Ursula Müller

Metabolic long‐term monitoring of transcorneal electrical stimulation in retinitis pigmentosa

Olga Maria Zabek, Nesrin Meral, Hanna Camenzind Zuche, Ursula Müller et autres

Abstract Purpose: Transcorneal electrical stimulation (TES) is a new therapeutical approach for retinitis pigmentosa (RP). With progression of RP, degeneration of photoreceptors results in lower oxygen consumption of the retina. Retinal oximetry (RO) is a noninvasive method to analyse oxygen saturation in …

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Metabolic Long-Term Monitoring of Transcorneal Electrical Stimulation in Retinitis Pigmentosa

Nesrin Meral, Olga Maria Zabek, Hanna Camenzind Zuche, Ursula Müller et autres

INTRODUCTION: Transcorneal electrical stimulation (TES) is a new therapeutical approach for retinitis pigmentosa (RP). With progression of RP, degeneration of photoreceptors results in lower oxygen consumption of the retina. Retinal oximetry (RO) is a noninvasive method to analyze oxygen saturation in retinal …

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Optical coherence tomography angiography findings in patients undergoing transcorneal electrical stimulation for treating retinitis pigmentosa

Olga Maria Zabek, Hanna Camenzind Zuche, Ursula Müller, Hendrik P. N. Scholl et autres

Data underlying the figures in the publication “Optical coherence tomography angiography findings in patients undergoing transcorneal electrical stimulation for treating retinitis pigmentosa”, published in Graefes Arch Clin Exp Ophthalmol, 2021, 259, 1167–1177. https://doi.org/10.1007/s00417-020-04963-7 Table of contents: 1. Table 1; Word file containing …

Optical coherence tomography angiography findings in patients undergoing transcorneal electrical stimulation for treating retinitis pigmentosa

Olga Maria Zabek, Hanna Camenzind Zuche, Ursula Müller, Hendrik P. N. Scholl et autres

Data underlying the figures in the publication “Optical coherence tomography angiography findings in patients undergoing transcorneal electrical stimulation for treating retinitis pigmentosa”, published in Graefes Arch Clin Exp Ophthalmol, 2021, 259, 1167–1177. https://doi.org/10.1007/s00417-020-04963-7 Table of contents: 1. Table 1; Word file containing …

Optical coherence tomography angiography findings in transcorneal electrical stimulation in retinitis pigmentosa

Olga Maria Zabek, Hanna Camenzind Zuche, Ursula Müller, Hendrik P. N. Scholl et autres

Purpose Transcorneal electrical stimulation (TES) is a novel treatment approach for patients with retinitis pigmentosa (RP). The aim of our study was to observe changes in optical coherence tomography angiography (OCTA) that would be attributed to TES treatment. Methods A total of …

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Optical coherence tomography angiography findings in patients undergoing transcorneal electrical stimulation for treating retinitis pigmentosa

Olga Maria Zabek, Hanna Camenzind Zuche, Ursula Müller, Hendrik P. N. Scholl et autres

PURPOSE: Transcorneal electrical stimulation (TES) is a novel treatment approach for patients with retinitis pigmentosa (RP). The aim of our study was to observe changes in optical coherence tomography angiography (OCTA) that would be attributed to TES treatment. METHODS: A total of …

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Evidence for a role of RUNX1 as recombinase cofactor for TCRβ rearrangements and pathological deletions in ETV6-RUNX1 ALL

Volkhard Seitz, Karsten Kleo, Anja Dröge, Sigrid Schaper et autres

Abstract T-cell receptor gene beta (TCRβ) gene rearrangement represents a complex, tightly regulated molecular mechanism involving excision, deletion and recombination of DNA during T-cell development. RUNX1, a well-known transcription factor for T-cell differentiation, has recently been described to act in addition as …

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Retinal vessel oximetry as a sensitive metabolic monitoring method for transcorneal electrical stimulation in retinitis pigmentosa

Maria della Volpe Waizel, Hanna Camenzind Zuche, Ursula Müller, Hendrik P. N. Scholl et autres

Abstract Background Transcorneal electrical stimulation (TES; OkuStim ® ) is a novel therapy method for patients with retinitis pigmentosa (RP). With progression of RP, loss of photoreceptors leads to less oxygen consumption and lower demand in the inner retina. Retinal oximetry (RO) …

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Metabolic monitoring of transcorneal electrical stimulation in retinitis pigmentosa

Maria della Volpe Waizel, Hanna Camenzind Zuche, Ursula Müller, Annekatrin Rickmann et autres

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Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood

Stephanie Stanelle‐Bertram, Kerstin Walendy-Gnirß, Thomas Speiseder, Swantje Thiele et autres

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RUNX1 cooperates with FLT3-ITD to induce leukemia

Kira Behrens, Katrin Maul, Nilgün Solak Tekin, Neele Kriebitzsch et autres

Acute myeloid leukemia (AML) is induced by the cooperative action of deregulated genes that perturb self-renewal, proliferation, and differentiation. Internal tandem duplications (ITDs) in the FLT3 receptor tyrosine kinase are common mutations in AML, confer poor prognosis, and stimulate myeloproliferation. AML patient …

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Runx1 downregulates stem cell and megakaryocytic transcription programs that support niche interactions

Kira Behrens, Ioanna Triviai, Maike Schwieger, Nilgün Solak Tekin et autres

Disrupting mutations of the RUNX1 gene are found in 10% of patients with myelodysplasia (MDS) and 30% of patients with acute myeloid leukemia (AML). Previous studies have revealed an increase in hematopoietic stem cells (HSCs) and multipotent progenitor (MPP) cells in conditional …

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