Cheryl Yi‐Pin Lee

Nexus of virus and brain: recent advances in flavivirus and enterovirus neuro-infection

Cheryl Yi‐Pin Lee, Fok‐Moon Lum

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Polystyrene nanoplastics promote neurodegeneration by catalyzing TDP43 hyperphosphorylation

Winanto Ng, Wai Hon Chooi, Cheryl Yi‐Pin Lee, Wen‐Jeng Ho et autres

ABSTRACT The ubiquity of polystyrene nanoplastics (PS-NPs) in our environment raises substantial concerns about their potential impact on human health. Recent studies have shown that PS-NPs cross the blood-brain-barrier and accumulate in the central nervous system (CNS), raising the concerns on the …

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Enterovirus-A71 preferentially infects and replicates in human motor neurons, inducing neurodegeneration by ferroptosis

Wai Hon Chooi, Winanto Winanto, Yingying Zeng, Cheryl Yi‐Pin Lee et autres

Enterovirus A71 (EV-A71) causes Hand, Foot, and Mouth Disease and has been clinically associated with neurological complications. However, there is a lack of relevant models to elucidate the neuropathology of EV-A71 and its mechanism, as the current models mainly utilize animal models …

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Label-Free and High-Throughput Removal of Residual Undifferentiated Cells From iPSC-Derived Spinal Cord Progenitor Cells

Tan Dai Nguyen, Wai Hon Chooi, Hyungkook Jeon, Jiahui Chen et autres

The transplantation of spinal cord progenitor cells (SCPCs) derived from human-induced pluripotent stem cells (iPSCs) has beneficial effects in treating spinal cord injury (SCI). However, the presence of residual undifferentiated iPSCs among their differentiated progeny poses a high risk as these cells …

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MP12-11 EVALUATION OF BLADDER CANCER PATIENTS’ UTILIZATION OF UROLOGIC TELEHEALTH SERVICES

Steven B. Goldenthal, Tasha Posid, Victor Heh, Dairon Denis-Diaz et autres

You have accessJournal of UrologyCME1 Apr 2023MP12-11 EVALUATION OF BLADDER CANCER PATIENTS’ UTILIZATION OF UROLOGIC TELEHEALTH SERVICES Steven Goldenthal, Tasha Posid, Victor Heh, Dairon Denis-Diaz, Hafsa Asif, Chase Arnold, Henry Gold, Amara Ndumele, Sabrina Amin, Matthew Lierz, Vivian Xu, Tyler Cronin, Aliza …

CD8+ T Cells Trigger Auricular Dermatitis and Blepharitis in Mice after Zika Virus Infection in the Absence of CD4+ T Cells

Cheryl Yi‐Pin Lee, Guillaume Carissimo, Teck‐Hui Teo, Samuel Jia Ming Tong et autres

Zika virus (ZIKV) became a public health concern when it re-emerged in 2015 owing to its ability to cause congenital deformities in the fetus and neurological complications in adults. Despite extensive data on protection, the interplay of protective and pathogenic adaptive immune …

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Label-free and high-throughput removal of residual undifferentiated cells from iPSC-derived spinal-cord progenitor cells

Tan Dai Nguyen, Wai Hon Chooi, Hyungkook Jeon, Jiahui Chen et autres

Summary The transplantation of spinal cord progenitor cells (SCPCs) derived from human induced pluripotent stem cells (iPSCs) has beneficial effects on treating spinal cord injury (SCI). However, the presence of residual undifferentiated iPSCs amongst their differentiated progeny poses a high risk as …

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Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections

Yun Shan Goh, Siew‐Wai Fong, Pei Xiang Hor, Siti Naqiah Amrun et autres

Introduction: COVID-19 has a wide disease spectrum ranging from asymptomatic to severe. While humoral immune responses are critical in preventing infection, the immune mechanisms leading to severe disease, and the identification of biomarkers of disease progression and/or resolution of the infection remains …

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Modulating neuroinflammation through molecular, cellular and biomaterial‐based approaches to treat spinal cord injury

Cheryl Yi‐Pin Lee, Wai Hon Chooi, Shi‐Yan Ng, Sing Yian Chew

The neuroinflammatory response that is elicited after spinal cord injury contributes to both tissue damage and reparative processes. The complex and dynamic cellular and molecular changes within the spinal cord microenvironment result in a functional imbalance of immune cells and their modulatory …

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Cheryl Yi‐Pin Lee, Wai Hon Chooi, Shi‐Yan Ng, Sing Yian Chew

Enhancing Recovery After Major Bladder Cancer Surgery: Comprehensive Review and Assessment of Application of the Enhanced Recovery After Surgery Guidelines

Judith Stangl‐Kremser, Luca Lambertini, Fabrizio Di Maida, Alexander Martinez‐Fundichely et autres

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Malaria abrogates O’nyong–nyong virus pathologies by restricting virus infection in nonimmune cells

Anthony Torres‐Ruesta, Teck‐Hui Teo, Yi‐Hao Chan, Siti Naqiah Amrun et autres

O’nyongnyong virus (ONNV) is a re-emerging alphavirus previously known to be transmitted by main malaria vectors, thus suggesting the possibility of coinfections with arboviruses in co-endemic areas. However, the pathological outcomes of such infections remain unknown. Using murine coinfection models, we demonstrated …

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