Xia He

Upfront Autologous Stem Cell Transplantation in First Complete Remission for Advanced‐Stage Extra‐Nodal NK /T‐Cell Lymphoma: A Multicenter Retrospective Study

Shaoxuan Hu, Liu W, Zhao Lj, W R Huang et autres

The aim of this study was to evaluate the effect of upfront autologous stem cell transplantation (ASCT) on the prognosis in patients with advanced-stage extra-nodal NK/T-cell lymphoma (NKTCL) achieving first complete remission (CR1) after frontline therapy. To this end, we retrospectively reviewed …

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Breaking through tradition: A new study on the 125 I seeds implantation assisted by the puncture angle guidance device

Yufeng Zhang, Yong Feng, Wenjie Guo, Xia He et autres

Abstract This study was conducted to compare the difference between the use of a puncture angle guide device assisted needle insertion and manual needle entry for the treatment of single metastatic lymph nodes above the thoracic entrance by 125 I seeds implantation, …

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The correlation between YTHDF1 gene polymorphism and cognitive dysfunction after radiotherapy for glioma

Huanfeng Zhu, Xiyun Shi, Dan Zong, Xia He

Background Gliomas are the most common primary malignant tumors of the central nervous system. Mounting evidence highlights the crucial role of YTH N6-methyladenosine RNA binding protein 1 (YTHDF1) in glioma treatment response. This study aimed to investigate the association between single nucleotide …

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APG-1252 enhances the anticancer role of paclitaxel in non-small-cell lung cancer cells by suppressing the extracellular regulated protein kinases/myeloid cell leukemia 1 pathway

Luxi Qian, Zizhang Guo, Xiang Cao, Huanfeng Zhu et autres

The efficacy of paclitaxel (PTX), an important chemotherapy drug in non-small-cell lung cancer (NSCLC) cells, is limited by its resistance. APG-1252 has an inhibitory role in cancer and can inhibit myeloid cell leukemia 1 (MCL-1) to enhance chemotherapy drugs' antitumor effect. Therefore, …

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Risk-Adapted Combined-Modality Therapy in Early-Stage Extranodal Natural Killer-/T-Cell Lymphoma: A Markov Model–Based Cost-Effectiveness Analysis

Jing Yang, Qiu-Zi Zhong, Li-Ting Qian, Yong Yang et autres

PURPOSE: Combined-modality therapy (CMT) improves survival in patients with early-stage extranodal natural killer-/T-cell lymphoma (ENKTCL) compared with radiotherapy (RT) alone. However, the effect is inadequate for low-risk patients as defined by nomogram-revised risk index (NRI). As such, it remains unclear whether the …

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An ambispective, observational real-world study of tumor-treating fields for treatment of Chinese patients with newly diagnosed or recurrent/progressive glioblastoma

Guanzhang Li, Xiaoguang Qiu, Wei Zhang, Man Hu et autres

Background: Glioblastoma is the most common and aggressive central nervous system malignancy with poor prognosis. Tumor-treating fields (TTFields), approved in China in May 2020, represents a significant advancement in GBM treatment. Leveraging the extensive real-world data accumulated in the Chinese Medical Information …

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Validation of the Longitudinal Effect of an Integrated Nursing Intervention Based on the Integrated Theory of Health Behavior Change (ITHBC) on Multidimensional Health Indicators in Older Radiotherapy Patients

Jing Jiang, Jie Chen, Juan Lü, Huanfeng Zhu et autres

Introduction: The Integrated Theory of Health Behavior Change (ITHBC) offers a structured framework for promoting sustained health behavior change through cognitive beliefs, self-regulation, and social facilitation. However, its application in geriatric oncology remains unexplored. Methods: This quasi-experimental study enrolled 291 older adult …

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Clinical effect of voice therapy in the treatment of teachers' voice disorders patients combined subjective and objective assessment

Wenjun Guo, Libing Sun, Xia He, Wenyong Yu et autres

Objective To explore the curative effectiveness of comprehensive voice training methods on teachers' voice disorders patients by using subjective and objective assessment. Methods Forty-seven teachers' voice disorders patients suffering from voice symptoms without organic disease and complete follow-up data as the research …

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The effective evaluation of nurse-patient communication in relieving psychological anxiety of patients with tumor

Xia He

Objective The purpose of this study is to evaluate the effectiveness in relieving psychological anxiety by establishing system of psycho-communication between nurses and patients and healthy education for patients with tumor.Methods 50 patients with anxiety were screened by the Geriatric Depression Scale(GDS).In …