Margaux Frigoli

Tracking Perfluorooctanoic Acid in Tap and River Water Employing Screen-Printed Electrodes Modified with Molecularly Imprinted Polymers

Fatemeh Ahmadi Tabar, Joseph William Lowdon, Margaux Frigoli, Robert D. Crapnell et autres

High Resolution Image Download MS PowerPoint Slide While existing polyfluoroalkyl substances (PFAS) detection techniques are highly sensitive, their broader implementation is limited by the need for expensive equipment, lengthy analysis times, and specialized personnel. This underscores the need for fast, reliable, cost-effective, …

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Thermal sensing of syringic acid in food samples via molecularly imprinted polymers synthesized from bio-based deep eutectic solvents as monomers

Gil van Wissen, Ramiro Marroquin‐Garcia, Margaux Frigoli, Joseph William Lowdon et autres

Sensing syringic acid in food samples is highly valuable in food quality control due to its health promoting effects. To this purpose, syringic acid MIPs aligning with green chemistry have been developed by employing a bio-based functional monomer as DES and ethanol-water …

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Molecular Rotors: A real-time approach to assess polymerization process

Flavia Di Scala, Valerii Myndrul, Margaux Frigoli, Hanne Diliën et autres

In this study, we used molecular rotors (MRs) to monitor the polymerization of polydimethylsiloxane (PDMS) in real-time, providing a correlation between its viscoelastic properties and farnesyl-(2- carboxy-2-cyanovinyl)-julolidine (FCVJ) fluorescent emission. Monitoring polymerization in real-time enables the optimization of material properties while minimizing …

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Detection of antibiotic sulfamethoxazole residues in milk using a molecularly imprinted polymer-based thermal biosensor

Margaux Frigoli, Joseph William Lowdon, Thomas Jan Cleij, Hanne Diliën et autres

Antibiotic resistance is a growing concern, partly due to inadequate inspections in the food safety chain. The accumulation of antibiotics like sulfamethoxazole (SMX) in animal products contributes to the rise of resistant microorganisms, posing a global health challenge. This work focuses on …

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Fighting bacterial infections and antibiotic resistance with molecularly imprinted polymer-based sensors

Margaux Frigoli

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Electrochemical Sensors for Antibiotic Detection: A Focused Review with a Brief Overview of Commercial Technologies

Margaux Frigoli, Mikolaj P. Krupa, Geert Hooyberghs, Joseph William Lowdon et autres

Antimicrobial resistance (AMR) poses a significant threat to global health, powered by pathogens that become increasingly proficient at withstanding antibiotic treatments. This review introduces the factors contributing to antimicrobial resistance (AMR), highlighting the presence of antibiotics in different environmental and biological matrices …

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Electrochemical Detection of Pseudomonas aeruginosa Quorum Sensing Molecule ( S )- N -Butyryl Homoserine Lactone Using Molecularly Imprinted Polymers

Margaux Frigoli, Joseph William Lowdon, Nicolas Donetti, Robert D. Crapnell et autres

High Resolution Image Download MS PowerPoint Slide Pseudomonas aeruginosa is a multidrug-resistant Gram-negative bacterium that poses a significant threat to public health, necessitating rapid and on-site detection methods for rapid recognition. The goal of the project is therefore to indirectly detect the …

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Development towards a novel screening method for nipecotic acid bioisosteres using molecular imprinted polymers (MIPs) as alternative to in vitro cellular uptake assays

Niels Knippenberg, Joseph William Lowdon, Margaux Frigoli, Thomas Jan Cleij et autres

Impaired expression of GABA transporters (GATs) is closely related to the pathogenesis of among others Parkinson's disease and epilepsy. As such, lipophilic nipecotic acid analogs have been extensively studied as GAT1-addressing drugs and radioligands but suffer from limited brain uptake due to …

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Emerging Biomimetic Sensor Technologies for the Detection of Pathogenic Bacteria: A Commercial Viability Study

Margaux Frigoli, Joseph William Lowdon, Manlio Caldara, Thomas Jan Cleij et autres

Ensuring a rapid and accurate identification of harmful bacteria is crucial in various fields including environmental monitoring, food safety, and clinical diagnostics. Conventional detection methods often suffer from limitations such as long analysis time, complexity, and the need for qualified personnel. Therefore, …

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Gold screen-printed electrodes coupled with molecularly imprinted conjugated polymers for ultrasensitive detection of streptomycin in milk

Margaux Frigoli, Manlio Caldara, Jeroen Royakkers, Joseph William Lowdon et autres

Antibiotic resistance is a global health threat, challenging traditional treatments and complicating the food safety process. This study introduces an electrochemical detection method for streptomycin sulfate, utilizing gold screen-printed electrodes (Au-SPE) functionalized via electropolymerization of a custom-made naphthalene diimide-based conjugated monomer (Th2-NDI-PIA). …

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Tracking Pfoa in Tap Water Employing Screen-Printed Electrodes Modified with Molecularly Imprinted Polymers

Fatemeh Ahmadi Tabar, Joseph William Lowdon, Margaux Frigoli, Robert D. Crapnell et autres

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Thermal Pyocyanin Sensor Based on Molecularly Imprinted Polymers for the Indirect Detection of Pseudomonas aeruginosa

Margaux Frigoli, Joseph William Lowdon, Manlio Caldara, Rocio Arreguin-Campos et autres

High Resolution Image Download MS PowerPoint Slide Pseudomonas aeruginosa is a ubiquitous multi-drug-resistant bacterium, capable of causing serious illnesses and infections. This research focuses on the development of a thermal sensor for the indirect detection of P. aeruginosa infection using molecularly imprinted …

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