Haruhiko Michimata

Risk factors for severe immune‐related pneumonitis after nivolumab plus ipilimumab therapy for non‐small cell lung cancer

Toshiyuki Sumi, Motoki Sekikawa, Yuta Koshino, Daiki Nagayama et autres

BACKGROUND: The efficacy of anti-CTLA-4 antibody (ipilimumab) plus anti-programmed cell death 1 antibody (nivolumab) in treating advanced non-small cell lung cancer (NSCLC) is impeded by an elevated risk of severe immune-related adverse events. However, our understanding of associations among pre-existing fibrosis, emphysematous …

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The Usefulness of Transesophageal Ultrasound-guided Bronchoscopic Aspiration for Neoplastic Lesions Inside and Outside the Lungs Adjacent to the Esophagus

Toshiyuki Sumi, Haruhiko Michimata, Daiki Nagayama, Yuta Koshino et autres

Background: Optimal management of lung cancer requires an accurate diagnosis and a safe and comfortable examination method allowing acceptable rebiopsy. Endoscopic ultrasound with bronchoscope-guided fine-needle aspiration (EUS-B-FNA) is associated with lesser pain than endoscopic ultrasound-guided fine-needle aspiration but has the same diagnostic …

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Diagnosis of Lymphangitis Carcinomatosa Using Cryobiopsy after Surgical Treatment for Lung Adenocarcinoma

Toshiyuki Sumi, Daiki Nagayama, Haruhiko Michimata, Yuta Koshino et autres

Lymphangitis carcinomatosa is a type of pulmonary metastasis with a poor prognosis. Transbronchial lung biopsy and bronchoalveolar lavage (BAL) are used for its histologic diagnosis, but improved diagnostic yield is needed. Transbronchial lung cryobiopsy (TBLC) is useful in diagnosing interstitial lung diseases …

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Transbronchial cryobiopsy for small peripheral pulmonary lesions using endobronchial ultrasonography and an ultrathin bronchoscope

Toshiyuki Sumi, Yuichi Yamada, Yuta Koshino, Hiroki Watanabe et autres

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Severe heart failure due to peripartum cardiomyopathy

Haruhiko Michimata, Toshiyuki Sumi, Daiki Nagayama, Yuta Koshino et autres

Perinatal cardiomyopathy presents similarly to dilated cardiomyopathy and should be suspected in perinatal women presenting with dyspnoea, even with no previous history of heart disease.

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Pneumocystis Pneumonia Infection Following the Initiation of Pembrolizumab Therapy for Lung Adenocarcinoma

Toshiyuki Sumi, Kazuya Takeda, Haruhiko Michimata, Daiki Nagayama et autres

Pneumocystis pneumonia (PCP) is an opportunistic infection that presents a ground-glass appearance in the lungs on chest radiography. Interstitial lung disease is a commonly reported adverse effect of immune checkpoint inhibitor (ICI) treatment; however, there are few reports of ICI treatment-associated PCP …

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Risk factors for severe immune-related adverse events after first-line pembrolizumab monotherapy or combination chemotherapy for non-small-cell lung cancer

Toshiyuki Sumi, Yuta Koshshino, Motoki Sekikawa, Yuta Nagahisa et autres

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Tumor-Associated Raynaud’s Phenomenon Exacerbated by Administration of Immune Checkpoint Inhibitors

Toshiyuki Sumi, Haruhiko Michimata, Daiki Nagayama, Yuta Koshino et autres

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Hemothorax as a complication of transbronchial lung cryobiopsy

Haruhiko Michimata, Toshiyuki Sumi, Yoshiko Keira, Daiki Nagayama et autres

There are more complications in transbronchial lung cryobiopsy than in a conventional transbronchial lung biopsy. Respiratory endoscopists should be aware of the potential complications, including rare complications such as hemothorax.

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Cytokine release syndrome in a patient with non-small cell lung cancer on ipilimumab and nivolumab maintenance therapy after vaccination with the mRNA-1273 vaccine: a case report

Toshiyuki Sumi, Yuta Koshino, Haruhiko Michimata, Daiki Nagayama et autres

Background: Cytokine release syndrome (CRS) is caused by the release of inflammatory cytokines that appear during or immediately after administration of a therapeutic antibody and can cause a variety of symptoms. COVID-19 vaccination is effective in cancer patients and prevents breakthrough infections. …

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Diffuse large B ‐cell lymphoma with cardiac invasion diagnosed using transesophageal ultrasound‐guided bronchoscopic aspiration

Daiki Nagayama, Toshiyuki Sumi, Yoshiko Keira, Yusuke Tanaka et autres

Transesophageal ultrasound-guided bronchoscopic aspiration (EUS-B-FNA) allowed for minimally invasive and simultaneous diagnosis and evaluation of the degree of invasion by echocardiography. EUS-B-FNA may be useful for the evaluation and diagnosis of tumours with cardiac invasion.

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