Basic research on cytokine and cell therapy to establish a novel promising strategy for periodontal tissue regeneration

Le résumé fourni par la source

Periodontitis is an inflammatory disease attributed to host immune responses to periodontal pathogenic bacteria, characterized by destruction of periodontal tissues, including the cementum, periodontal ligament, and alveolar bone. If left untreated, periodontitis can result in irreversible tissue damage, leading to tooth loss. Thus, periodontal treatment is aimed at controlling bacterial infection. However, while elimination of infection can attenuate the inflammatory condition and interrupt the progression of tissue destruction, it is rarely effective at inducing periodontal tissue regeneration. Importantly, after periodontal treatment, patients are prone to recurrent periodontitis due to reduced cleanability caused by a disrupted gingival line and secondary occlusal damage resulting from lack of supportive tissue. Accordingly, for obtaining full recovery from periodontal disease, successful periodontal tissue regenerative therapy is required.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.