Kefen Wang

Semi-automated strain engineering and screening in the thermophilic fungus Myceliophthora thermophila for recombinant protein production

Chaohui Gong, Xinyu Yang, Xiucai Zhao, Fufan Gou et autres

ABSTRACT Thermophilic filamentous fungi are widely used for cellulase production at elevated temperatures; however, efficient recombinant protein production in these organisms remains limited because construction and screening of large transformant populations remain difficult. Here, Myceliophthora thermophila was engineered into a thermophilic fungal …

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Development of an efficient heterologous protein expression platform in Aspergillus niger through genetic modification of a glucoamylase hyperproducing industrial strain

Fufan Gou, Dandan Liu, Chao Gong, Kefen Wang et autres

BACKGROUND: Aspergillus niger is widely used in industrial enzyme production due to its strong secretion capacity and the status of generally recognized as safe (GRAS). However, heterologous protein expression in A. niger is frequently constrained by high levels of background endogenous protein …

cn (code pays fourni par la source)

[Exploring the Causal Relationship Between Circulating Immune Cells and Autoimmune Hepatitis Through Mendelian Randomization Analysis].

Song Leng, Kefen Wang, Yujun Shi, Cheng Deng

Objective: To elucidate the causal relationship between specific immune cells and autoimmune hepatitis (AIH) using a two-sample Mendelian randomization (MR) approach. Methods: A bidirectional MR analysis was conducted using data from large publicly accessible Genome-Wide Association Study (GWAS) databases. The inverse variance …

Machine learning models predicts risk of proliferative lupus nephritis

Panyu Yang, Zhongyu Liu, Fenjian Lu, Yulin Sha et autres

Objective: This study aims to develop and validate machine learning models to predict proliferative lupus nephritis (PLN) occurrence, offering a reliable diagnostic alternative when renal biopsy is not feasible or safe. Methods: This study retrospectively analyzed clinical and laboratory data from patients …

cn (code pays fourni par la source)

WNT16 as a promising biomarker for systemic lupus erythematosus and its role in regulating cell proliferation and apoptosis

Kefen Wang, Yiheng Jiang, Jianzhao Zhai, Pin Zhang et autres

OBJECTIVES: To investigate the expression and function of WNT16, a member of the WNT family protein, in the context of systemic lupus erythematosus (SLE). METHODS: WNT16 expression was assessed in peripheral blood mononuclear cells (PBMCs) from 35 SLE patients and 25 healthy …

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Manipulation of an α-glucosidase in the industrial glucoamylase-producing Aspergillus niger strain O1 to decrease non-fermentable sugars production and increase glucoamylase activity

Wenzhu Guo, Dandan Liu, Jingen Li, Wenliang Sun et autres

Dextrose equivalent of glucose from starch hydrolysis is a critical index for starch-hydrolysis industry. Improving glucose yield and decreasing the non]-fermentable sugars which caused by transglycosylation activity of the enzymes during the starch saccharification is an important direction. In this study, we …

cn (code pays fourni par la source)

Design of non-motorized lanes on urban roads

Yufan Ren, Kefen Wang, Xin‐Sheng Yao

Non-motor vehicle traffic is an important part of the road traffic system, which is one of the various ways of travel for residents. It has a great advantage in short-distance travel and brings great convenience to people's daily travel. Therefore, the design …

CHAPTER IX PAINTINGS AND MURALS OF THE SUI AND TANG DYNASTIES

Shouxiang Chen, Yi Li, Junxiang Liu, Kaiyi Qi et autres

CHAPTER II MUSIC AND DANCE OF THE PREFECTURES, COUNTIES, DEFENSE COMMANDS AND THE LITERATI; RICH DIVERSITY IN FOLK MUSIC, DANCE AND VARIETY SHOWS

Shouxiang Chen, Yi Li, Junxiang Liu, Kaiyi Qi et autres

CHAPTER II MUSIC AND DANCE OF THE PREFECTURES, COUNTIES, DEFENSE COMMANDS AND THE LITERATI; RICH DIVERSITY IN FOLK MUSIC, DANCE AND VARIETY SHOWS was published in Volume 3 A General History of Chinese Art on page 69.

CHAPTER IV BRILLIANT ACHIEVEMENTS IN THE MUSICAL ARTS

Shouxiang Chen, Yi Li, Junxiang Liu, Kaiyi Qi et autres

CHAPTER III THE GLORY OF THE ART OF DANCE

Shouxiang Chen, Yi Li, Junxiang Liu, Kaiyi Qi et autres

CHAPTER XI ARCHITECTURE AND CRAFT ARTS OF THE SUI AND TANG DYNASTIES

Shouxiang Chen, Li Yi, Junxiang Liu, Kaiyi Qi et autres