Sáhlua Miguel Volc

Disparities in diagnosis and management of myelodysplastic syndromes in a brazilian cancer center: A comparison between public and private healthcare systems.

Arthur Gomes Oliveira Braga, Julia Curi Amarante, Humberto Villefort, Sáhlua Miguel Volc et autres

Abstract Introduction: Disparities in access to healthcare services are well-documented in Brazil, where a mixed public-private system often leads to unequal resource distribution. Prior studies have demonstrated differences in service utilization and health expenditures between the Brazilian public health system (SUS) and …

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DISPARITIES IN DIAGNOSIS AND MANAGEMENT OF MYELODYSPLASTIC SYNDROMES IN A BRAZILIAN CANCER CENTER: A COMPARISON BETWEEN PUBLIC AND PRIVATE HEALTHCARE SYSTEMS.

Antônio Mendes da Costa Braga, Sáhlua Miguel Volc, José Souto Rosa Filho, M de Mattos Nascimento

Disparities in access to healthcare services are well-documented in Brazil, where a mixed public-private system often leads to unequal resource distribution. Prior studies have demonstrated differences in service utilization and health expenditures between the Brazilian public health system (SUS) and private healthcare …

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Impactos Psicossociais e na Qualidade de Vida do Tratamento Oncológico em Crianças e Adolescentes

Clara Ignácio Pessoa Pereira, Ivan Campos Teixeira e Nascimento, Aristides Schier DA CRUZ, Sáhlua Miguel Volc et autres

Introdução: Tão importante quanto o diagnóstico e o tratamento do câncer pediátrico são os cuidados relacionados ao impacto psicossocial, educacional e emocional. Objetivo: Avaliar em crianças e adolescentes com diagnóstico de câncer os impactos psicossociais, de qualidade de vida e da presença …

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Accessing the Health Needs of Adolescents and Young Adults with Cancer in Brazil

Sáhlua Miguel Volc

Adolescents and young adult cancer patients have unique characteristics and specific needs that, when properly comprehended, can improve quality of life during and after the oncologic treatment.Objective: verify those that would be the main health needs among this group of patients.Method: cultural …

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Necessidades de saúde dos adolescentes e adultos jovens com câncer

Isabela Maria Volski, Larissa De Andrade, Rebecca Skalski Costa, Sáhlua Miguel Volc et autres

Introduction: The population of adolescents and young adults aged between 15 and 39 years old diagnosed with cancer is known as AYA (adolescent and young adults). These patients receive treatment in pediatric and adult centers that do not meet their biological and …

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Clinical impact of brachyury expression in Ewing sarcoma patients

Lucas Faria Abrahão‐Machado, Filipe Pinto, Bruno Pereira Antunes, Sáhlua Miguel Volc et autres

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Clinical and Molecular Assessment of Patients with Lynch Syndrome and Sarcomas Underpinning the Association with MSH2 Germline Pathogenic Variants

Nathália de Angelis de Carvalho, Bianca Naomi Niitsuma, Vanessa Nascimento Kozak, Felipe D’Almeida Costa et autres

Lynch syndrome (LS) is a hereditary cancer-predisposing syndrome associated most frequently with epithelial tumors, particularly colorectal (CRC) and endometrial carcinomas (EC). The aim of this study was to investigate the relationship between sarcomas and LS by performing clinical and molecular characterization of …

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XAF1 as a modifier of p53 function and cancer susceptibility

Emília M. Pinto, Bonald C. Figueiredo, Wenan Chen, Henrique C.R. Galvão et autres

The XAF1 -E134* variant increases the cancer risk for carriers of the TP53 -R337H allele.

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The Brazilian TP53 mutation (R337H) and sarcomas

Sáhlua Miguel Volc, Cíntia Regina Niederauer Ramos, Henrique de Campos Reis Galvão, Paula Silva Felicio et autres

Sarcomas represent less than 1% of all solid neoplasms in adults and over 20% in children. Their etiology is unclear, but genetic susceptibility plays an important role in this scenario. Sarcoma is central in Li-Fraumeni Syndrome (LFS), a familial predisposition cancer syndrome. …

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Loss of MTAP Expression is a Negative Prognostic Marker in Ewing Sarcoma Family of Tumors

Lucas Faria Abrahão‐Machado, Bruno Pereira Antunes, Renée Zon Filippi, Sáhlua Miguel Volc et autres

AIM: The Ewing sarcoma family of tumors (ESFT) is a group of malignant small round cell neoplasms of bones and soft tissues closely histogenetically related. Methylthioadenosine phosphorylase (MTAP) deficiency has been recently associated with increased tumor aggressiveness and poor outcomes in different …

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p53 signaling pathway polymorphisms, cancer risk and tumor phenotype in TP53 R337H mutation carriers

Gabriel S. Macedo, Igor Araújo Vieira, Fernanda Salles Luiz Vianna, Bárbara Alemar et autres

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Prevalence of BRCA1/BRCA2 mutations in a Brazilian population sample at-risk for hereditary breast cancer and characterization of its genetic ancestry

Gabriela Carvalho Fernandes, Rodrigo Augusto Depieri Michelli, Henrique C.R. Galvão, André Escremim de Paula et autres

// Gabriela C. Fernandes 1, * , Rodrigo A.D. Michelli 2, * , Henrique C.R. Galvão 2, * , André E. Paula 1 , Rui Pereira 3, 4 , Carlos E. Andrade 2 , Paula S. Felicio 5 , Cristiano P. Souza …

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