Taeseok Kang

Direct Catalytic Deaminative Cyanation of Aliphatic Primary Amines

Jiang‐Hao Xue, Shuang Lin, Jiawu Huang, Taeseok Kang et autres

The cyano group is an important and versatile functional group in medicinal chemistry. It is an important target in its own right while also serving as a precursor to other valuable motifs including aminomethyl and carboxamide groups. However, direct deaminative cyanation of …

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Enzyme-free chemical DNA ligation via amine-crosslinker-mediated DNA assembly for miRNA detection

Doyeon Lim, Zeeshan Haider, Hyo-Jin Lim, Won Jin Lee et autres

MicroRNAs (miRNAs) serve as crucial disease biomarkers, with quantitative reverse transcription PCR (RT-qPCR) remaining the gold standard for their detection. However, current methods rely on temperature-sensitive enzymes that introduce variability and storage challenges. Here, we present enzyme-free miRNA-splinted DNA ligation strategies utilizing …

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High ratio carbon nanotube-carboxymethyl cellulose composite grid for Joule heating device

Won Jin Lee, Doyeon Lim, Taeseok Kang, Changjae Lee et autres

This study reports on the fabrication and characterization of a carbon nanotube (CNT)-carboxymethyl cellulose (CMC) composite grid structure for transparent Joule heating electronic applications. Using flexible polydimethylsiloxane mold, we fabricated a large-scale 4-inch CNT-CMC composite grid with 500 µm line pattern. The …

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Polymerase Elongation onto Patterned DNA for Random Accessed DNA Data Storage

Taeseok Kang, Doyeon Lim, Won Jin Lee, Youngjun Song

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Elastic conductive CNT/Ecoflex nanocomposites for tactile sensing

Won Jin Lee, Chan-Hyeok Lee, Taeseok Kang, Youngjun Song

This study presents fabrication and analysis of carbon nanotube (CNT)/Ecoflex composites with characteristics of balanced conductivity, flexibility and mechanical robustness. We developed uniform composites using a low-viscosity CNT/Ecoflex suspension combined with a solvent evaporation technique. The electrical resistance and strain characteristics of …

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Amine-to-Amine Deoxyribonucleic Acid Conjugation Process on Gold Surfaces for Electric Field-Assisted Hybridization

Doyeon Lim, Seunghwan Noh, Taeseok Kang, Navchtsetseg Nergui et autres

DNA immobilization on metal surfaces is widely used for DNA hybridization applications in biotechnology and nanotechnology. Stable DNA binding properties are essential to the functionality and accuracy for these DNA-based applications. We developed an optimized protocol utilizing amine-functionalized surfaces and demonstrated enhanced …

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The multiple fluorescent multi-bit DNA memory encoding system

Navchtsetseg Nergui, Jong-Do Kim, Doyeon Lim, Won Jin Lee et autres

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Programmable DNA-Based Boolean Logic Microfluidic Processing Unit

Won Jin Lee, Minsang Yu, Doyeon Lim, Taeseok Kang et autres

As molecular computing materials, information-encoded deoxyribonucleic acid (DNA) strands provide a logical computing process by cascaded and parallel chain reactions. However, the reactions in DNA-based combinational logic computing are mostly achieved through a manual process by adding desired DNA molecules in a …

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DeepHandsVR: Hand Interface Using Deep Learning in Immersive Virtual Reality

Taeseok Kang, Minsu Chae, Eunbin Seo, Mingyu Kim et autres

This paper proposes a hand interface through a novel deep learning that provides easy and realistic interactions with hands in immersive virtual reality. The proposed interface is designed to provide a real-to-virtual direct hand interface using a controller to map a real …

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Development and Validation for Determination of Preservatives in Spices using HPLC-MS/MS and GC-MS

Sang-Soon Yun, Do-Yeon Lim, Sang‐Jin Lee, Gunyoung Lee et autres

Analysis of dutasteride in human serum by LC-MS/MS

Hye-Seon Nam, Kyong‐Hee Nam, Su-Hee Jung, Jangwoo Lee et autres

본 연구는 혈청 중 두타스테라이드의 확인과 정량을 위하여 LC-ESI-MS/MS를 이용한 신뢰성 있는 분석법을 개발하고, 분석방법의 타당도를 검증하고자 수행하였다. 내부표준물질인 베클로메타손을 첨가한 혈청을 methyl tert-butyl ether (MTBE)를 사용하여 액체상추출법(liquid-liquid extraction, LLE)으로 추출하였다. LC-MS/MS의 양이온 모드에서 MRM(multiple reaction monitoring)방법으로 확인한 두타스테라이드와 베클로메타손의 mass transition은 …

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Determination of finasteride in human serum by LC-MS/MS

Hye-Seon Nam, Kyong‐Hee Nam, Su-Hee Jung, Jangwoo Lee et autres

본 연구는 LC-ESI-MS/MS를 이용하여 혈청 중의 피나스테라이드의 분석법을 확립하고, 밸리데이션을 통하여 분석방법의 타당도를 검증하였다. 혈청에 내부표준물질로 베클로메타손을 첨가한 후 methyl tert-butyl ether (MTBE)을 사용하여 액체상추출법(liquid-liquid extraction, LLE)으로 전처리하였다. LC-MS/MS의 양이온 모드에서 피나스테라이드와 베클로메타손의 MRM (multiple reaction monitoring) mass transition은 각각 m/z 373.2 …

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