Oxana Grosu

ABSTRACT NUMBER: ESOC2026A831 NIHSS-STRATIFIED EFFICACY OF REPERFUSION STRATEGIES IN ACUTE ISCHEMIC STROKE

Adriana Arabadji, Elena Costru-Tasnic, Teacă Irina, Cătălina Gutu et autres

Abstract Background and aims The optimal selection of reperfusion strategy in acute ischemic stroke (AIS) due to large vessel occlusion remains controversial, particularly across different levels of stroke severity. Stratification by baseline NIHSS score may help refine treatment selection. Aim To compare …

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ABSTRACT NUMBER: ESOC2026A2368 ACUTE ISCHEMIC STROKE IN YOUNG ADULTS: CLINICAL CHARACTERISTICS AND OUTCOMES AT A TERTIARYSTROKE CENTER IN THE REPUBLIC OF MOLDOVA

Spinei Veronica, Levca Anastasia, Tatiana Stupac, Oxana Grosu et autres

Abstract Background and aims Acute ischemic stroke (AIS) is a leading cause of mortality and long-term disability worldwide. Recent years have shown a decreasing age at stroke onset, with rising incidence among young adults under 50 years. The aim is to analyze …

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ABSTRACT NUMBER: ESOC2026YS109 PROGNOSTIC IMPACT OF SEQUENTIAL SERUM BIOMARKERS AND MULTIMODAL CT IMAGING ON CLINICAL OUTCOMES AFTER EXTENDED-WINDOW MECHANICAL THROMBECTOMY IN ACUTE ISCHEMIC STROKE

Elena Costru-Tasnic, Olga Gavriliuc, Adriana Arabadji, Teacă Irina et autres

Abstract Background and aims Clinical outcome prognostic of acute ischemic stroke (AIS) patients undergoing mechanical thrombectomy (MT) beyond 6 hours from symptom onset remains challenging. While multimodal CT provides valuable information about brain parenchyma status, biological processes such as inflammation, hemostatic disturbances, …

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ABSTRACT NUMBER: ESOC2026A1757 FASTER IS BETTER EFFECT OF EMERGENCY DEPARTMENT INITIATED INTRAVENOUS THROMBOLYSIS ON DOOR TO NEEDLE TIME AND CLINICAL OUTCOMES IN A MOLDOVAN STROKE CENTER

Levca Anastasia, Veronica Spinei, Tatiana Stupac, Stanislav Dorosenco et autres

Abstract Background and aims Timely administration of intravenous thrombolysis (IVT) is a determinant of outcome in acute ischemic stroke. Although a door-to-needle time (DNT) of <45 minutes is recommended, this target is difficult to achieve, particularly in resource-limited healthcare systems. In 2025, …

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The value of nonfactual information in distinguishing primary from secondary headache disorders results of a Delphi study

Heiko Pohl, Thien Phu, Andreas R. Gantenbein, Hamit Genç et autres

Objective To collect pairs of nonfactual information and their interpretations and rate their usefulness in distinguishing between primary and secondary headache disorders. Background Physicians use clinical indicators such as Red Flags and ask about exposure to potential causes to differentiate primary from …

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Anorexia Nervosa: A Case Report

Ghenadie Cărăușu, Roxana Chiriță, Lilia Rotaru, Gabriela Nacu et autres

Anorexia nervosa is a mental disorder characterized by an intense fear of weight gain, significantly low body weight, and a distorted body image. The disorder is more prevalent in high-income countries and occurs most frequently among adolescent girls and young women. Identified …

Migraine care in the Eastern Europe region

Oxana Grosu, V.I. Romanenko, Lilia Rotaru, Aleksandra Radojičić et autres

Background In Eastern Europe, migraine imposes a substantial yet heterogeneous burden, ranking second among neurological disorders in disability-adjusted life years (DALYs) according to Global Burden of Disease (GBD) estimates. Methods To capture context-specific challenges, we conducted a regional case study with experts …

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The Evolution of Acute Cerebrovascular Disease Patient Management in the Post-COVID-19 Period: A Systematic Review

Diana Zețu-Buciușcan, Elena Manole, Elena Costru-Tasnic, Lilia Rotaru et autres

Stroke represents a major public health issue, causing millions of deaths annually and generating a significant burden in terms of disability. The COVID-19 pandemic profoundly influenced the management of patients with acute stroke, leading to reduced hospital admissions and delays in therapeutic …

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Management of patients with neurodegenerative diseases in the post-COVID-19 era: lessons learned and future directions

Mădălina Cebuc, Lilia Rotaru, Stela Odobescu, Ion Moldovanu et autres

Background: Neurodegenerative diseases (NDs) are progressive disorders with a major impact on autonomy and quality of life, and the COVID-19 pandemic has exacerbated their burden by limiting access to care. Objective: To synthesize post-pandemic data and clinical experience to propose directions for …

Headache characteristics attribute to acute infections in Republic of Moldova: prospective multicentric study

Cătălina Gutu, Mirabela Maximciuc, Gabriela Nacu, Galina Zolotco et autres

Introduction. Headache is a frequent symptom associated with acute infections; however, data regarding its characteristics and the risk of chronification remain limited, particularly outside the context of COVID-19 infection. Materials and methods. The national cohort from the Republic of Moldova included 40 …

The evolution of patient management in infectious and autoimmune diseases in the post-COVID-19 era

Cătălina Gutu, Evelina Sabanov, Oxana Grosu, Elena Manole et autres

Aim: To examine the changes implemented and emerging trends in managing patients with autoimmune and infectious neurologic pathology in the postCOVID-19 period, with focus on clinical and epidemiological experience. Materials and Methods: A systematic literature review was carried out following PRISMA criteria, …

Risk factors of stroke in young adults: a retrospective cohort study

Gabriela Nacu, Stela Odobescu, Ion Moldovanu, Galina Corcea et autres

Introduction: The incidence of ischemic stroke in young adults (defined by several studies as the population aged 1850) accounts for approximately 15% - 18% of the total number of ischemic stroke cases. Many studies have highlighted the significant impact of traditional vascular …