Xiaojiang Duan

Epidemiology, Co-infections, and Macrolide Resistance of Mycoplasma pneumoniae infection in Hangzhou, China: A Multicenter Study Analysis

Yi Wang, 蒋龙芳, Jing Wang, Xiaoxin Zhang et autres

cn (code pays fourni par la source)

A Highly Sensitive PSMA‐Targeted Ratiometric NIR Probe for Rapid Imaging of Prostate Cancer Acidity in Living Mice

Xuekang Cai, Jingming Zhang, W Q Huang, Xiaojiang Duan et autres

ABSTRACT Acidic extracellular pH (pHe), a hallmark of the solid tumor microenvironment, is closely associated with increased tumor malignancy and therapy resistance. However, the real‐time, noninvasive visualization of dynamic pHe changes in vivo remains a formidable technical challenge. In this study, we …

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Supplementary Table S1. Macrolide resistance mutation screening results from 2020 to 2024 in Hangzhou

Yi Wang, Liangliang Huo, Jing Wang, Xiaoxin Zhang et autres

This dataset contains the binary (positive/negative) results of Mycoplasma pneumoniae23S rRNA A2063G and A2064G mutation screening from 10,430 clinical specimens collected in Hangzhou, China, between 2020 and 2024. No DNA or RNA sequencing data were generated; the data were obtained from routine …

Supplementary Table S1. Macrolide resistance mutation screening results from 2020 to 2024 in Hangzhou

Yi Wang, Liangliang Huo, Jing Wang, Xiaoxin Zhang et autres

This dataset contains the binary (positive/negative) results of Mycoplasma pneumoniae23S rRNA A2063G and A2064G mutation screening from 10,430 clinical specimens collected in Hangzhou, China, between 2020 and 2024. No DNA or RNA sequencing data were generated; the data were obtained from routine …

Predicting Neoadjuvant Response of Breast Cancer at two 18F‑FDG PET/CT scanners with Radiomics model based on Combat Algorithm and Ratio Features

Gao Y, Caixia Wu, Xiaojuan Zhu, Lei Yin et autres

cn (code pays fourni par la source)

Ternary classification prediction and heterogeneity quantification for HER2-Zero, -low, and -positive in breast cancer using HER2-targeted PET/CT imaging

Yuan Gao, Lei Yin, Xiaojiang Duan, Qian Liu et autres

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[ 68 Ga]Ga-PG2-2FAPI: A DPro-Gly-Modified Dimeric FAPI Probe with Enhanced Tumor Uptake and Retention

Qing Ruan, Yuhao Jiang, Zuojie Li, Xiaojiang Duan et autres

In this study, a novel fibroblast activation protein (FAP) targeting ligand based on the bivalent DPro-Gly structure, DOTA-PG2-2FAPI, was designed and synthesized. Molecular docking analysis revealed that compared with monomeric FAPI-46, DOTA-PG2-2FAPI had a higher binding score (−15.00 vs −11.36), with an …

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Construction and Evaluation of Guanylyl Cyclase C–Specific Antibody for Noninvasive Diagnosis and Targeted Therapy of Colorectal Cancer

Zhuona Rong, Hongjin Liu, Xia Teng, Lin Chen et autres

Colorectal cancer (CRC) remains the leading cause of cancer mortality worldwide despite therapeutic advances. Guanylyl cyclase C (GUCY2C), an intestinal epithelial receptor, is emerging as a promising diagnostic and therapeutic target for CRC. Thus, we are interested in developing a monoclonal antibody …

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Noninvasive Evaluation of HER2 Expression and Heterogeneity in Urothelial Carcinoma on 68Ga-HER2-affibody PET/CT

Zihao Tao, Xueqi Chen, Q. Tang, Xiaojiang Duan et autres

PURPOSE: Human epidermal growth factor receptor 2 (HER2) is a promising therapeutic target in urothelial carcinoma (UC). We aimed to evaluate the feasibility of 68Ga-HER2 affibody PET/CT in assessing HER2 expression and tumor heterogeneity, and to explore its utility for guiding HER2-targeted …

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Supplementary Video S2C from First-in-Human Study of the Radioligand 68Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma

Xiaojiang Duan, Lei Xia, Zhuochen Zhang, Yanan Ren et autres

40 min full dynamic Total-body PET imaging of Patient 6

Supplementary Video S2A from First-in-Human Study of the Radioligand 68Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma

Xiaojiang Duan, Lei Xia, Zhuochen Zhang, Yanan Ren et autres

40 min full dynamic Total-body PET imaging of Patient 1

Supplementary Table S4 from First-in-Human Study of the Radioligand 68Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma

Xiaojiang Duan, Lei Xia, Zhuochen Zhang, Yanan Ren et autres

68Ga-N188 normal-organ absorbed doses in male (μGy/MBq, mean ± SD).