Prognostic Index and Adjuvant! Online Prognostic Tools in Patients With Early-Stage Breast Cancer in Mid-Western Ireland

Keith Ian Quintyne, Bernie Woulfe, John Calvin Coffey, Rajnish K. Gupta

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Correlation between anthropometric, pathologic data, and 21-gene recurrence score assay in early-stage breast cancer.

Keith Ian Quintyne, Bernie Woulfe, Linda Coate, Rajnish K. Gupta

1591 Background: Obesity or body mass index (BMI) > 30kg/m2 is a grave public health concern. Poorer outcome has been documented in obese breast cancer patients. We report the use of the Oncotype Dx Recurrence Score (RS) assay and its correlation with …

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