UbC4 from Leishmania is a Druggable E2 Ubiquitin Conjugating Enzyme: Structural Basis and Fragment Hits for Future E2-Recruiting PROTAC Development
Cécile Exertier, Lorenzo Antonelli, Anastasia Liuzzi, Marcus Ruffa et autres
0 citationsACS Omega
Cécile Exertier
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45Publications signalées
452Citations signalées
2Affiliations récentes
Institutions déclarées
Domaines associés
Hemoglobin structure and functionResearch on Leishmaniasis StudiesProtein Structure and DynamicsTrypanosoma species research and implicationsErythrocyte Function and Pathophysiology
Publications récentes
Second Generation of 2,2′-Di(indol-3-yl)ethanamines as Antileishmanial Agents: Phenotypic Hit Identification and Pharmacophore Studies
Gian Marco Elisi, Antonio Gkoutzamanis, Sara Maestrini, Cécile Exertier et autres
0 citationsACS Infectious Diseases
Integrated Computational and Experimental Discovery of a Selective Indole-Based Hit Targeting Leishmania infantum Trypanothione Reductase through a Dual-Site Binding Mode
Antonio Curcio, Grazia Pavia, Roberta Rocca, Vittorio Brufani et autres
0 citationsZenodo (CERN European Organization for Nuclear Research)
Integrated Computational and Experimental Discovery of a Selective Indole-Based Hit Targeting Leishmania infantum Trypanothione Reductase through a Dual-Site Binding Mode
Antonio Curcio, Grazia Pavia, Roberta Rocca, Vittorio Brufani et autres
0 citationsZenodo (CERN European Organization for Nuclear Research)
A Selective and Safe Indole-Based Lead Compound Targeting LiTR for Anti-Leishmania Therapy: A One Health–Driven Discovery
Antonio Curcio, Grazia Pavia, Roberta Rocca, Vittorio Brufani et autres
0 citationsZenodo (CERN European Organization for Nuclear Research)
ITABAG: Crystallographic investigations on macromolecules for a structure-based approach to One Health
Rocco Caliandro, Antonella Costanzo, Cécile Exertier, Ilaria Silvestri
0 citationsEuropean Synchrotron Radiation Facility
Antileishmanial activity of gold(I) compounds containing triphenylphosphine ligands against Leishmania amazonensis: impacts on mitochondrial bioenergetics and trypanothione reductase activity
Marcus Sávio Araújo Garcia, Vitor Klipel Silva Bertolini, Cécile Exertier, Fernanda Ramos Gadelha et autres
0 citationsResearch Square
Disrupting Leishmania redox homeostasis: Mechanistic insights into a platinum-based antileishmanial complex
Marcus Sávio Araújo Garcia, Vitor K. S. Bertolini, Fernanda Ramos Gadelha, Cécile Exertier et autres
1 citationJournal of Inorganic Biochemistry
Cryo-EM structure of the ligand-free sigma-1 receptor unveils a possible mechanism for its oligomerization
Vittorio Brufani, Lorenzo Antonelli, Giancarlo Tria, Gaetano D'Urso et autres
0 citationsSSRN Electronic Journal
Molecular Insights into IAHSP: Influence of the R1611W Mutation on the VPS9 Domain of Alsin
Marcello Miceli, Cécile Exertier, Elena Gugole, Beatrice Vallone et autres
0 citationsACS Omega
Specialty grand challenges in theoretical modeling, structure prediction and design
0 citationsFrontiers in Chemical Biology
Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis
Cécile Exertier, Lorenzo Antonelli, Vittorio Brufani, Gianni Colotti et autres
2 citationsFrontiers in Chemical Biology
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