Mikihito Kajiya

Developmental Odontogenic Cyst With Characteristic Features of Glandular Odontogenic Cyst and Odontogenic Keratocyst

Nanako Kataoka, Yasuyuki Asada, Taeko Fukutani, Yukina Kobayashi et autres

The authors declare no conflicts of interest. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the …

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Bio3D graft engineered from human mesenchymal stromal cells/extracellular complexes facilitate periodontal tissue regeneration

Hiroki Yoshii, Mai Yoshino, Masayuki Suzuki, Hisakatsu Sone et autres

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Brain-derived neurotrophic factor promotes bone regeneration in a canine model of peri-implantitis

Shoko Kono, Shinya Sasaki, Shinji Matsuda, Katsuhiro Takeda et autres

PURPOSE: The present study aims to determine whether the brain-derived neurotrophic factor (BDNF)/high-molecular-weight hyaluronic acid (HMW-HA) complex could regenerate bone around implants lost due to peri-implantitis. METHODS: Dogs had their three premolars extracted, and three implants were placed on each side. After …

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Editorial: Stem cells in oral cavity: from development to regeneration, Volume II

Takehito Ouchi, Giovanna Orsini, Mikihito Kajiya, Anne George

EDITORIAL article Front. Cell Dev. Biol., 28 April 2023Sec. Stem Cell Research Volume 11 - 2023 | https://doi.org/10.3389/fcell.2023.1207744

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Periapical lesion following Cnm-positiveStreptococcus mutanspulp infection worsens cerebral hemorrhage onset in an SHRSP rat model

Yuri Taniguchi, Kazuhisa Ouhara, Masae Kitagawa, Keiichi Akutagawa et autres

Cerebral hemorrhage severely affects the daily life of affected individuals. Streptococcus mutans and its adhesion factor Cnm increase the adverse effects of cerebral hemorrhages. However, the mechanism by which Cnm-positive bacteria migrate from apical lesions to cerebral hemorrhage sites is unclear. Therefore, …

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Microbial differences between active and remission peri-implantitis

Yuhei Hashimoto, Shinsuke Okada, Keisuke Yasuda, Maiko Kawagoe et autres

Peri-implantitis has a polymicrobial etiology and is a major cause of dental implant loss. Various clinical protocols for its prevention and treatment have been proposed; however, some cases show a rapid progression with non-resolving clinical symptoms. To clear a means of differentiating …

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Editorial: Stem Cells in Oral Cavity: From Development to Regeneration

Takehito Ouchi, Giovanna Orsini, Anne George, Mikihito Kajiya

Craniofacial stem/progenitor cells are central research topics in the dental field (Yu et al., 2021; Fan et al.).A tool for tissue engineering and regenerative therapy has received medical and scientific attention.Several studies confirmed that intraoral mesenchymal stem/stromal cells (MSCs) derived from craniofacial …

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Microbial Differences Between Progressive and Stable Peri-Implantitis

Yuhei Hashimoto, Shinsuke Okada, Keisuke Yasuda, Maiko Kawagoe et autres

Abstract Peri-implantitis has a polymicrobial etiology and is a major cause of dental implant loss. Various clinical protocols for its prevention and treatment have been proposed; however, some cases show a rapid progression with non-resolving clinical symptoms. To clear a means of …

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Basic research on cytokine and cell therapy to establish a novel promising strategy for periodontal tissue regeneration

Mikihito Kajiya

Periodontitis is an inflammatory disease attributed to host immune responses to periodontal pathogenic bacteria, characterized by destruction of periodontal tissues, including the cementum, periodontal ligament, and alveolar bone. If left untreated, periodontitis can result in irreversible tissue damage, leading to tooth loss. …

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External cervical resorption detected via cone‐beam computed tomography in a patient with myelin oligodendrocyte glycoprotein antibody–associated disease: A case report

Syuichi Munenaga, Momoko Usuda, Kazuhisa Ouhara, Yuta Maetani et autres

External cervical resorption may occur in patients with MOG antibody-associated disease, which is clearly detected on cone-beam computed tomography. Therefore, dental screening is essential for these patients before initiating bisphosphonate therapy. Larger sample sizes are crucial to determine any possible association between …

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Involvement of Rac1 in macrophage activation by brain-derived neurotrophic factor

Shinya Sasaki, Katsuhiro Takeda, Kazuhisa Ouhara, Satomi Shirawachi et autres

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Predictors of early postoperative pneumonia after oncologic surgery with the patients receiving professional oral health care: A prospective, multicentre, cohort study

Shinichi Nozaki, Yasuhiko Tsutsumi, Yoshito Takasaki, Hiromasa Yoshikawa et autres

This study was a prospective, multicentre, cohort study on 685 patients who had undergone oncologic surgery. The patients were divided into two groups according to the presence or absence of postoperative pneumonia. The two groups were compared with respect to their background, …

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