Ebrahim Ghafar‐Zadeh

Mechanistic Characterization of Biologically Inspired Oral Neutrophil Isolation for AI-Assisted Oral Inflammatory Load Assessment

Fatemeh Soheili, Mahdi S. M. H. Daneshvar, Navid Mohaghegh, John V. L. Nguyen et autres

Non-invasive quantitative assessment of oral inflammatory burden could complement conventional periodontal evaluation; however, current clinical methods primarily characterize disease after structural and tissue changes have occurred. In our previously reported DePerio framework, we demonstrated the feasibility of enriching oral polymorphonuclear neutrophils (oPMNs) …

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An Absorption-Based PDMS/f-CNT Mass-Capacitor for Continuous Monitoring of Fire-Derived Organic Contamination

Negar Heidari, Morteza Ghafar-Zadeh, Azadeh Amrollahi, Parviz Norouzi et autres

Firefighters are exposed to complex smoke containing volatile, semivolatile, aromatic, and particulate-associated organic contaminants that accumulate on skin, clothing, and protective equipment. Conventional gas sensors monitor only selected airborne species, while passive samplers require laboratory analysis and cannot provide continuous exposure assessment. …

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A Perspective on Direct Binary Capacitance Detectors for Decision-Driven Biochemical and Lab-on-Chip Applications: A CMOS Cross-Coupled-Based Capacitance Detector

Tayebeh Azadmousavi, Saghi Forouhi, Ebrahim Ghafar‐Zadeh

Capacitive sensors implemented in complementary metal-oxide-semiconductor (CMOS) technology are widely used in lab-on-chip (LoC), biomedical, and microfluidic systems. While most capacitive sensor interfaces are designed for high-resolution capacitance quantification, many practical applications require only binary decisions, event detection, or state discrimination. In …

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Reliability-Aware Microsystem Design; Compensation for an Ultra-Low-Power Current-Reuse LC-VCO

Tayebeh Azadmousavi, Ebrahim Ghafar‐Zadeh

Aggressive technology scaling has led to a significant increase in manufacturing process variations and transistor aging effects, which critically degrade the performance of radio frequency (RF) circuits. These reliability challenges are particularly pronounced in voltage-controlled oscillators (VCOs), where phase noise and operating …

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Electrochemical Characterization of Water–Oil Interfaces in the Presence of Nanoparticles for Enhanced Oil Recovery

Azadeh Amrollahi Biyouki, Samaneh Bovard, Negar Heidari, Mehdi Amrollahi Biouki et autres

Enhanced oil recovery (EOR) critically depends on understanding and controlling electrostatic phenomena at the oil–water–rock interface, where interfacial charge governs key recovery mechanisms in porous media. To date, no practically applicable methodology has been reported for the direct determination of interfacial charge, …

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Cap‐oPMN: Oral Inflammatory Load Quantification Using Capillary Microfluidics and Automated Image Processing

Mohsen Hassani, Azam Zare, Fatemeh Soheili, S. M. Mahdi H. Daneshvar et autres

ABSTRACT Quantifying oral polymorphonuclear neutrophils (oPMNs) is a clinically validated approach for assessing periodontal inflammation. However, current methods, such as manual hemocytometry and flow cytometry, are time‐consuming (>3 h), require invasive sampling, and depend on staining and complex instrumentation, making them unsuitable …

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Complementary metal-oxide-semiconductor (CMOS) time of evaporation measurement system for binary chemical monitoring

Ebrahim Ghafar‐Zadeh, Saghi Forouhi, Hamed Osouli Tabrizi, Abbas Panahi et autres

Accurate, real-time analysis of binary liquid mixtures is essential in chemical sensing, especially for miniaturized, low-cost applications. We present a complementary metal-oxide-semiconductor (CMOS)-based platform-ITEMS (Integrated Time-of-Evaporation Measurement System)-designed to monitor binary mixtures via high-resolution capacitive sensing of evaporation dynamics. ITEMS employs an …

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A High-Efficiency SoC for Next-Generation Mobile DNA Sequencing

Abel Beyene, Zhongpan Wu, Yunus Dawji, Karim Hammad et autres

Hand-sized Deoxyribonucleic acid (DNA) sequencing machines are of growing importance in several life sciences fields as their small footprints enable a broader range of use cases than their larger, stationary counterparts. However, as currently designed, they lack sufficient embedded computing to process …

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A novel label-free EC aptasensor for early detection of H9N2 influenza using FFT-square wave voltammetry and validated by molecular docking

Negar Heidari, Nogol D. Moghaddam, Sharmin Kharrazi, Jahan Bakhsh Ghasemi et autres

H9N2 avian influenza threatens global poultry production and human health through cross-species transmission and its role as a genetic reservoir for emerging influenza strains, underscoring the need for rapid and reliable early detection.

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A Novel Capacitive Nanomaterial-Based Sensor for Total Fire-Extracted Gas Monitoring in Firefighting Applications

Morteza Ghafar-Zadeh, N. Heidari, A. Amrollahi Biyouki, Yasaman Tahernezhad et autres

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DePerio: Innovative Deep Learning-Based Framework for Periodontal Disease Diagnosis and Severity Evaluation Using Saliva Samples

Mahdi Amrollahi Biouki, Fatemeh Soheili, Niloufar Delfan, Negin Masoudifar et autres

Recent research has identified salivary oral polymorphonuclear neutrophils (oPMNs) as reliable cellular biomarkers for monitoring the progression of periodontal disease (PD). While conventional diagnostic tools such as periodontal probing and radiographic imaging are effective at detecting advanced disease stages, they lack the …

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A CMOS Time-of-Evaporation Measurement Technique for Binary Chemical Solvent Monitoring

Saghi Forouhi, Hamed Osouli Tabrizi, Abbas Panahi, Yasaman Tahernezhad et autres

This paper introduces a novel Complementary Metal-Oxide-Semiconductor (CMOS)-based sensing mechanism for measuring the Time of Evaporation (ToE) of binary chemical solvents. Utilizing an integrated CMOS capacitive sensor, the system detects evaporation from micro-liter volumes of chemical solvents deposited on the surface of …

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