Melanie Knowles

Abstract No. 171 Treatment Outcomes and Healthcare Resource Utilization in Computer--Assisted Vacuum Thrombectomy versus Open Embolectomy: The THRIVE Study

Carrie Bailey, Banu Arslan, Sameh Sayfo, Fakhir Elmasri et autres

Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery

Mark Edwards, Gordon Forbes, Neil Walker, Dion Morton et autres

INTRODUCTION: Postoperative morbidity and mortality in patients undergoing major emergency gastrointestinal surgery are a major burden on healthcare systems. Optimal management of perioperative intravenous fluids may reduce mortality rates and improve outcomes from surgery. Previous small trials of cardiac-output guided haemodynamic therapy …

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Protection against discrimination in national dementia guideline recommendations: A systematic review

Tiffeny James, Naaheed Mukadam, Andrew Sommerlad, Hossein Rostami Pour et autres

BACKGROUND: National dementia guidelines provide recommendations about the most effective approaches to diagnosis and interventions. Guidelines can improve care, but some groups such as people with minority characteristics may be disadvantaged if recommended approaches are the same for everyone. It is not …

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Heart rate variability in relation to cognition and behavior in neurodegenerative diseases: A systematic review and meta-analysis

Kathy Liu, Thomas Elliott, Melanie Knowles, Robert Howard

Neurodegenerative diseases, which frequently present with neuropsychiatric symptoms related to prefrontal cortical dysfunction, can alter the integrity of the neural networks involved in central autonomic nervous system regulation, which is proposed to be indexed by heart rate variability (HRV). We systematically reviewed …

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Acute mental health presentations before and during the COVID-19 pandemic

Naaheed Mukadam, Andrew Sommerlad, Jessica Wright, Abigail Smith et autres

BACKGROUND: A number of community based surveys have identified an increase in psychological symptoms and distress but there has been no examination of symptoms at the more severe end of the mental health spectrum. AIMS: We aimed to analyse numbers and types …

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Cyberpsychiatry versus COVID-19: using video consultation to improve clinical care in an in-patient psychiatric unit

Sarah Moslehi, Dominic Aubrey-Jones, Melanie Knowles, Janet Obeney-Williams et autres

The COVID-19 pandemic has resulted in unique challenges for in-patients across the National Health Service as visitors, both family and friends, are prevented from visiting patients owing to infection prevention and control measures. The Attend Anywhere platform was used as the basis …

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Pharmacological treatment trials of agitation in Alzheimer's disease: A systematic review of ClinicalTrials.gov registered trials

Kathy Liu, Anna Borissova, Jansher Mahmood, Thomas M. Elliott et autres

INTRODUCTION: There is increasing emphasis on the importance of optimizing and standardizing clinical trials of agitation in Alzheimer's disease (AD), but the risks of bias arising from published trials and the number and design of unpublished studies are poorly understood. METHODS: Using …

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Psychiatry and Covid-19: Acute mental health presentations before and during the pandemic

Naaheed Mukadam, Andrew Sommerlad, Jessica Wright, Abigail Smith et autres

BackgroundWe aimed to analyse numbers and types of psychiatric presentations to inform planning for future demand on mental health services in light of the Covid-19 pandemic. MethodsWe analysed electronic data between January and April 2020 for 2,534 patients referred to acute psychiatric …

Containing COVID: the establishment and management of a COVID-19 ward in an adult psychiatric hospital

Melanie Knowles, Golnar Aref-Adib, Sarah Moslehi, Dominic Aubrey-Jones et autres

BACKGROUND: As the coronavirus disease 2019 (COVID-19) epidemic in the UK emerged and escalated, clinicians working in mental health in-patient facilities faced unique medical, psychiatric and staffing challenges in managing and containing the impact of the virus and, in the context of …

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Developing a Bike-Sharing Program at Kent State University and Kent, Ohio

David H. Kaplan, Gina M. Butrico, Rachel Will, Andrea Szell et autres

Sustainable transportation frequently describes the use of non-motorized transportation sources, primarily walking and bicycling (Toor and Havlick, 2004). Walking is a time honored method of getting around that most people can easily access. But bicycling is a mode of transportation that requires …

Peer-reviewed paper Surveillance of meticillin-resistant Staphylococcus aureus in community hospitals in North Cumbria in 2005

Paul Weaving, P. Blaylock, A. Galdins, Melanie Knowles et autres

his paper describes a three-month surveillance project performed to determine the incidence of meticillin-resistant Staphylococcus aureus carriage on admission to community hospitals in North Cumbria. The survey also attempted to identify the rate of acquisition of MRSA in the community hospitals during …

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A school and community outbreak of influenza A.

Cynthia H. Brock, Melanie Knowles

In May 1995 a department of public health medicine was informed of an outbreak of respiratory and gastrointestinal illness in a local school. Eighty-three pupils and staff were affected out of a total of 247 people--an attack rate of 34%. The outbreak …

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