Katsuji Torimoto

Tofogliflozin long-term effects on atherosclerosis progression and major clinical parameters in patients with type 2 diabetes mellitus lacking a history of cardiovascular disease: a 2-year extension study of the UTOPIA trial

Naoto Katakami, Tomoya Mita, Hidenori Yoshii, Toshihiko Shiraiwa et autres

BACKGROUND: This study aimed to assess the long-term effects of tofogliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, on atherosclerosis progression and major clinical parameters in patients with type 2 diabetes lacking an apparent history of cardiovascular disease. METHODS: This was a prospective …

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The Influence of Tofogliflozin on Treatment-Related Quality of Life in Patients with Type 2 Diabetes Mellitus

Naoto Katakami, Tomoya Mita, Hidenori Yoshii, Toshihiko Shiraiwa et autres

INTRODUCTION: Treatment-related quality of life (QOL) is an important aspect of diabetes management. We evaluated the influence of a sodium-glucose cotransporter 2 (SGLT2) inhibitor, tofogliflozin, on treatment-related QOL in Japanese patients with type 2 diabetes mellitus (T2DM). METHODS: This is the prespecified …

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POLYMIXIN B IMMOBILIZED FIBER IMPROVES HYPERDYNAMIC STATE IN MRSA SEPTIC PATIENTS

Tomoyuki Kawamata, Hitoshi Imaizumi, Ryoichi Honda, Katsuji Torimoto et autres

Kawamata, Tomoyuki; Imaizumi, Hitoshi; Honda, Ryoichi; Torimoto, Katsuji; Yoshida, Masashi; Ura, Nobuyuki; Kaneko, Masamitsu Author Information

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5th Japanese Association of Hepato-Biliary-Pancreatic Surgery

Kohji Miyazaki, Nobuo Tsutsumi, Kenji Kitahara, M. Mori et autres

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Antitumor Activity of Activated Lymphocytes and Macrophages by Liposome-borne Tumor-specific Transplantation Antigens on Postsurgical Tumor Recurrence in Murine

Takashi Sato, Akira Okazaki, Katsuji Torimoto, Tadashi Katsuramaki et autres

Liposome-borne tumor-specific transplantation antigens (TSTA) potentiated the antitumor activity of cytotoxic lymphocytes and macrophages (Mφ) much more efficiently than empty liposomes in murine. Mφ obtained from peritoneum and lung as well as cytotoxic T-lymphocytes (CTL) such as lymphokine-activat-ed killer (LAIC) cells and …

Development of multiple necrotizing enteritis induced by a tumor necrosis factor-like cytokine from lipopolysaccharide-stimulated peritoneal macrophages in rats.

Katsuji Torimoto, Naoko Sato, Mamoru Okubo, A Yagihashi et autres

We report the development of an animal model of multiple necrotizing enteritis (MNE) in rats. When rats were injected directly with a culture supernatant of lipopolysaccharide (LPS)-stimulated rat peritoneal macrophages into the abdominal aorta, the overt pathologic lesions of MNE developed within …

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Establishment of rat multiple necrotizing enteritis(MNE) model. Involvement of TNF and analysis of mechanism of MNE development.

Katsuji Torimoto, Noriyuki Sato

Heat- or stress-inducible transformation-associated cell surface antigen on the activated H-ras oncogene-transfected rat fibroblast.

A Konno, Naoyuki Sato, A Yagihashi, Toshihiko Torigoe et autres

A WKA rat fetus fibroblast (WFB) was transfected by several oncogenes including EJras (activated H-ras), polyoma middle T (PyMT), v-src, c-myc, and adenovirus type 12 E1A-E1B. We analyzed the expression of the transformation-associated cell surface antigens on WFB by developing monoclonal antibodies. …

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Identification by monoclonal antibody of the tumor antigen of a human autologous breast cancer cell that is involved in cytotoxicity by a cytotoxic T-cell clone.

Mamoru Okubo, Naoko Sato, Y Wada, Shingo Takahashi et autres

We have already established a pair of human autologous clones, tumor-specific cytotoxic T-lymphocyte clone TcHMC-1 and tumor target clone HMC-1-8, that were derived from the metastatic pleural effusion of a patient with mammary carcinoma. In this paper, we describe the target antigen …

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