Bart van Grinsven

Supercritical CO2–Driven Design of Beryllium Molecularly Imprinted Polymers for Thermal Biosensors

Ana I. Furtado, Sérgio F. Sousa, Bart van Grinsven, Joseph W. Lowdon et autres

Abstract Supercritical carbon dioxide (scCO2) offers a sustainable medium for molecularly imprinted polymer (MIP) synthesis, yet rational monomer selection under supercritical conditions remains largely unexplored. Here, molecular dynamics (MD) simulations were used as a pre–polymerization screening tool to investigate template–monomer interactions for …

pt, nl (code pays fourni par la source)

Molecular Rotors: From Newtonian Fluids to Functional Materials as Viscosity and Temperature Sensing Tools

Flavia Di Scala, Alice Briole, Valerii Myndrul, Thomas Jan Cleij et autres

ABSTRACT Molecular rotors (MRs) are a distinctive class of fluorescent molecules whose photophysical properties are influenced by their surrounding environment, making them valuable as viscosity nanosensors. However, interpreting their fluorescence responses in complex systems poses a significant challenge, as these environments can …

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Fungal Spore Detection of the Gray Mold Crop Disease: Imprinted-Polymer Thermometric Sensing Platform for the Real-Time Monitoring of Botrytis cinerea

Rocio Arreguin-Campos, Ramiro Marroquin-Garcia, Augusto César Parreiras de Jesus, Ulrike Zanzen et autres

High Resolution Image Download MS PowerPoint Slide Timely identification of pathogens within the food production chain is crucial to prevent spoilage and reduce the substantial economic burden associated with crop loss. Botrytis cinerea is the causative agent of gray mold disease, which …

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SYNTHESIS OF FLUORINE-18 LABELLED RADIOLIGANDS FOR PET IMAGING OF GABA TRANSPORTER 1 (GAT1)

Niels Knippenberg, Matthias Bauwens, Vincent Ornelis, Alexandru Florea et autres

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Detection of Anti- Mycobacterium leprae Antibodies in Leprosy Contacts Using a Label-Free Approach with the Heat-Transfer Method

Augusto César Parreiras de Jesus, Rocio Arreguin-Campos, Valerii Myndrul, Ana Laura Grossi de Oliveira et autres

Early detection of Mycobacterium leprae infection is essential to interrupt leprosy transmission and guide prophylactic interventions. Current diagnostic strategies rely largely on clinical signs, and laboratory tools lack sensitivity to detect asymptomatic individuals, who can play a critical role in disease transmission …

br, nl (code pays fourni par la source)

Colorimetric sensing of sinapic acid in mustard seeds based on DES-modified imprinted polymers and Cu(II) complexation

Gil van Wissen, Flavia Di Scala, Ramiro Marroquin-Garcia, Joseph William Lowdon et autres

Accurate in-field quantification of antioxidants in food is essential for straightforward assessment of nutritional value. To this purpose, a MIP-based colorimetric assay based on the strong chromogenic complexation between the natural antioxidant sinapic acid and Cu(II) for direct detection in food samples …

nl (code pays fourni par la source)

Biosensor-Based Platforms for the Detection and Screening of Mycobacterium leprae Infection

Augusto César Parreiras de Jesus, Ana Laura Grossi de Oliveira, Flavia Di Scala, Cristiane Alves da Silva Menezes et autres

Leprosy remains an important neglected tropical disease with about 200,000 new cases detected annually worldwide. Although the disease is highly responsive to treatment, a timely and accurate diagnosis continues to be a critical barrier to disease control. Traditional diagnostic methods, including PCR, …

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A Multiepitope Protein Based on Selected Synthetic Peptides Enables Effective Serological Screening of Exposure to Mycobacterium leprae

Augusto César Parreiras de Jesus, Tatyane Martins Cirilo, José Bryan da Rocha Rihs, Tânia Mara Pinto Dabés Guimarães et autres

High Resolution Image Download MS PowerPoint Slide Early and accurate identification of individuals exposed to leprosy is essential for controlling the transmission. Our study assessed the potential of a novel recombinant multiepitope protein, designed using five synthetic Mycobacterium leprae -specific peptides that …

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Drug-Checking with Molecularly Imprinted Polymers: Addressing Xylazine-Contaminated Fentanyl

Ramiro Marroquin‐Garcia, Gil van Wissen, Rocio Arreguin-Campos, Gabriela Goraşov et autres

Xylazine adulterated Fentanyl is considered one of the deadliest drug threats ever faced in the United States. However, due to the complexity of the illegal drug supply, xylazine detection in the frame of drug-checking (harm reduction) remains an unsolved challenge, one which …

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Novel low-cost instrumentation based on an RGB sensor using molecularly imprinted polymers (MIPs) for the rapid detection of aqueous 2-methoxphenidine (2-MXP)

Serguei Stoukatch, F. Dupont, Joseph William Lowdon, Gil van Wissen et autres

In this paper, we demonstrate a novel, cost-effective sensing system utilizing a molecularly imprinted polymer (MIP) for the indirect colorimetric detection of 2-methoxphenidine (2-MXP). Unlike other colorimetric methods that often require expensive spectrometers and bulky read-out equipment, our system is streamlined, employing …

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Porogenic Solvents in Molecularly Imprinted Polymer Synthesis: A Comprehensive Review of Current Practices and Emerging Trends

Gil van Wissen, Joseph William Lowdon, Thomas Jan Cleij, Kasper Eersels et autres

The versatility of molecularly imprinted polymers (MIPs) has led to their integration into applications like biosensing, separation, environmental monitoring, and drug delivery technologies. This diversity of applications has resulted in a plethora of synthesis approaches to precisely tailor the materials' properties to …

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Tracking Perfluorooctanoic Acid in Tap and River Water Employing Screen-Printed Electrodes Modified with Molecularly Imprinted Polymers

Fatemeh Ahmadi Tabar, Joseph William Lowdon, Margaux Frigoli, Robert D. Crapnell et autres

High Resolution Image Download MS PowerPoint Slide While existing polyfluoroalkyl substances (PFAS) detection techniques are highly sensitive, their broader implementation is limited by the need for expensive equipment, lengthy analysis times, and specialized personnel. This underscores the need for fast, reliable, cost-effective, …

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