Quanling Zhang

An Indigenous Pseudomonas chlororaphis-like Isolate M6 Is Associated with Reduced Cotton Damping-Off and Partial Redox–Phenylpropanoid Molecular Profiles

Yingming Wei, Qiuyue Zhao, Xiaolei Cao, Quanling Zhang et autres

Cotton damping-off caused by Rhizoctonia solani restricts seedling establishment, and locally adapted biocontrol isolates are potential components of sustainable disease management. This study evaluated Pseudomonas chlororaphis-like isolate M6 and tested whether molecular profiles in M6-protected plants differed from those in Pathogen-infected plants …

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A Comprehensive Review of Metal-Based Nanozymes for ROS Scavenging and Therapeutic Applications in Osteoarthritis

H. M. Liu, Tongtong Li, Siqi Zhao, Xiaomei Qiao et autres

Reactive oxygen species (ROS) play a crucial role in the occurrence and development of osteoarthritis (OA). The homeostasis of the joint environment becomes imbalanced when joints are affected by various adverse factors, such as long-term excessive wear, trauma, and aging. Excessive accumulation …

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Advanced 3D/4D Bioprinting of Flexible Conductive Materials for Regenerative Medicine: From Bioinspired Design to Intelligent Regeneration

Kuikui Zhang, Lezhou Fang, Can Xu, Weiwei Zhou et autres

Regenerative medicine is increasingly leveraging the synergies between bioinspired conductive biomaterials and 3D/4D bioprinting to replicate the native electroactive and hierarchical microenvironments essential for functional tissue restoration. However, a critical gap remains in the intelligent integration of these technologies to achieve dynamic, …

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Multi-objective optimization for sustainable dimethyl oxalate synthesis: A plant-wide framework balancing economic benefits and carbon emissions

Shida Gao, Cuimei Bo, Guo Yu, Quanling Zhang et autres

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First Report of Phelipanche aegyptiaca Parasitizing Cotyledon tomentos a in China

Hailong Yu, Juan Du, Yuzhong Ren, Xiaolei Cao et autres

Cotyledon tomentosa Harv. (Crassulaceae), commonly known as bear's paw, is a popular succulent prized for its significant ornamental and economic value. In March 2024, however, a root holoparasite was discovered infecting approximately 25% of potted C. tomentosa plants in Shihezi, Xinjiang, China …

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Zebrafish ZDHHC11 palmitoylates STING to potentiate antiviral immune response

Tenglong Yu, Meifeng Li, Hongying Zhang, Jihuan Hu et autres

In mammals, the activation of stimulator of interferon gene (STING), a pivotal adaptor protein mediating type I interferon (IFN-I) induction upon DNA virus infection, is regulated by palmitoylation. This post-translational modification is catalyzed by zinc finger DHHC domain-containing palmitoyltransferases (ZDHHCs). However, the …

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ISGylation of zebrafish STING at lysines 221 and 276 activates innate immunity

Hongying Zhang, Kaiwen Zhao, Quanling Zhang, Tingting Yu et autres

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RBCK1 enhances antiviral response through promoting K63-linked polyubiquitination of IRF7 in Carassius auratus var. Pengze

Quanling Zhang, Tingting Yu, Zhongwei Wang, Jingen Xu et autres

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Ctenopharyngodon idellus Mex3C activates the innate immune by promoting the K63-linked ubiquitination of RIG-I

Tingting Yu, Chuxin Wu, Dongming Li, Xiaowen Xu et autres

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Zebrafish TDP43 positively regulates p65-mediated apoptotic pathway

Tingting Yu, Miaomiao Li, Meifeng Li, Quanling Zhang et autres

TAR DNA-binding protein 43 (TDP43) is a multifunctional RNA/DNA binding protein that serves as a hallmark of neurodegeneration in amyotrophic lateral sclerosis (ALS) and is associated with the inflammatory response related to nuclear factor κB (NF-κB) pathway. However, the relationship between TDP43 …

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ALGPT: Multi-Agent Cooperative Framework for Open-Vocabulary Multi-Modal Auto-Annotating in Autonomous Driving

Yijie Zhou, Xianhui Cheng, Quanling Zhang, Lei Wang et autres

Large Language Models (LLMs) have achieved impressive progress in decision-making and task automation for intelligent agents. However, multiple agents must cooperate to complete tasks in complex real-world applications, such as auto-annotating in autonomous driving. The primary challenges lie in how multiple agents …

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OpenAnnotate2: Multi-Modal Auto-Annotating for Autonomous Driving

Yijie Zhou, Likun Cai, Xianhui Cheng, Quanling Zhang et autres

The demand for high-quality annotated data has surged in recent years for applications driven by real-world artificial intelligence, such as autonomous driving and embodied intelligence. Consequently, the development of a tool that can assist humans in the highly automated and high-quality annotation …

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